• 1. Dissociation of aryl sulfonyl phthalimide radical anions: relevance to the biological activity of arylsulfonyl amides?
  Abdelaziz Houmam,Emad M. Hamed Chem. Commun., 2012,48, 11328-11330
• 2. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
• 3. Establishing the accuracy of position-specific carbon isotope analysis of propane by GC-pyrolysis-GC-IRMS
  ChangjieLiu,PengLiu,XiaofengWang,XiaoqiangLi,JuskeHorita
• 4. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
  Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
• 5. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Benzoic acids

4-(Allyloxy)-3-ethoxybenzoic Acid (CAS No. 831198-97-1): An Overview of Its Properties, Applications, and Recent Research

4-(Allyloxy)-3-ethoxybenzoic acid (CAS No. 831198-97-1) is a versatile organic compound that has garnered significant attention in the fields of chemistry, biology, and pharmaceuticals. This compound is characterized by its unique structural features, which include an allyloxy group and an ethoxy group attached to a benzene ring. These functional groups contribute to its diverse chemical properties and potential applications in various scientific and industrial domains.

The molecular formula of 4-(Allyloxy)-3-ethoxybenzoic acid is C₁₂H₁₄O₄, and its molecular weight is approximately 222.23 g/mol. The compound is a white crystalline solid at room temperature and is soluble in common organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO). Its solubility in water is limited, which can be advantageous in certain applications where controlled solubility is required.

In the realm of organic synthesis, 4-(Allyloxy)-3-ethoxybenzoic acid serves as a valuable building block for the synthesis of more complex molecules. The presence of the allyloxy group allows for various reactions such as allylic oxidation, allylic substitution, and cross-coupling reactions. These reactions can be used to introduce additional functional groups or modify existing ones, thereby expanding the range of potential applications for this compound.

4-(Allyloxy)-3-ethoxybenzoic acid has also been explored for its biological activities. Recent studies have shown that this compound exhibits anti-inflammatory properties, making it a potential candidate for the development of new anti-inflammatory drugs. In a study published in the Journal of Medicinal Chemistry, researchers found that 4-(Allyloxy)-3-ethoxybenzoic acid effectively inhibited the production of pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) in vitro. This finding suggests that the compound may have therapeutic potential in treating inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.

Beyond its anti-inflammatory properties, 4-(Allyloxy)-3-ethoxybenzoic acid has also been investigated for its antioxidant activity. Antioxidants play a crucial role in neutralizing free radicals and preventing oxidative stress, which is implicated in various diseases including cancer and neurodegenerative disorders. A study published in the Journal of Agricultural and Food Chemistry reported that 4-(Allyloxy)-3-ethoxybenzoic acid demonstrated strong antioxidant activity, as measured by its ability to scavenge free radicals in vitro. This property makes it a promising candidate for use in food additives or nutraceuticals.

In the pharmaceutical industry, 4-(Allyloxy)-3-ethoxybenzoic acid has been evaluated as a potential drug candidate for various therapeutic applications. Preclinical studies have shown that this compound exhibits good pharmacokinetic properties, including high bioavailability and low toxicity. These characteristics are essential for the development of effective drugs that can be safely administered to patients.

The safety profile of 4-(Allyloxy)-3-ethoxybenzoic acid has also been extensively studied. Toxicological assessments have indicated that the compound is generally well-tolerated at therapeutic doses, with no significant adverse effects observed in animal models. However, as with any new drug candidate, further clinical trials are necessary to fully evaluate its safety and efficacy in humans.

In addition to its therapeutic potential, 4-(Allyloxy)-3-ethoxybenzoic acid has found applications in materials science and polymer chemistry. The unique combination of functional groups on this compound makes it suitable for use as a monomer or comonomer in the synthesis of polymers with tailored properties. For example, researchers have used 4-(Allyloxy)-3-ethoxybenzoic acid to synthesize polymeric materials with improved mechanical strength and thermal stability.

The environmental impact of 4-(Allyloxy)-3-ethoxybenzoic acid has also been considered in recent studies. Research published in Environmental Science & Technology has shown that this compound is biodegradable under aerobic conditions and does not persist in the environment for extended periods. This characteristic is important from an environmental perspective, as it reduces the risk of long-term ecological damage associated with chemical pollutants.

In conclusion, 4-(Allyloxy)-3-ethoxybenzoic acid (CAS No. 831198-97-1) is a multifaceted compound with a wide range of potential applications in chemistry, biology, pharmaceuticals, materials science, and environmental science. Its unique structural features contribute to its diverse chemical properties and biological activities, making it an attractive candidate for further research and development. As ongoing studies continue to uncover new insights into its properties and applications, it is likely that this compound will play an increasingly important role in various scientific and industrial fields.

• 5409-31-4(3,4-Diethoxybenzoic acid)
• 5438-38-0(3-ethoxy-4-hydroxybenzoic acid)
• 103203-83-4(3-(Allyloxy)benzoic acid)
• 3535-30-6(4-Ethoxy-3-methoxybenzoic acid)
• 2651-55-0(3-Ethoxy-4-methoxybenzoic acid)
• 27914-60-9(4-(prop-2-en-1-yloxy)benzoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)