Cas no 83380-47-6 (OFLOXACIN)

OFLOXACIN structure
OFLOXACIN structure
Product Name:OFLOXACIN
CAS No:83380-47-6
MF:C18H20FN3O4
MW:361.36750793457
CID:826850
PubChem ID:4583
Update Time:2025-04-19

OFLOXACIN Chemical and Physical Properties

Names and Identifiers

    • OFLOXACIN
    • TARIVID
    • 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (?à)-
    • (?à)-Ofloxacin
    • 9-Fluoro-2,3-dihydro-3-methyl-10-(N-methylpiperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid
    • 9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid
    • DL 8280
    • Exocin
    • Flobacin
    • Floxal
    • Floxil
    • Floxin
    • HOE 280
    • Kirol
    • Meneflox
    • ORF 18489
    • Ocuflox
    • Oflin
    • Oflocet
    • Oflocin
    • Ofloren
    • Oflovir
    • Oflox
    • Ofloxacine
    • Ofloxin
    • Ofxin
    • Olfo 200
    • Oxaldin
    • PT 01
    • Prifloxcin
    • Prifloxin
    • Surnor
    • Tariferid
    • Tarivan
    • Visiren
    • Visren
    • WP 0405
    • Zanocin
    • HMS2092B10
    • NCGC00015772-04
    • 8-Methyl-2,3-dihydrofuro[3,2-e]imidazo-[1,2-c]pyrimidine-9-carboxylicacid
    • Prestwick2_000237
    • VU0243192-7
    • NCGC00015772-07
    • NCGC00015772-13
    • NSC-727071
    • Ofloxacino
    • NCGC00094219-02
    • 9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido [1,2,3-de]-1,4-Benzoxazin-6-carboxylic Acid
    • 9-Fluoro-3,7-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid
    • CAS-82419-36-1
    • SR-01000076050-1
    • NS00098749
    • AB00052263-13
    • 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
    • FLOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER
    • (+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
    • HMS3259G07
    • Ofloxacin, VETRANAL(TM), analytical standard
    • NSC 758178
    • NCGC00094219-01
    • 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid
    • DL-ofloxacin
    • 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-
    • HMS502E03
    • NCGC00094219-06
    • OFLOXACIN [VANDF]
    • SCHEMBL24373
    • Pharmakon1600-01502044
    • NCGC00015772-12
    • 1ST5740
    • Ofloxacin (USAN:USP:INN:BAN:JAN)
    • Ofloxaxin
    • NCGC00016948-01
    • DL8280
    • MLS000028749
    • SY052697
    • KBio1_000721
    • 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
    • Tox21_110703
    • OFLOXACIN [USAN]
    • Ofloxacin, Pharmaceutical Secondary Standard; Certified Reference Material
    • 82419-36-1
    • 9-FLUORO-2,3-DIHYDRO-3-METHYL-10-(4-METHYL-1-PIPERAZINYL)-7-OXO-7H-PYRIDO(1,2,3-DE)(1,4)BENZOXAZINE-6-CARBOXYLIC ACID, DL-
    • Prestwick3_000237
    • DL-8280
    • EU-0100904
    • SR-01000076050
    • FT-0627808
    • Spectrum5_001063
    • NCGC00094219-04
    • FT-0673216
    • CCRIS 5233
    • Z56761309
    • NCGC00178284-02
    • Ofloxacine [French]
    • 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0,5,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
    • HMS3712P15
    • SY007392
    • HMS3393K06
    • BSPBio_003117
    • Ofloxacin [USAN:USP:INN:BAN:JAN]
    • Monoflocet
    • Tox21_110703_1
    • Prestwick0_000237
    • WP-0405
    • (S)-Ofloxacin;Levaquin;Quixin
    • RKL10083
    • KS-5011
    • SDCCGSBI-0050879.P004
    • SR-01000076050-16
    • CHEMBL4
    • BSPBio_000313
    • Tox21_500904
    • Spectrum2_001464
    • BCP14346
    • Ofloxacine; DL-8280; HOE-280
    • J01MA01
    • OFLX
    • SPBio_001387
    • Exocine
    • 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylicacid
    • NCGC00015772-10
    • HMS1568P15
    • Olfoxacin Otic Soln
    • Levofloxacin-13C-D3
    • UNII-A4P49JAZ9H
    • Ofloxacinum [Latin]
    • NCGC00015772-05
    • FLOXIN IN DEXTROSE 5%
    • 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
    • 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
    • (+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazin-6-carbonsaeure
    • HMS1921H12
    • 7-Chloro-4-hydroxy-8-methylquinoline-3-carboxylicethylester
    • NCGC00015772-22
    • NCGC00015772-02
    • NCGC00261589-01
    • Ofloxacinum (Latin)
    • HY-B0125
    • SBI-0050879.P003
    • SCHEMBL14163982
    • AMY22220
    • DTXSID3041085
    • (3RS)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-pyrido(1,2,3-de)(1,4)benzoxazine-6-carboxylic acid
    • DivK1c_000721
    • SPBio_002234
    • CCG-39210
    • NCGC00015772-08
    • MFCD00865049
    • Ofloxacin, Antibiotic for Culture Media Use Only
    • EN300-06482
    • A4P49JAZ9H
    • OFLOXACIN (USP-RS)
    • OFLOXACIN [WHO-DD]
    • KBio3_002617
    • MLS001074203
    • AB00052263_14
    • SPECTRUM1502044
    • Q411447
    • Hoe-280
    • Floxin (TN)
    • Ofloxacin Otic
    • fluoro-methyl-(4-methylpiperazin-1-yl)-oxo-[?]carboxylic acid
    • Exocin (eye drops)
    • MLS006011774
    • (+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
    • Ofloxacina [DCIT]
    • 7H-PYRIDO(1,2,3-DE)-1,4-BENZOXAZINE-6-CARBOXYLIC ACID, 9-FLUORO-2,3-DIHYDRO-3-METHYL-10-(4-METHYL-1-PIPERAZINYL)-7-OXO-, (+/-)-
    • (3R)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
    • SMR000058192
    • OFLOXACIN [EP MONOGRAPH]
    • Ofloxacinum
    • Opera_ID_1114
    • IDI1_000721
    • Floxin otic
    • AKOS016042783
    • HMS3262F10
    • AB00052263_15
    • OFLOXACIN (MART.)
    • GTPL10918
    • NCGC00015772-09
    • Ofloxacin (Floxin)
    • Spectrum_001186
    • AB00052263-12
    • (-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1;(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1
    • O-2800
    • OFLOXACIN [MART.]
    • CHEBI:194135
    • NCGC00015772-06
    • OFLOXACIN [JAN]
    • Prestwick1_000237
    • DTXCID1021085
    • AC-7616
    • HSDB 8030
    • KBio2_004234
    • HMS2235C05
    • AB00513820
    • KBio2_001666
    • 9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid
    • NCGC00178284-01
    • F0472-0226
    • HMS2090F07
    • 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (+-)-
    • DB01165
    • Ofloxacin,(S)
    • NC00466
    • Spectrum4_000324
    • OFLOXACIN [USP-RS]
    • NCGC00094219-03
    • 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (+-)-
    • BRD-A24228527-001-19-0
    • O0403
    • OFLOXACIN [INN]
    • AKOS001033517
    • MFCD00226105
    • BPBio1_000345
    • 1261398-33-7
    • Dextrofloxacin
    • OFX
    • O 8757
    • F0020-0095
    • D00453
    • (+/-)-9-Fluoro-2, 3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
    • GSDSWSVVBLHKDQ-UHFFFAOYSA-N
    • 7-Fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5,7,9(13),11-tetraene-11-carboxylic acid
    • KBio2_006802
    • OFLOXACIN [ORANGE BOOK]
    • NSC-758178
    • (+/-)-9-Fluoro-2,2,3-de)-1,4-benzoxazine-6-carboxylic acid
    • BCP22048
    • Ofloxacin, United States Pharmacopeia (USP) Reference Standard
    • S01AE01
    • Ofloxacin, fluoroquinolone antibiotic
    • 83380-47-6
    • NSC 727071
    • NSC727071
    • OFLOXACIN (USP MONOGRAPH)
    • NCGC00094219-05
    • s1463
    • Ofloxacino [Spanish]
    • BRD-A24228527-001-05-9
    • FT-0670773
    • Ofloxacin, European Pharmacopoeia (EP) Reference Standard
    • Ofloxacin (JP17/USP/INN)
    • Ofloxacina
    • Ofloxacin 100 microg/mL in Acetonitrile
    • Epitope ID:116889
    • OFLOXACIN [MI]
    • KBioGR_000667
    • NCGC00015772-03
    • Ofloxacin Ophth Soln
    • NSC758178
    • HMS3369B01
    • SR-01000076050-4
    • Spectrum3_001499
    • OFLOXACIN [USP MONOGRAPH]
    • LP00904
    • 9-fluoro-3-methyl-10-(4-methylpiperazino)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
    • Ofloxacin Ophthalmic
    • KBioSS_001666
    • BCP9000851
    • CS-1891
    • SR-01000076050-7
    • CHEBI:7731
    • (+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7--oxo-7H-pyrido(1,2,3-de)--1,4-benzoxazine-6-carboxylic acid
    • Oprea1_242882
    • BDBM50045004
    • 138199-71-0 (0.5H2O)
    • Lopac0_000904
    • OFLOXACIN (EP MONOGRAPH)
    • HMS3604B17
    • 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-(1,4)oxazino(2,3,4-ij)quinoline-6-carboxylic acid
    • S02AA16
    • NINDS_000721
    • HMS2095P15
    • FT-0630905
    • BRN 3657947
    • C07321
    • A864414
    • (+/-)-Floxin
    • Inchi： 1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)
    • InChI Key： GSDSWSVVBLHKDQ-UHFFFAOYSA-N
    • SMILES： FC1C=C2C(C(C(=O)O)=CN3C2=C(C=1N1CCN(C)CC1)OCC3C)=O

