Cas no 85293-12-5 ((3-methoxyphenyl)methylhydrazine)

(3-Methoxyphenyl)methylhydrazine is a hydrazine derivative featuring a methoxy-substituted phenyl ring, offering utility as a versatile intermediate in organic synthesis. Its structure enables selective functionalization, making it valuable for the preparation of pharmaceuticals, agrochemicals, and specialty chemicals. The methoxy group enhances solubility and reactivity in certain reaction conditions, while the hydrazine moiety serves as a key building block for heterocycle formation, such as indoles or pyrazoles. This compound is particularly useful in nucleophilic addition and condensation reactions. Careful handling is advised due to the potential reactivity of hydrazine derivatives. Its stability and well-defined properties make it a reliable choice for research and industrial applications.
(3-methoxyphenyl)methylhydrazine structure
85293-12-5 structure
Product Name:(3-methoxyphenyl)methylhydrazine
CAS No:85293-12-5
MF:C8H12N2O
MW:152.193681716919
MDL:MFCD11983253
CID:707878
PubChem ID:2760980
Update Time:2026-04-29

(3-methoxyphenyl)methylhydrazine Chemical and Physical Properties

Names and Identifiers

    • (3-Methoxybenzyl)hydrazine
    • 1-(3-methoxybenzyl)hydrazine
    • 3-Methoxybenzylhydrazine dihydrochloride
    • Hydrazine,[(3-methoxyphenyl)methyl]-
    • (3-methoxybenzyl)hydrazine(SALTDATA: HCl)
    • [(3-Methoxyphenyl)methyl]hydrazine
    • 3-methoxybenzylhydrazine
    • hydrazine,[(3-methoxyphenyl)methyl]
    • (3-methoxyphenyl)methylhydrazine
    • MDL: MFCD11983253
    • Inchi: InChI=1S/C8H12N2O/c1-11-8-4-2-3-7(5-8)6-10-9/h2-5,10H,6,9H2,1H3
    • InChI Key: UPLGQRHDYAHDRC-UHFFFAOYSA-N
    • SMILES: COC1=CC=CC(=C1)CNN

Computed Properties

  • Exact Mass: 152.09500
  • Monoisotopic Mass: 152.095
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 3
  • Complexity: 108
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.7
  • Topological Polar Surface Area: 47.3A^2

Experimental Properties

  • Density: 1.069
  • Melting Point: 116-118°C
  • Boiling Point: 311 oC
  • Flash Point: 142 oC
  • Refractive Index: 1.545
  • PSA: 47.28000
  • LogP: 1.74970

(3-methoxyphenyl)methylhydrazine Security Information

  • Hazardous Material Identification: Xi
  • HazardClass:IRRITANT

(3-methoxyphenyl)methylhydrazine Customs Data

  • HS CODE:2928000090
  • Customs Data:

    China Customs Code:

    2928000090

    Overview:

    2928000090 Other hydrazine(Hydrazine)And chlorhexidine(hydroxylamine)Organic derivatives of.Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:6.5%.general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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(3-methoxyphenyl)methylhydrazine Suppliers

Amadis Chemical Company Limited
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(CAS:85293-12-5)(3-methoxyphenyl)methylhydrazine
Order Number:A863618
Stock Status:in Stock
Quantity:1g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 08:42
Price ($):512.0

Additional information on (3-methoxyphenyl)methylhydrazine

Introduction to (3-methoxyphenyl)methylhydrazine (CAS No. 85293-12-5)

(3-methoxyphenyl)methylhydrazine, with the CAS number 85293-12-5, is a significant compound in the field of organic chemistry and pharmaceutical research. This compound, featuring a methoxy group on the phenyl ring and a hydrazine moiety, has garnered attention due to its versatile applications in synthetic chemistry and potential roles in drug development.

The structure of (3-methoxyphenyl)methylhydrazine consists of a benzene ring substituted with a methoxy group at the 3-position and an N-methylhydrazine side chain. This particular arrangement imparts unique chemical properties that make it valuable in various chemical transformations. The presence of both electron-donating and electron-withdrawing groups on the aromatic ring allows for selective reactions, making it a useful intermediate in the synthesis of more complex molecules.

In recent years, research into (3-methoxyphenyl)methylhydrazine has expanded significantly, particularly in the context of medicinal chemistry. Its hydrazine group is known to participate in various functionalization reactions, including condensation reactions with carbonyl compounds to form hydrazones. These hydrazones have been explored as precursors for more complex pharmacophores, contributing to the development of new therapeutic agents.

One of the most intriguing aspects of (3-methoxyphenyl)methylhydrazine is its potential as a building block for biologically active compounds. Studies have demonstrated its utility in constructing heterocyclic scaffolds, which are prevalent in many drugs. For instance, derivatives of this compound have been investigated for their antimicrobial and anti-inflammatory properties. The methoxy group on the phenyl ring can be further modified through various chemical pathways, allowing for the creation of diverse molecular structures with tailored biological activities.

The synthesis of (3-methoxyphenyl)methylhydrazine typically involves multi-step organic reactions, starting from commercially available aromatic precursors. The process often requires careful control of reaction conditions to ensure high yield and purity. Advances in synthetic methodologies have enabled more efficient and scalable production methods, making this compound more accessible for research purposes.

In the realm of computational chemistry, (3-methoxyphenyl)methylhydrazine has been studied to understand its electronic properties and reactivity. Molecular modeling techniques have provided insights into how the compound interacts with other molecules, which is crucial for designing effective drugs. These computational studies help predict potential side effects and optimize drug candidates before they enter clinical trials.

The pharmaceutical industry has shown particular interest in (3-methoxyphenyl)methylhydrazine due to its potential as a scaffold for novel therapeutics. Researchers are exploring its derivatives as candidates for treating various diseases, including neurological disorders and cancer. The hydrazine moiety's ability to form stable bonds with other functional groups makes it a valuable component in drug design.

Ethical considerations are also important when researching compounds like (3-methoxyphenyl)methylhydrazine. Ensuring that synthetic pathways are environmentally sustainable and that research is conducted responsibly are key priorities. Collaborative efforts between academia and industry are essential to drive innovation while maintaining high ethical standards.

The future of (3-methoxyphenyl)methylhydrazine research looks promising, with ongoing studies aimed at uncovering new applications and improving synthetic methods. As our understanding of organic chemistry evolves, so too will the ways in which this compound is utilized. Continued investment in research and development will be crucial to realizing its full potential in pharmaceuticals and beyond.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:85293-12-5)(3-methoxyphenyl)methylhydrazine
A863618
Purity:99%
Quantity:1g
Price ($):512.0
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