Cas no 853955-70-1 ({2-(4-Fluorophenyl)dimethylsilylphenyl}methanol)
{2-(4-Fluorophenyl)dimethylsilylphenyl}methanol is a fluorinated organosilicon compound featuring a hydroxymethyl group and a dimethylsilyl moiety attached to a biphenyl scaffold. Its key structural advantages include the electron-withdrawing 4-fluorophenyl group, which enhances stability and reactivity in synthetic applications. The silyl group offers steric protection and can participate in further functionalization, while the benzylic alcohol provides a versatile handle for derivatization. This compound is particularly useful in organic synthesis, serving as an intermediate for pharmaceuticals, agrochemicals, or advanced materials. Its well-defined structure and functional group compatibility make it valuable for cross-coupling reactions, catalysis, or as a building block in complex molecule assembly.
853955-70-1 structure
Product Name:{2-(4-Fluorophenyl)dimethylsilylphenyl}methanol
CAS No:853955-70-1
MF:C15H17FOSi
MW:260.378788709641
MDL:MFCD16251550
CID:860177
PubChem ID:11989534
Update Time:2025-06-07
{2-(4-Fluorophenyl)dimethylsilylphenyl}methanol Chemical and Physical Properties
Names and Identifiers
-
- 2-[(4-Fluorophenyl)dimethylsilyl]benzyl alcohol
- [2-[(4-fluorophenyl)-dimethylsilyl]phenyl]methanol
- {2-[(4-Fluorophenyl)dimethylsilyl]phenyl}methanol
- HOMSi(R) p-Fluorophenyl [2-[(p-Fluorophenyl)dimethylsilanyl]phenyl]methano
- AMTSi119
- M-1499
- (2-((4-Fluorophenyl)dimethylsilyl)phenyl)methanol
- 853955-70-1
- AS-2211
- {2-[(4-Fluoro-phenyl)-dimethyl-silanyl]-phenyl}-methanol
- SCHEMBL2009165
- {2-[(4-Fluorophenyl)(dimethyl)silyl]phenyl}methanol
- AMTSi119; M-1499
- A917564
- CS-0456378
- MFCD16251550
- DTXSID90475304
- AKOS025392265
- {2-(4-Fluorophenyl)dimethylsilylphenyl}methanol
-
- MDL: MFCD16251550
- Inchi: 1S/C15H17FOSi/c1-18(2,14-9-7-13(16)8-10-14)15-6-4-3-5-12(15)11-17/h3-10,17H,11H2,1-2H3
- InChI Key: RKOHTBFNQRVSEP-UHFFFAOYSA-N
- SMILES: [Si](C)(C)(C1C=CC(=CC=1)F)C1C=CC=CC=1CO
Computed Properties
- Exact Mass: 260.10300
- Monoisotopic Mass: 260.10326986g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 18
- Rotatable Bond Count: 3
- Complexity: 261
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 20.2?2
Experimental Properties
- PSA: 20.23000
- LogP: 2.14060
{2-(4-Fluorophenyl)dimethylsilylphenyl}methanol Security Information
- Signal Word:Warning
- Hazard Statement: H315; H319; H335
- Warning Statement: P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501
- Storage Condition:Store at room temperature
{2-(4-Fluorophenyl)dimethylsilylphenyl}methanol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Apollo Scientific | PC200130-500mg |
{2-[(4-Fluorophenyl)dimethylsilyl]phenyl}methanol |
853955-70-1 | 500mg |
