• 1. Dissolved oxygen sensor based on fluorescence quenching of oxygen-sensitive ruthenium complexes immobilized in sol–gel-derived porous silica coatings
  Analyst, 1996,121, 785-788
• 2. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
• 3. Emulsion technologies for multicellular tumour spheroid radiation assays?
  Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
• 4. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
• 5. Enabling high-throughput single-animal gene-expression studies with molecular and micro-scale technologies
  Jason Wan Lab Chip, 2020,20, 4528-4538

• Solvents and Organic Chemicals Organic Compounds Organohalogen compounds Alkyl halides Cyclohexyl halides

Comprehensive Guide to (1-Chlorocyclohexyl)cyclohexyl-methanone (CAS 83803-75-2): Properties, Applications, and Market Insights

(1-Chlorocyclohexyl)cyclohexyl-methanone (CAS 83803-75-2) is a specialized organic compound that has garnered significant attention in recent years due to its unique chemical structure and versatile applications. As researchers and industries continue to explore novel compounds for various scientific and industrial purposes, this particular ketone derivative has emerged as a subject of interest. Its molecular formula, C₁₃H₂₁ClO, reveals a chlorinated cyclohexyl structure that contributes to its distinct properties.

The compound's physical and chemical characteristics make it valuable for multiple applications. With a molecular weight of 228.76 g/mol, (1-Chlorocyclohexyl)cyclohexyl-methanone typically appears as a colorless to pale yellow liquid or low-melting solid at room temperature. Its boiling point and melting point vary depending on purity and environmental conditions, which is crucial information for researchers working with this material. The presence of both chlorine and carbonyl functional groups in its structure enables diverse reactivity patterns, making it a valuable intermediate in organic synthesis.

In the pharmaceutical sector, (1-Chlorocyclohexyl)cyclohexyl-methanone serves as a key building block for the synthesis of more complex molecules. Recent studies have explored its potential as a precursor in developing central nervous system (CNS) active compounds, particularly those targeting neurological disorders—a hot topic in current medical research. The compound's structural flexibility allows medicinal chemists to modify its framework to create derivatives with specific biological activities.

The material science field has also shown growing interest in CAS 83803-75-2 for polymer modification applications. Its ability to act as a cross-linking agent or chain modifier makes it valuable in creating specialty polymers with enhanced thermal stability or mechanical properties. This application aligns with the current industry focus on developing advanced materials for electronics, coatings, and high-performance composites.

From a synthetic chemistry perspective, (1-Chlorocyclohexyl)cyclohexyl-methanone offers interesting possibilities for nucleophilic substitution reactions at the chlorine-bearing carbon center. The adjacent carbonyl group can influence the reactivity, enabling selective transformations that are valuable in constructing complex molecular architectures. These characteristics make it particularly relevant to researchers working on asymmetric synthesis and catalysis—areas receiving substantial attention in contemporary organic chemistry.

The global market for specialty ketones like (1-Chlorocyclohexyl)cyclohexyl-methanone has shown steady growth, driven by increasing demand from pharmaceutical and advanced materials sectors. Market analysts note particular interest from Asia-Pacific regions, where chemical innovation hubs are expanding rapidly. Pricing trends for this compound reflect its niche status, with purity levels and quantity significantly affecting cost structures.

Environmental and safety considerations for handling 83803-75-2 follow standard laboratory protocols for organic compounds. Proper personal protective equipment (PPE) including gloves and eye protection is recommended when working with this material. Storage typically requires cool, dry conditions in tightly sealed containers to maintain stability—a common query among first-time users of this compound.

Recent advancements in green chemistry have prompted investigations into more sustainable synthesis routes for (1-Chlorocyclohexyl)cyclohexyl-methanone. Researchers are exploring catalytic methods and alternative solvents to reduce the environmental impact of its production. These developments align with the chemical industry's broader shift toward eco-friendly manufacturing processes—a major focus area in current chemical research.

Analytical characterization of CAS 83803-75-2 typically involves techniques such as nuclear magnetic resonance (NMR) spectroscopy, infrared (IR) spectroscopy, and mass spectrometry. The compound's distinct spectral signatures facilitate quality control and purity assessment, which are critical for research and industrial applications. These analytical aspects represent frequent search topics among chemists working with this material.

Future research directions for (1-Chlorocyclohexyl)cyclohexyl-methanone may explore its potential in emerging fields like metal-organic frameworks (MOFs) or as a ligand in coordination chemistry. The compound's structural features suggest possible applications in these cutting-edge areas, which are currently among the most searched topics in materials science and inorganic chemistry.

For researchers considering working with 83803-75-2, several commercial suppliers offer this compound in varying purity grades. Procurement considerations should include evaluation of certificates of analysis (CoA), packaging options, and supplier reliability—factors that frequently appear in search queries related to chemical purchasing decisions. The compound's availability in smaller research quantities has increased in recent years, reflecting growing academic interest.

In conclusion, (1-Chlorocyclohexyl)cyclohexyl-methanone represents an interesting case study in how specialty organic compounds can find applications across multiple scientific disciplines. Its combination of structural features and chemical reactivity continues to attract research attention, particularly in fields addressing current challenges in healthcare and advanced materials. As synthetic methodologies advance and application areas expand, this compound will likely remain relevant in chemical research and development landscapes.

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)