Cas no 848482-93-9 ((2S)-4-tert-butoxycarbonylpiperazine-2-carboxylic acid)

(2S)-4-tert-Butoxycarbonylpiperazine-2-carboxylic acid is a chiral piperazine derivative widely utilized as a key intermediate in pharmaceutical synthesis and peptide chemistry. Its tert-butoxycarbonyl (Boc) protecting group ensures selective reactivity, enabling controlled deprotection under mild acidic conditions. The stereospecific (2S) configuration is critical for applications requiring enantiopure compounds, such as drug development and asymmetric synthesis. This compound exhibits high purity and stability, making it suitable for complex organic transformations. Its carboxylic acid functionality allows further derivatization, facilitating the construction of peptidomimetics and bioactive molecules. The Boc group also enhances solubility in organic solvents, streamlining purification processes. This reagent is valued for its reliability in medicinal chemistry and peptide research.

(2S)-4-tert-butoxycarbonylpiperazine-2-carboxylic acid structure

848482-93-9 structure

Product Name:(2S)-4-tert-butoxycarbonylpiperazine-2-carboxylic acid

CAS No:848482-93-9

MF:C₁₀H₁₈N₂O₄

MW:230.260922908783

MDL:MFCD02179098

CID:68947

PubChem ID:1501850

Update Time:2025-06-09

(2S)-4-tert-butoxycarbonylpiperazine-2-carboxylic acid Chemical and Physical Properties

Names and Identifiers

- (S)-1-Boc-Piperazine-3-carboxylic acid
- (S)-4-(tert-Butoxycarbonyl)piperazine-2-carboxylic acid
- (S)-4-N-Boc-Piperazine-2-Carboxylic Acid
- 4-Boc-piperazine-2-(S)-carboxylic acid
- (S)-4-Boc-2-piperazinecarboxylic acid
- (S)-4-Boc-Piperazine-2-carboxylic acid
- (S)-4-N-tert-butoxycarbonylpiperazine-2-carboxylic acid
- (S)-piperazine-1,3-dicarboxylic acid 1-tert-butyl ester
- 1,3-Piperazinedicarboxylic acid,1-(1,1-dimethylethyl) ester,(3S)
- 4-Boc-pip
- 4-boc-piperazine-2-carboxylic acid
- s-bpca
- (S)-4-(tert-Butoxylcarbonyl)-piperazine-2-carboxylic acid
- (2S)-4-tert-butoxycarbonylpiperazine-2-carboxylic acid
- 1-(1,1-Dimethylethyl) (3S)-1,3-piperazinedicarboxylate (ACI)
- (2S)-4-[(2-Methylpropan-2-yl)oxycarbonyl]piperazin-1-ium-2-carboxylate
- (2S)-4-[(tert-Butoxy)carbonyl]piperazine-2-carboxylic acid
- DB-031467
- AKOS015897888
- Q-102961
- 1,3-Piperazinedicarboxylicacid, 1-(1,1-dimethylethyl) ester, (3S)-
- DTXSID70363538
- C10H18N2O4
- (S)-4-N-Boc-piperazine-2-carboxylic acid, AldrichCPR
- TS-00607
- (2S)-4-(TERT-BUTOXYCARBONYL)PIPERAZINE-2-CARBOXYLIC ACID
- (S)-4-(tert-butoxycarbonyl) piperazine-2-carboxylic acid
- (s)-1,3-piperazinedicarboxylic acid, 1-(1,1-dimethylethyl) ester
- YRYAXQJXMBETAT-ZETCQYMHSA-N
- SCHEMBL1184732
- MFCD02179098
- (2S)-4-[(2-methylpropan-2-yl)oxycarbonyl]piperazine-2-carboxylic acid
- AKOS007930656
- 1,3-Piperazinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (3S)-
- 848482-93-9
- AS-81038
- CS-0001877
- AC-2200
- MDL： MFCD02179098
- Inchi： 1S/C10H18N2O4/c1-10(2,3)16-9(15)12-5-4-11-7(6-12)8(13)14/h7,11H,4-6H2,1-3H3,(H,13,14)/t7-/m0/s1
- InChI Key： YRYAXQJXMBETAT-ZETCQYMHSA-N
- SMILES： C(N1CCN[C@H](C(=O)O)C1)(=O)OC(C)(C)C

Computed Properties

Exact Mass: 230.12700
Monoisotopic Mass: 230.127
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 6
Heavy Atom Count: 16
Rotatable Bond Count: 4
Complexity: 285
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 1
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 78.9A^2
XLogP3: -2.2

Experimental Properties

Color/Form: White to Yellow Solid
Density: 1.193
Melting Point: 231-239oC
Boiling Point: 371.8℃ at 760 mmHg
Flash Point: 178.6℃
PSA: 78.87000
LogP: 0.54660

(2S)-4-tert-butoxycarbonylpiperazine-2-carboxylic acid Security Information

Signal Word：Warning
Hazard Statement： H317;H319
Warning Statement： P280;P305+P351+P338
Hazard Category Code： R36: eye irritation. R43:Skin contact can cause allergic reactions.
Safety Instruction： S26-S36/37
Hazardous Material Identification：
Storage Condition：Room temperature
Risk Phrases：R36; R43

(2S)-4-tert-butoxycarbonylpiperazine-2-carboxylic acid Customs Data

HS CODE：2933599090
Customs Data：

China Customs Code:
2933599090

Overview:

2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

Declaration elements:

Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

Summary:

2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

(2S)-4-tert-butoxycarbonylpiperazine-2-carboxylic acid Pricemore >>

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Fluorochem	034387-1g	S)-4-N-Boc-Piperazine-2-carboxylic acid	848482-93-9	97%	1g	￡44.00	2022-03-01
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(2S)-4-tert-butoxycarbonylpiperazine-2-carboxylic acid Production Method

(2S)-4-tert-butoxycarbonylpiperazine-2-carboxylic acid Suppliers

NewCan Biotech Limited

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Audited Supplier

(CAS:848482-93-9)(S)-4-N-Boc-piperazine-2-carboxylic acid

Order Number:NC15679

Stock Status:

Quantity:10g

Purity:97%

Pricing Information Last Updated:Friday, 18 July 2025 16:01

Price ($):Price inquiry

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