• 1. An approach to asymmetric synthesis of β-aryl alanines by Pd(0)-catalyzed cross-coupling and cyanate-to-isocyanate rearrangement?
  Piotr Szcze?niak,Sebastian Stecko RSC Adv., 2015,5, 30882-30888
• 2. An artificial CO-releasing metalloprotein built by histidine-selective metallation?
  Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Trifluoromethylbenzenes

Comprehensive Guide to 1-2-Chloro-4-(trifluoromethyl)phenylhydrazine (CAS No. 86398-98-3): Properties, Applications, and Market Insights

1-2-Chloro-4-(trifluoromethyl)phenylhydrazine (CAS No. 86398-98-3) is a specialized organic compound widely recognized for its unique chemical structure and versatile applications in industrial and research settings. This compound, featuring a chloro and trifluoromethyl substituent on the phenyl ring, is particularly valued in the synthesis of advanced materials and fine chemicals. Its molecular formula, C₇H₆ClF₃N₂, highlights its role as a key intermediate in organic synthesis.

The growing interest in 1-2-Chloro-4-(trifluoromethyl)phenylhydrazine is driven by its applications in pharmaceutical research and agrochemical development. Researchers frequently search for "CAS 86398-98-3 uses" or "synthesis of 1-2-Chloro-4-(trifluoromethyl)phenylhydrazine," reflecting its relevance in drug discovery and crop protection. The compound's ability to act as a building block for heterocyclic compounds makes it indispensable in modern chemistry.

From a chemical properties perspective, 1-2-Chloro-4-(trifluoromethyl)phenylhydrazine exhibits notable stability under standard conditions, with a melting point ranging between 80-85°C. Its solubility in organic solvents like ethanol and dichloromethane facilitates its use in laboratory-scale reactions. The presence of both electron-withdrawing (trifluoromethyl) and electron-donating (hydrazine) groups contributes to its reactivity, enabling diverse functionalization pathways.

In the pharmaceutical industry, this compound is often explored for its potential in designing bioactive molecules. Recent studies highlight its utility in developing antimicrobial agents and enzyme inhibitors, addressing global health challenges such as antibiotic resistance. Searches like "86398-98-3 in drug development" underscore its significance in medicinal chemistry.

The agrochemical sector also leverages 1-2-Chloro-4-(trifluoromethyl)phenylhydrazine for synthesizing pesticide intermediates. With increasing demand for sustainable farming solutions, queries such as "trifluoromethyl phenylhydrazine derivatives in agriculture" are rising. This compound's role in creating herbicides and fungicides aligns with the industry's shift toward eco-friendly pest control.

Market trends indicate a steady growth in the demand for CAS 86398-98-3, particularly in Asia-Pacific and North America. Suppliers and manufacturers are focusing on scalable synthesis methods to meet industrial needs. Keywords like "buy 1-2-Chloro-4-(trifluoromethyl)phenylhydrazine" and "high-purity 86398-98-3" are frequently used by procurement specialists.

From a safety and handling perspective, standard laboratory precautions are recommended when working with 1-2-Chloro-4-(trifluoromethyl)phenylhydrazine. Proper ventilation, personal protective equipment (PPE), and adherence to local regulations ensure safe usage. Researchers often inquire about "storage conditions for 86398-98-3" to maintain compound integrity.

In summary, 1-2-Chloro-4-(trifluoromethyl)phenylhydrazine (CAS No. 86398-98-3) is a multifaceted compound with expanding applications in pharmaceuticals, agrochemicals, and material science. Its unique properties and adaptability to synthetic workflows make it a valuable asset for researchers and industries alike. As innovation continues, this compound is poised to play a pivotal role in addressing contemporary scientific and industrial challenges.

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