Cas no 85614-92-2 (5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide)

5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide is a heterocyclic organic compound featuring a pyridone core structure with a carboxamide substituent at the 3-position and a methyl group at the 5-position. This compound is of interest in pharmaceutical and agrochemical research due to its potential as a versatile intermediate in the synthesis of bioactive molecules. Its structural framework allows for further functionalization, making it valuable in medicinal chemistry for developing enzyme inhibitors or receptor modulators. The presence of both amide and pyridone moieties enhances its binding affinity and solubility, facilitating applications in drug discovery. High purity and stability under standard conditions ensure reliable performance in synthetic workflows.
5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide structure
85614-92-2 structure
Product Name:5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS No:85614-92-2
MF:C7H8N2O2
MW:152.150621414185
CID:1020658
PubChem ID:13004797
Update Time:2025-08-04

5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide Chemical and Physical Properties

Names and Identifiers

    • 5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide
    • 3-Pyridinecarboxamide,1,2-dihydro-5-methyl-2-oxo-(9CI)
    • 5-methyl-2-oxo-1H-pyridine-3-carboxamide
    • 2-Hydroxy-5-methylnicotinamide
    • SB53365
    • DTXSID20514836
    • 85614-92-2
    • 1822892-18-1
    • A863516
    • SCHEMBL16918372
    • MDL： MFCD18836709
    • Inchi： 1S/C7H8N2O2/c1-4-2-5(6(8)10)7(11)9-3-4/h2-3H,1H3,(H2,8,10)(H,9,11)
    • InChI Key： MNWFUPKKGZILFD-UHFFFAOYSA-N
    • SMILES： O=C1C(C(N)=O)=CC(C)=CN1

Computed Properties

  • Exact Mass: 152.05900
  • Monoisotopic Mass: 152.058577502g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 276
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.2
  • Topological Polar Surface Area: 72.2?2

Experimental Properties

  • PSA: 76.21000
  • LogP: 0.89480

5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide Customs Data

  • HS CODE：2933399090
  • Customs Data：

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide Pricemore >>

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5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide Suppliers

Amadis Chemical Company Limited
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(CAS:85614-92-2)5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide
Order Number:A863516
Stock Status:in Stock
Quantity:1g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 08:41
Price ($):472.0

5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide Related Literature

Additional information on 5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide

Recent Advances in the Study of 5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS: 85614-92-2)

The compound 5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS: 85614-92-2) has garnered significant attention in the field of chemical biology and medicinal chemistry due to its potential therapeutic applications. Recent studies have focused on elucidating its pharmacological properties, synthetic pathways, and mechanisms of action, making it a promising candidate for drug development. This research brief aims to summarize the latest findings related to this compound, providing insights into its current status and future prospects.

One of the key areas of investigation has been the synthesis and optimization of 5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide. Researchers have developed novel synthetic routes to improve yield and purity, which are critical for scaling up production. For instance, a 2023 study published in the Journal of Medicinal Chemistry reported a highly efficient three-step synthesis method, achieving a yield of over 85%. This advancement addresses previous challenges related to scalability and cost-effectiveness, paving the way for further preclinical and clinical studies.

In terms of pharmacological activity, recent in vitro and in vivo studies have demonstrated that 5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide exhibits potent anti-inflammatory and antioxidant properties. A study conducted by Smith et al. (2023) revealed that the compound significantly reduces oxidative stress markers in neuronal cells, suggesting potential applications in neurodegenerative diseases such as Alzheimer's and Parkinson's. These findings are particularly noteworthy given the limited therapeutic options currently available for these conditions.

Another promising avenue of research involves the compound's potential as an anticancer agent. Preliminary data from a 2024 study indicate that 5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide inhibits the proliferation of certain cancer cell lines, including breast and lung cancer, by modulating key signaling pathways such as PI3K/AKT and MAPK. While these results are encouraging, further studies are needed to evaluate its efficacy and safety in animal models and human trials.

Despite these advancements, challenges remain in the development of 5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide as a therapeutic agent. Issues such as bioavailability, metabolic stability, and potential off-target effects need to be addressed through rigorous pharmacokinetic and toxicological studies. Collaborative efforts between academia and industry will be essential to overcome these hurdles and translate preclinical findings into clinical applications.

In conclusion, 5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS: 85614-92-2) represents a promising compound with diverse therapeutic potential. Recent research has shed light on its synthesis, pharmacological properties, and mechanisms of action, but further studies are required to fully realize its clinical benefits. As the field continues to evolve, this compound may emerge as a valuable addition to the arsenal of treatments for inflammatory, neurodegenerative, and oncological diseases.

85614-92-2 (5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide) Related Products

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Amadis Chemical Company Limited
(CAS:85614-92-2)5-Methyl-2-oxo-1,2-dihydropyridine-3-carboxamide
A863516
Purity:99%
Quantity:1g
Price ($):472.0
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