• 1. Enabling high-throughput single-animal gene-expression studies with molecular and micro-scale technologies
  Jason Wan Lab Chip, 2020,20, 4528-4538
• 2. Emerging investigator series: first-principles and thermodynamics comparison of compositionally-tuned delafossites: cation release from the (001) surface of complex metal oxides?
  Joseph W. Bennett,Diamond T. Jones,Blake G. Hudson,Joshua Melendez-Rivera,Robert J. Hamers,Sara E. Mason Environ. Sci.: Nano, 2020,7, 1642-1651
• 3. Emerging 2D hybrid nanomaterials: towards enhanced sensitive and selective conductometric gas sensors at room temperature
  Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
• 4. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?
  Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
• 5. Exceptional activity of sub-nm Pt clusters on CdS for photocatalytic hydrogen production: a combined experimental and first-principles study?
  Qiyuan Wu,Shangmin Xiong,Peichuan Shen,Shen Zhao,Alexander Orlov Catal. Sci. Technol., 2015,5, 2059-2064

Introduction to 2-Phenoxy-N-methylethylamine Hydrochloride (CAS No. 85262-76-6)

2-Phenoxy-N-methylethylamine hydrochloride, also known by its CAS registry number CAS No. 85262-76-6, is a compound of significant interest in the fields of organic chemistry and pharmacology. This compound is a derivative of phenoxyethylamine, with a methoxy group attached to the nitrogen atom, forming a tertiary amine structure. The hydrochloride salt form is commonly used in pharmaceutical applications due to its enhanced solubility and stability.

The molecular structure of 2-Phenoxy-N-methylethylamine hydrochloride consists of a phenyl group attached to an oxygen atom, which is further connected to an ethyl chain. The ethyl chain terminates with an amine group that is methylated, forming a tertiary amine. The hydrochloride salt is formed by the reaction of this amine with hydrochloric acid, resulting in a crystalline solid that is highly soluble in water.

Recent studies have highlighted the potential of 2-Phenoxy-N-methylethylamine hydrochloride as a precursor in the synthesis of various bioactive compounds. For instance, researchers have explored its role in the development of novel antidepressants and anxiolytics, leveraging its structural similarity to known neurotransmitter modulators. The compound's ability to interact with serotonin and dopamine receptors has been a focal point in recent pharmacological investigations.

In terms of synthesis, 2-Phenoxy-N-methylethylamine hydrochloride can be prepared through a variety of methods, including nucleophilic substitution and amine alkylation reactions. One common approach involves the reaction of phenoxyethyl alcohol with methylamine in the presence of an acid catalyst, followed by acidification to isolate the hydrochloride salt. This method ensures high purity and yield, making it suitable for large-scale production.

The physical properties of 2-Phenoxy-N-methylethylamine hydrochloride include a melting point of approximately 180°C and a boiling point around 300°C under standard conditions. Its solubility in water is significantly higher compared to its free base form, which facilitates its use in aqueous-based pharmaceutical formulations.

In addition to its pharmaceutical applications, 2-Phenoxy-N-methylethylamine hydrochloride has shown promise in the field of agrochemicals. Recent research has demonstrated its potential as a plant growth regulator, capable of enhancing crop yields under stress conditions such as drought or high salinity. This application underscores the compound's versatility and broad utility across multiple industries.

The environmental impact of 2-Phenoxy-N-methylethylamine hydrochloride has also been a subject of recent studies. Researchers have investigated its biodegradability and toxicity profiles, with findings indicating that it undergoes rapid microbial degradation under aerobic conditions. This makes it an environmentally friendly option for certain industrial applications compared to more persistent chemicals.

In conclusion, 2-Phenoxy-N-methylethylamine hydrochloride (CAS No. 85262-76-6) is a multifaceted compound with applications spanning pharmaceuticals, agrochemicals, and materials science. Its unique chemical structure and favorable physicochemical properties make it an invaluable tool for researchers and industry professionals alike. As ongoing research continues to uncover new potential uses for this compound, its significance in various fields is expected to grow further.

• 915921-56-1(2-(3-Ethoxyphenoxy)-N-methylethanamine)
• 13468-02-5(N,N-Dimethyl-2-phenoxyethanamine)
• 37421-04-8(N-Methyl-2-phenoxyethanamine)
• 91251-54-6(N-Ethyl-2-phenoxyethanamine)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)