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Professional Introduction to Methyl 2-(ethylamino)acetate (CAS No. 84532-85-4)

Methyl 2-(ethylamino)acetate, a compound with the chemical formula C6H11NO2 and the CAS number 84532-85-4, is a significant molecule in the field of organic chemistry and pharmaceutical research. This ester derivative exhibits unique structural and functional properties that make it valuable in various applications, particularly in the synthesis of bioactive molecules and as an intermediate in drug development.

The compound is characterized by a methyl ester group attached to an acetic acid moiety, which is further substituted with an ethylamino group. This structural configuration imparts a high degree of reactivity, making it a versatile building block in synthetic chemistry. The presence of both an amine and an ester functionality allows for diverse chemical transformations, including nucleophilic substitutions, condensations, and reductions, which are pivotal in constructing more complex molecular frameworks.

In recent years, the pharmaceutical industry has shown increasing interest in methyl 2-(ethylamino)acetate due to its potential as a precursor in the synthesis of novel therapeutic agents. Its structural features are reminiscent of several bioactive scaffolds found in drugs used to treat neurological disorders, cardiovascular diseases, and inflammatory conditions. Researchers have been exploring its utility in generating derivatives with enhanced pharmacological properties.

One of the most compelling aspects of methyl 2-(ethylamino)acetate is its role in the development of enzyme inhibitors. The ethylamino group can interact with specific binding pockets on enzymes, modulating their activity. For instance, studies have demonstrated its potential in inhibiting acetylcholinesterase, an enzyme crucial for cognitive function and implicated in neurodegenerative diseases such as Alzheimer's. The methyl ester group also provides a handle for further functionalization, allowing chemists to tailor the molecule for optimal biological activity.

The synthesis of methyl 2-(ethylamino)acetate typically involves the reaction of ethylammonia with ethyl acetoacetate or similar β-keto esters under controlled conditions. Advances in catalytic methods have improved the efficiency and yield of these reactions, making the compound more accessible for large-scale applications. Additionally, green chemistry principles have been applied to develop more sustainable synthetic routes, reducing waste and energy consumption.

Recent research has also highlighted the compound's significance in material science. Methyl 2-(ethylamino)acetate has been investigated as a monomer or co-monomer in polymer synthesis, where its ability to form hydrogen bonds contributes to the development of materials with unique mechanical and thermal properties. These materials find applications in coatings, adhesives, and even biodegradable plastics.

The compound's solubility profile is another area of interest. Methyl 2-(ethylamino)acetate exhibits good solubility in both polar and non-polar solvents, making it adaptable for various solution-based processes such as crystallization and chromatography. This property is particularly advantageous in pharmaceutical formulations where solvent compatibility is critical for drug delivery systems.

In conclusion, methyl 2-(ethylamino)acetate (CAS No. 84532-85-4) is a multifaceted compound with broad applications across multiple scientific disciplines. Its structural features enable diverse chemical transformations, making it indispensable in pharmaceutical research and industrial chemistry. As our understanding of molecular interactions deepens, the potential uses for this compound are likely to expand further, solidifying its importance as a key intermediate in modern chemistry.

• 62491-02-5(Glycine, N-(2-methoxy-2-oxoethyl)-, methyl ester, dihydrochloride)
• 39987-25-2(Dimethyl iminodiacetate hydrochloride)
• 61532-99-8(Ethanaminium, N,N-diethyl-2-methoxy-N-(2-methoxy-2-oxoethyl)-2-oxo-)
• 1121527-61-4(Ethylamino-acetic Acid Methyl Ester Hydrochloride)
• 6096-81-7(Glycine, N-(2-methoxy-2-oxoethyl)-, methyl ester)
• 30280-35-4(N,N-Diethylglycine Methyl Ester)
• 13515-93-0(methyl 2-(methylamino)acetate;hydrochloride)
• 6290-05-7(Diethyl iminodiacetate)
• 5473-12-1(methyl 2-(methylamino)acetate)
• 61532-98-7(Ethanaminium,2-methoxy-N-(2-methoxy-2-oxoethyl)-N,N-dimethyl-2-oxo-)