£70.00 | 2023-09-02 | ||
| Apollo Scientific | PC200130-1g |
{2-[(4-Fluorophenyl)dimethylsilyl]phenyl}methanol |
853955-70-1 | 1g |
£80.00 | 2023-09-02 | ||
| Apollo Scientific | PC200130-5g |
{2-[(4-Fluorophenyl)dimethylsilyl]phenyl}methanol |
853955-70-1 | 5g |
£175.00 | 2023-09-02 | ||
| AK Scientific | AMTSi119-100mg |
{2-[(4-Fluoro-phenyl)-dimethyl-silanyl]-phenyl}-methanol |
853955-70-1 | 95% | 100mg |
$94 | 2025-02-18 | |
| AK Scientific | AMTSi119-250mg |
{2-[(4-Fluoro-phenyl)-dimethyl-silanyl]-phenyl}-methanol |
853955-70-1 | 95% | 250mg |
$188 | 2025-02-18 | |
| TRC | B435263-50mg |
{2-[(4-Fluorophenyl)dimethylsilyl]phenyl}methanol |
853955-70-1 | 50mg |
$ 50.00 | 2022-06-07 | ||
| TRC | B435263-100mg |
{2-[(4-Fluorophenyl)dimethylsilyl]phenyl}methanol |
853955-70-1 | 100mg |
$ 65.00 | 2022-06-07 | ||
| TRC | B435263-500mg |
{2-[(4-Fluorophenyl)dimethylsilyl]phenyl}methanol |
853955-70-1 | 500mg |
$ 80.00 | 2022-06-07 | ||
| Key Organics Ltd | AS-2211-5G |
{2-[(4-fluorophenyl)dimethylsilyl]phenyl}methanol |
853955-70-1 | >95% | 5g |
£146.00 | 2025-02-08 | |
| Key Organics Ltd | AS-2211-0.5G |
{2-[(4-fluorophenyl)dimethylsilyl]phenyl}methanol |
853955-70-1 | >95% | 0.5g |
£36.00 | 2025-02-08 |
{2-(4-Fluorophenyl)dimethylsilylphenyl}methanol Related Literature
-
Luis Miguel Azofra,Douglas R. MacFarlane,Chenghua Sun Chem. Commun., 2016,52, 3548-3551
-
Jialiang Yuan,Ran Dong,Yuan Li,Yang Liu,Zhuo Zheng,Yuxia Liu,Yan Sun,Benhe Zhong,Zhenguo Wu,Xiaodong Guo Chem. Commun., 2021,57, 13004-13007
-
Supaporn Sawadjoon,Joseph S. M. Samec Org. Biomol. Chem., 2011,9, 2548-2554
-
Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu Ma RSC Adv., 2021,11, 37631-37642
853955-70-1 ({2-(4-Fluorophenyl)dimethylsilylphenyl}methanol) Related Products
- 1244855-63-7(HOMSiR 2,3-Dimethylphenyl)
- 1266252-11-2(1,4-Bis(HOMSiR)phenyl)
- 1217863-38-1(2-(Dimethyl-p-tolyl-silanyl)-phenylmethanol)
- 853955-69-8(2-(Dimethylphenylsilyl)benzyl alcohol)
- 2055378-48-6(Benzene, 4-fluoro-2-[[(2-methylphenyl)methoxy]methyl]-1-(trimethylsilyl)-)
- 17876-97-0(Benzenemethanol, 2-(trimethylsilyl)-)
- 104230-68-4(Benzenemethanol, 2-(dimethylphenylsilyl)-3,6-dimethyl-)
- 853955-71-2({2-Dimethyl(2-methylphenyl)silylphenyl}methanol)
- 947515-76-6({2-Dimethyl(2,4,6-trimethylphenyl)silylphenyl}methanol)
- 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
Recommended suppliers
Henan Dongyan Pharmaceutical Co., Ltd
Gold Member
CN Supplier
Bulk
ASIACHEM I&E (JIANGSU) CO., LTD
Gold Member
CN Supplier
Bulk
Shanghai Hongxiang Biomedical Technology Co., Ltd.
Gold Member
CN Supplier
Bulk
Shenzhen Jianxing Pharmaceutical Technology Co., Ltd.
Gold Member
CN Supplier
Reagent
Essenoi Fine Chemical Co., Limited
Gold Member
CN Supplier
Reagent