Cas no 856676-23-8 (Choline fenofibrate)

Choline fenofibrate is a choline salt derivative of fenofibric acid, primarily used as a lipid-modifying agent. It functions as a peroxisome proliferator-activated receptor alpha (PPAR-α) agonist, effectively reducing elevated triglyceride levels and increasing high-density lipoprotein (HDL) cholesterol. Compared to traditional fenofibrate, choline fenofibrate exhibits improved solubility and bioavailability, enhancing its pharmacokinetic profile. This formulation ensures more consistent absorption and reduced interpatient variability. Its mechanism of action involves activating lipoprotein lipase and inhibiting hepatic very-low-density lipoprotein (VLDL) synthesis. Choline fenofibrate is particularly suitable for patients with hypertriglyceridemia or mixed dyslipidemia, offering a well-tolerated therapeutic option with a favorable safety profile.

Choline fenofibrate structure

Product Name:Choline fenofibrate

CAS No:856676-23-8

MF:C₂₂H₂₈ClNO₅

MW:421.914425849915

MDL:MFCD18382233

CID:822665

PubChem ID:11350701

Update Time:2025-05-27

Choline fenofibrate Chemical and Physical Properties

Names and Identifiers

- 2-Hydroxy-N,N,N-trimethylethanaminium 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate
- Choline Fenofibrate
- ABT 335
- ABT-335
- Fenofibrate de choline
- fenofibric acid choline salt
- UNII-4BMH7IZT98
- Trilipix
- 4BMH7IZT98
- Choline fenofibrate [USAN:INN]
- HIP0901
- choline-fenofibrate
- Trilipix (TN)
- Choline fenofibrate (USAN/INN)
- JWAZHODZSADEHB-UHFFFAOYSA-M
- BCP28592
- 3320AC
- API0009427
- 2-Hydroxy-N,N,N-trimethyle
- CHEMBL1201745
- AS-10210
- C10AB11
- CHOLINE FENOFIBRATE [WHO-DD]
- Choline Fenofibrate;ABT-335
- FT-0665026
- D70702
- Choline fenofibrate (ABT-335)
- CHOLINE FENOFIBRATE (USP-RS)
- 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid choline salt
- 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate;2-hydroxyethyl(trimethyl)azanium
- cholini fenofibratum
- CHOLINE FENOFIBRATE [ORANGE BOOK]
- D08890
- 856676-23-8
- CHOLINE FENOFIBRATE [USP-RS]
- CS-0893
- Choline fenofibrate [USAN]
- DTXCID30157430
- Q27259379
- FENOFIBRIC ACID CHOLINE SALT [MI]
- A863484
- 2-Hydroxy-N,N,N-trimethylethanaminium 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
- CHOLINE FENOFIBRATE (MART.)
- 2-hydroxy-N,N,N-trimethylethan-1-aminium 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate
- Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-(4-(4- chlorobenzoyl)phenoxy)-2-methylpropanoic acid (1:1)
- 2-Hydroxy-N,N,N-trimethylethanaminium2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate
- ETHANAMINIUM, 2-HYDROXY-N,N,N-TRIMETHYL-, SALT WITH 2-(4-(4-CHLOROBENZOYL)PHENOXY)-2-METHYLPROPANOIC ACID (1:1)
- AKOS016010592
- 2-Hydroxy-N,N,N-trimethylethanaminium 2-(-(4-chlorobenzoyl)phenoxy)-2- methylpropanoate
- Fibricor
- CHOLINE FENOFIBRATE [MART.]
- HY-14739
- fenofibrato de colina
- 2-HYDROXY-N,N,N-TRIMETHYLETHANAMINIUM 2-(4-(4-CHLOROBENZOYL)PHENOXY)-2- METHYLPROPANOATE
- DTXSID50234939
- Fenofibric AcidDelayed-Release
- CHOLINE FENOFIBRATE [INN]
- MFCD18382233
- Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate (1:1); Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid (1:1) (9CI); ABT 335; Choline fenofibrate; FNFC; Trilipix
- DA-62297
- 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate,2-hydroxyethyl(trimethyl)azanium
- Choline fenofibrate
- MDL： MFCD18382233
- Inchi： 1S/C17H15ClO4.C5H14NO/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11;1-6(2,3)4-5-7/h3-10H,1-2H3,(H,20,21);7H,4-5H2,1-3H3/q;+1/p-1
- InChI Key： JWAZHODZSADEHB-UHFFFAOYSA-M
- SMILES： ClC1C=CC(=CC=1)C(C1C=CC(=CC=1)OC(C(=O)[O-])(C)C)=O.OCC[N+](C)(C)C

Computed Properties

Exact Mass: 421.16600
Monoisotopic Mass: 421.1656007g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 5
Heavy Atom Count: 29
Rotatable Bond Count: 6
Complexity: 446
Covalently-Bonded Unit Count: 2
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 86.7

Experimental Properties

Melting Point: 210-212°C
Boiling Point: 486.5°C at 760 mmHg
Flash Point: 248°C
Solubility: 生物體外In Vitro:DMSO溶解度6.2 mg/mL(14.70 mM;Need ultrasonic and warming)
PSA: 86.66000
LogP: 2.16320

Choline fenofibrate Security Information

Signal Word：warning
Hazard Statement： H303+H313+H333
Warning Statement： P264+P280+P305+P351+P338+P337+P313
Safety Instruction： H303+H313+H333
Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month

Choline fenofibrate Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-FX509-1g	Choline fenofibrate	856676-23-8	97+%	1g	418CNY	2021-05-08
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-FX509-5g	Choline fenofibrate	856676-23-8	97+%	5g	1324CNY	2021-05-08
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-FX509-200mg	Choline fenofibrate	856676-23-8	97+%	200mg	139CNY	2021-05-08
WU HAN AN JIE KAI Biomedical Technology Co., Ltd.	ajci6582-10mg	Choline Fenofibrate	856676-23-8	98%	10mg	￥516.00	2023-09-10
WU HAN AN JIE KAI Biomedical Technology Co., Ltd.	ajci6582-50mg	Choline Fenofibrate	856676-23-8	98%	50mg	￥629.00	2023-09-10
SHANG HAI TAO SHU Biotechnology Co., Ltd.	T3941-10 mg	Choline Fenofibrate	856676-23-8	99.95%	10mg	￥955.00	2022-04-26
SHANG HAI TAO SHU Biotechnology Co., Ltd.	T3941-25 mg	Choline Fenofibrate	856676-23-8	99.95%	25mg	￥2100.00	2022-04-26
SHANG HAI TAO SHU Biotechnology Co., Ltd.	T3941-100 mg	Choline Fenofibrate	856676-23-8	99.95%	100MG	￥7400.00	2022-04-26
SHANG HAI TAO SHU Biotechnology Co., Ltd.	T3941-1 mL * 10 mM (in DMSO)	Choline Fenofibrate	856676-23-8	99.95%	1 mL * 10 mM (in DMSO)	￥1050.00	2022-04-26
TRC	C432665-1mg	Choline Fenofibrate	856676-23-8		1mg	$74.00	2023-05-18

Choline fenofibrate Production Method

Choline fenofibrate Suppliers

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:856676-23-8)Choline fenofibrate

Order Number:A863484

Stock Status:in Stock

Quantity:10g

Purity:99%

Pricing Information Last Updated:Friday, 30 August 2024 08:41

Price ($):161.0

Email:[email protected]

Product Official Link

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