Cas no 85949-81-1 (8-Quinolinecarboxylic acid, hydrazide)

8-Quinolinecarboxylic acid hydrazide is a versatile heterocyclic compound featuring a quinoline core with a carboxylic acid hydrazide functional group. This structure imparts strong chelating properties, making it valuable in coordination chemistry and metal ion detection applications. The hydrazide moiety enhances reactivity, enabling its use as a precursor in synthesizing various derivatives, including heterocyclic scaffolds and Schiff bases. Its quinoline backbone contributes to potential biological activity, with applications in medicinal chemistry and agrochemical research. The compound exhibits stability under standard conditions, facilitating handling and storage. Its dual functionality allows for selective modifications, supporting its utility in organic synthesis and material science.
8-Quinolinecarboxylic acid, hydrazide structure
85949-81-1 structure
Product Name:8-Quinolinecarboxylic acid, hydrazide
CAS No:85949-81-1
MF:C10H9N3O
MW:187.197961568832
CID:662879
PubChem ID:10012684
Update Time:2025-05-24

8-Quinolinecarboxylic acid, hydrazide Chemical and Physical Properties

Names and Identifiers

    • 8-Quinolinecarboxylic acid, hydrazide
    • quinoline-8-carbohydrazide
    • Quinoline-8-carboxylic acid
    • AKOS005256711
    • 8-Quinolinecarboxylic acid hydrazide
    • 85949-81-1
    • CS-0252465
    • EN300-60433
    • SCHEMBL110552
    • DTXSID70434111
    • quinoline-8-carboxylic acid hydrazide
    • quinoline-8-carboxylic acid hydrazide, AldrichCPR
    • ANNUAPCFXNMTND-UHFFFAOYSA-N
    • Inchi: 1S/C10H9N3O/c11-13-10(14)8-5-1-3-7-4-2-6-12-9(7)8/h1-6H,11H2,(H,13,14)
    • InChI Key: ANNUAPCFXNMTND-UHFFFAOYSA-N
    • SMILES: O=C(C1=CC=CC2=CC=CN=C21)NN

Computed Properties

  • Exact Mass: 187.074561919g/mol
  • Monoisotopic Mass: 187.074561919g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 1
  • Complexity: 219
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.7
  • Topological Polar Surface Area: 68?2

Experimental Properties

  • Density: 1.297
  • Melting Point: 88-90 °CEnamineEN300-60433

8-Quinolinecarboxylic acid, hydrazide Security Information

8-Quinolinecarboxylic acid, hydrazide Pricemore >>

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Additional information on 8-Quinolinecarboxylic acid, hydrazide

Comprehensive Overview of 8-Quinolinecarboxylic acid, hydrazide (CAS No. 85949-81-1): Properties, Applications, and Research Insights

8-Quinolinecarboxylic acid, hydrazide (CAS No. 85949-81-1) is a specialized organic compound belonging to the quinoline family, renowned for its unique chemical structure and versatile applications in pharmaceuticals, agrochemicals, and material science. The compound features a quinoline backbone coupled with a carboxylic acid hydrazide functional group, making it a valuable intermediate in synthetic chemistry. Researchers and industries are increasingly interested in this molecule due to its potential in drug discovery, catalysis, and functional material design.

One of the most searched questions about 8-Quinolinecarboxylic acid, hydrazide revolves around its synthesis methods and purity optimization. The compound is typically synthesized via the condensation of 8-quinolinecarboxylic acid with hydrazine derivatives under controlled conditions. Advanced techniques like HPLC and NMR are employed to ensure high purity, which is critical for its application in sensitive fields such as medicinal chemistry. Recent studies highlight its role as a chelating agent, enabling the development of metal-organic frameworks (MOFs) with applications in gas storage and catalysis.

In the context of green chemistry, 8-Quinolinecarboxylic acid, hydrazide has garnered attention for its potential in sustainable synthesis. Researchers are exploring its use in biodegradable catalysts and eco-friendly corrosion inhibitors, aligning with global trends toward reducing environmental impact. The compound’s ability to form stable complexes with transition metals also makes it a candidate for renewable energy applications, such as photovoltaic materials and battery technologies.

The pharmaceutical industry has shown significant interest in 8-Quinolinecarboxylic acid, hydrazide due to its bioactive properties. Preliminary studies suggest its derivatives exhibit antimicrobial and antioxidant activities, sparking investigations into novel therapeutic agents. For instance, its structural similarity to known quinoline-based drugs like chloroquine has prompted research into its potential for treating infectious diseases. However, rigorous clinical validation is still underway.

From an SEO perspective, users frequently search for "CAS 85949-81-1 suppliers" or "8-Quinolinecarboxylic acid hydrazide price," reflecting commercial demand. The compound is available through specialized chemical suppliers, with pricing influenced by purity (>98% being the industry standard) and scale. Regulatory compliance, such as REACH and FDA guidelines, is another critical factor for buyers, ensuring safe handling and application.

In material science, 8-Quinolinecarboxylic acid, hydrazide is explored for its luminescent properties, particularly in designing OLEDs and sensors. Its ability to coordinate with lanthanides enhances emission efficiency, making it a promising candidate for next-generation display technologies. Additionally, its thermal stability and solubility profile are being optimized for 3D printing and nanotechnology applications.

Future research directions for 8-Quinolinecarboxylic acid, hydrazide include computational modeling to predict its reactivity and structure-activity relationships (SAR). Machine learning tools are being leveraged to accelerate the discovery of derivatives with enhanced properties. As interdisciplinary collaborations grow, this compound is poised to play a pivotal role in advancing precision medicine and smart materials.

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