Computed Properties

  • Exact Mass: 361.144
  • Monoisotopic Mass: 361.144
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 8
  • Heavy Atom Count: 26
  • Rotatable Bond Count: 2
  • Complexity: 634
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: _0.4
  • Topological Polar Surface Area: 73.3A^2

Experimental Properties

  • Density: 1.48
  • Melting Point: [254]
  • Boiling Point: 571.5°Cat760mmHg
  • Flash Point: 299.4°C
  • Refractive Index: 1.669
  • LogP: log Kow = -0.39

OFLOXACIN Security Information

  • WGK Germany：2
  • Safety Instruction： 22-24/25
  • RTECS：UU8815500
  • Storage Condition：2-8°C

OFLOXACIN Related Literature

Related Categories

83380-47-6 (OFLOXACIN) Related Products

Recommended suppliers
TAIXING JOXIN BIO-TEC CO.,LTD.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
TAIXING JOXIN BIO-TEC CO.,LTD.
Nantong Boya Environmental Protection Technology Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Nantong Boya Environmental Protection Technology Co., Ltd
Shandong Feiyang Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Feiyang Chemical Co., Ltd
Shandong Jing Kun Chemical Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Jing Kun Chemical Co.,Ltd.
Zhejiang Brunova Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Zhejiang Brunova Technology Co., Ltd.