• 1. Estimating and correcting interference fringes in infrared spectra in infrared hyperspectral imaging
  Ghazal Azarfar,Ebrahim Aboualizadeh,Nicholas M. Walter,Simona Ratti,Camilla Olivieri,Alessandra Norici,Michael Nasse,Achim Kohler,Mario Giordano Analyst, 2018,143, 4674-4683
• 2. Dissociative dynamics of O2 on Ag(110)?
  Ivor Lon?ari? Phys. Chem. Chem. Phys., 2015,17, 9436-9445
• 3. Emulsion soft templating of carbide-derived carbon nanospheres with controllable porosity for capacitive electrochemical energy storage?
  M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
• 4. Distinct correlation between (CN2)x units and pores: a low-cost method for predesigned wide range control of micropore size of porous carbon?
  Xiaotong Feng,Lei Bian,Jie Ma,Lei Zhou,Xiayan Wang,Guangsheng Guo,Qiaosheng Pu Chem. Commun., 2019,55, 3963-3966
• 5. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzenesulfonyl compounds Benzenesulfonyl halides

Comprehensive Overview of Benzenesulfonyl chloride, 3,6-dichloro-2-methyl- (CAS No. 856678-55-2)

Benzenesulfonyl chloride, 3,6-dichloro-2-methyl- (CAS No. 856678-55-2) is a specialized organic compound widely utilized in pharmaceutical and agrochemical research. This sulfonyl chloride derivative is recognized for its role as a key intermediate in synthesizing active ingredients for crop protection and drug development. Its molecular structure, featuring dichloro and methyl substituents, enhances reactivity in nucleophilic substitution reactions, making it valuable for constructing complex molecules.

In recent years, the demand for high-purity intermediates like 3,6-dichloro-2-methylbenzenesulfonyl chloride has surged due to advancements in green chemistry and sustainable synthesis. Researchers prioritize compounds with minimal environmental impact, aligning with global trends such as the UN Sustainable Development Goals (SDGs). This compound’s efficiency in catalytic reactions and compatibility with flow chemistry systems further elevates its relevance in modern labs.

A frequently searched question among chemists is: "How to optimize the synthesis of 3,6-dichloro-2-methylbenzenesulfonyl chloride?" Studies suggest that controlled chlorination of toluene derivatives followed by sulfonation yields higher purity. Another trending topic is its application in peptide coupling, where it acts as a sulfonating agent to activate carboxyl groups. These insights address common queries while emphasizing the compound’s versatility.

The analytical characterization of CAS No. 856678-55-2 involves techniques like HPLC, NMR, and mass spectrometry to ensure batch consistency—a critical factor for regulatory compliance in pharmaceuticals. Discussions on platforms like ResearchGate often highlight its stability under inert atmospheres, a detail crucial for storage protocols.

From an industrial perspective, supply chain resilience for such intermediates has become a hotspot, especially post-pandemic. Manufacturers now focus on localized production and digital inventory tracking to mitigate disruptions. This aligns with broader searches like "reliable suppliers of 3,6-dichloro-2-methylbenzenesulfonyl chloride", reflecting market needs.

In conclusion, Benzenesulfonyl chloride, 3,6-dichloro-2-methyl- exemplifies innovation at the intersection of chemistry and sustainability. Its multifaceted applications and alignment with industry 4.0 trends ensure its prominence in scientific and industrial discourse.

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