Cas no 82625-45-4 (4-[2-(morpholin-4-yl)ethoxy]benzaldehyde)

4-[2-(Morpholin-4-yl)ethoxy]benzaldehyde is a versatile synthetic intermediate used in organic and medicinal chemistry. Its structure combines a benzaldehyde core with a morpholine-containing ethoxy linker, making it valuable for constructing complex molecules, particularly in pharmaceutical research. The morpholine moiety enhances solubility and bioavailability, while the aldehyde group provides a reactive site for further functionalization, such as condensation or nucleophilic addition reactions. This compound is particularly useful in the synthesis of biologically active compounds, including potential drug candidates. Its stability under standard conditions and compatibility with diverse reaction conditions make it a practical choice for researchers requiring precise molecular modifications.

4-[2-(morpholin-4-yl)ethoxy]benzaldehyde structure

82625-45-4 structure

Product Name:4-[2-(morpholin-4-yl)ethoxy]benzaldehyde

CAS No:82625-45-4

MF:C₁₃H₁₇NO₃

MW:235.278983831406

MDL:MFCD01822190

CID:720729

PubChem ID:3719902

Update Time:2025-05-24

4-[2-(morpholin-4-yl)ethoxy]benzaldehyde Chemical and Physical Properties

Names and Identifiers

- 4-(2-Morpholinoethoxy)benzaldehyde
- 4-(2-morpholin-4-ylethoxy)benzaldehyde
- 4-(2-MORPHOLIN-4-YL-ETHOXY)-BENZALDEHYDE
- Benzaldehyde,4-[2-(4-morpholinyl)ethoxy]-
- 4-[2-(morpholin-4-yl)ethoxy]benzaldehyde
- FT-0641879
- A840393
- SCHEMBL210577
- 4-[2-(4-morpholinyl)-ethoxy]-benzaldehyde
- CS-0264211
- Z323039274
- 82625-45-4
- J-513335
- PS-5157
- MFCD01822190
- FGLXMUOMJOHGKH-UHFFFAOYSA-N
- AKOS000103464
- 4-(2-morpholinoethoxyl)benzaldehyde
- EN300-92325
- 4-[2-(4-morpholinyl)ethoxy]benzaldehyde
- BB 0217870
- DTXSID20395485
- 4-(2-morpholinoethoxy) benzaldehyde
- BBL015357
- STK347838
- DB-056641
- ALBB-001167
- MDL： MFCD01822190
- Inchi： 1S/C13H17NO3/c15-11-12-1-3-13(4-2-12)17-10-7-14-5-8-16-9-6-14/h1-4,11H,5-10H2
- InChI Key： FGLXMUOMJOHGKH-UHFFFAOYSA-N
- SMILES： O1CCN(CCOC2C=CC(C=O)=CC=2)CC1

Computed Properties

Exact Mass: 235.12100
Monoisotopic Mass: 235.121
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Heavy Atom Count: 17
Rotatable Bond Count: 5
Complexity: 221
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 38.8A^2
XLogP3: 1

Experimental Properties

Density: 1.141
Boiling Point: 164/0.3mm
Flash Point: 192.6°C
Refractive Index: 1.552
PSA: 38.77000
LogP: 1.14800

4-[2-(morpholin-4-yl)ethoxy]benzaldehyde Security Information

Hazard Statement： Corrosive
Hazardous Material Identification：
HazardClass：IRRITANT

4-[2-(morpholin-4-yl)ethoxy]benzaldehyde Customs Data

HS CODE：2934999090
Customs Data：

China Customs Code:
2934999090

Overview:

2934999090. Other heterocyclic compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

Declaration elements:

Product Name, component content, use to

Summary:

2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-[2-(morpholin-4-yl)ethoxy]benzaldehyde Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
Fluorochem	031324-1g	4-(2-Morpholin-4-yl-ethoxy)-benzaldehyde	82625-45-4	90%	1g	￡88.00	2022-03-01
Fluorochem	031324-5g	4-(2-Morpholin-4-yl-ethoxy)-benzaldehyde	82625-45-4	90%	5g	￡257.00	2022-03-01
Alichem	A449036375-5g	4-(2-Morpholinoethoxy)benzaldehyde	82625-45-4	95%	5g	$478.29	2023-09-01
TRC	B497383-50mg	4-(2-Morpholin-4-ylethoxy)benzaldehyde	82625-45-4		50mg	$ 50.00	2022-06-07
TRC	B497383-100mg	4-(2-Morpholin-4-ylethoxy)benzaldehyde	82625-45-4		100mg	$ 65.00	2022-06-07
TRC	B497383-500mg	4-(2-Morpholin-4-ylethoxy)benzaldehyde	82625-45-4		500mg	$ 160.00	2022-06-07
Chemenu	CM113328-5g	4-(2-morpholin-4-ylethoxy)benzaldehyde	82625-45-4	95%	5g	$453	2021-08-06
abcr	AB223533-500 mg	4-(2-Morpholinoethoxy)benzaldehyde; 95%	82625-45-4		500MG	€151.00	2023-02-22
abcr	AB223533-1 g	4-(2-Morpholinoethoxy)benzaldehyde; 95%	82625-45-4		1 g	€172.20	2023-07-20
abcr	AB223533-5 g	4-(2-Morpholinoethoxy)benzaldehyde; 95%	82625-45-4		5 g	€389.30	2023-07-20

4-[2-(morpholin-4-yl)ethoxy]benzaldehyde Suppliers

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:82625-45-4)4-[2-(morpholin-4-yl)ethoxy]benzaldehyde

Order Number:A840393

Stock Status:in Stock

Quantity:5g

Purity:99%

Pricing Information Last Updated:Friday, 30 August 2024 06:49

Price ($):523.0

Email:[email protected]

Product Official Link

4-[2-(morpholin-4-yl)ethoxy]benzaldehyde Related Literature

1. Fast-pulsing NMR techniques for the detection of weak interactions: successful natural abundance probe of hydrogen bonds in peptides?

Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
2. Exceptionally high temperature spin crossover in amide-functionalised 2,6-bis(pyrazol-1-yl)pyridine iron(ii) complex revealed by variable temperature Raman spectroscopy and single crystal X-ray diffraction?

Max Attwood,Hiroki Akutsu,Lee Martin,Toby J. Blundell,Pierre Le Maguere,Scott S. Turner Dalton Trans., 2021,50, 11843-11851
3. Fe3O4 nanoparticle chains with N-doped carbon coating: magnetotactic bacteria assisted synthesis and high-rate lithium storage?

Dan Yang,Yanping Zhou,Xianhong Rui,Jixin Zhu,Ziyang Lu,Eileen Fong,Qingyu Yan RSC Adv., 2013,3, 14960-14962
4. Fate of Sb(v) and Sb(iii) species along a gradient of pH and oxygen concentration in the Carnoulès mine waters (Southern France)

Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
5. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?

Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139

Additional information on 4-[2-(morpholin-4-yl)ethoxy]benzaldehyde

Comprehensive Overview of 4-[2-(morpholin-4-yl)ethoxy]benzaldehyde (CAS No. 82625-45-4): Properties, Applications, and Industry Insights

4-[2-(morpholin-4-yl)ethoxy]benzaldehyde (CAS No. 82625-45-4) is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research due to its unique structural features. This compound, characterized by a benzaldehyde core linked to a morpholine moiety via an ethoxy spacer, serves as a versatile intermediate in synthetic chemistry. Its molecular formula, C₁₃H₁₇NO₃, and molecular weight of 235.28 g/mol make it a valuable building block for designing bioactive molecules. Researchers frequently explore its role in drug discovery, particularly for modulating kinase inhibitors and GPCR-targeted therapies, aligning with current trends in precision medicine.

The compound’s physicochemical properties include a pale-yellow to off-white crystalline appearance, moderate solubility in polar organic solvents like DMSO and methanol, and stability under controlled conditions. These traits facilitate its use in high-throughput screening (HTS) and combinatorial chemistry. Recent studies highlight its utility in synthesizing heterocyclic derivatives, which are pivotal in developing anticancer agents and neuroprotective compounds. Such applications resonate with the growing demand for targeted therapies in oncology and neurodegenerative diseases, topics frequently searched in academic and industrial databases.

From an industrial perspective, 4-[2-(morpholin-4-yl)ethoxy]benzaldehyde is synthesized via nucleophilic substitution reactions, often involving 4-hydroxybenzaldehyde and 2-chloroethylmorpholine. Optimized protocols emphasize green chemistry principles, such as reduced solvent waste and catalytic efficiency, addressing the pharmaceutical sector’s focus on sustainable synthesis. Analytical techniques like HPLC, NMR, and mass spectrometry ensure high purity (>98%), critical for regulatory compliance in API manufacturing.

Emerging trends in AI-driven drug design have further amplified interest in this compound. Computational models leverage its molecular scaffold to predict binding affinities for protein targets, a topic dominating PubMed and SciFinder queries. Additionally, its potential in photodynamic therapy (PDT) and fluorescent probes aligns with advancements in theranostics, a hot topic in biomedical research. These applications underscore its relevance in translational medicine, bridging lab-scale discoveries to clinical solutions.

Quality control and supply chain transparency are critical for CAS No. 82625-45-4, as stakeholders prioritize GMP-certified suppliers and batch-to-batch consistency. Regulatory frameworks like REACH and ICH guidelines govern its handling, ensuring safety in industrial workflows. Furthermore, patents involving this compound often cite its use in bioconjugation and prodrug development, reflecting innovation in drug delivery systems.

In summary, 4-[2-(morpholin-4-yl)ethoxy]benzaldehyde exemplifies the intersection of structural elegance and functional versatility. Its applications span medicinal chemistry, material science, and diagnostic imaging, making it a compound of enduring scientific and commercial value. As research continues to unravel its potential, this molecule remains a cornerstone in the quest for next-generation therapeutics and smart materials.

82625-45-4 (4-[2-(morpholin-4-yl)ethoxy]benzaldehyde) Related Products

Recommended suppliers