Cas no 82375-29-9 (Humantenine)
Humantenine is a naturally occurring alkaloid derived from the plant Gelsemium elegans, known for its complex indole structure. It exhibits notable biological activity, particularly as a negative allosteric modulator of glycine receptors, making it a compound of interest in neuropharmacological research. Humantenine's selective binding properties contribute to its potential in studying receptor modulation and synaptic transmission. Its high purity and well-characterized structure ensure reliability for experimental applications. Researchers value Humantenine for its utility in probing neurological pathways and its role as a reference standard in analytical chemistry. Proper handling is advised due to its bioactive nature.
Humantenine structure
Product Name:Humantenine
CAS No:82375-29-9
MF:C21H26N2O3
MW:354.442745685577
CID:724044
PubChem ID:44593672
Update Time:2025-10-12
Humantenine Chemical and Physical Properties
Names and Identifiers
-
- Humantenine
- [ "" ]
- (3S,3′Z,4′R,4′aS,7′R,9′aS)-3′-Ethylidene-1′,2′,3′,4′,4′a,5′,9′,9′a-octahydro-1-methoxy-1′-methylspiro[3H-indole-3,8′(7′H)-[4,7]methanooxepino[4,3-b]pyridin]-2(1H)-one (ACI)
- Humantenine (ZCI)
- [4′R-(3′Z,4′α,4′aβ,7′α,8′α,9′aβ)]-3′-Ethylidene-1′,2′,3′,4′,4′a,5′,9′,9′a-octahydro-1-methoxy-1′-methylspiro[3H-indole-3,8′(7′H)-[4,7]methanooxepino[4,3-b]pyridin]-2(1H)-one
- Spiro[3H-indole-3,8′(7′H)-[4,7]methanooxepino[4,3-b]pyridin]-2(1H)-one, 3′-ethylidene-1′,2′,3′,4′,4′a,5′,9′,9′a-octahydro-1-methoxy-1′-methyl-, [4′R-(3′Z,4′α,4′aβ,7′α,8′α,9′aβ)]-
- (19Z)-Rhazine
- 19(Z)-Akuammidine
- CHEMBL523399
- AKOS040760452
- DTXSID601318183
- 82375-29-9
- 1ST161134
- (1R,2S,4S,7Z,8R,9S)-7-ethylidene-1'-methoxy-5-methylspiro[11-oxa-5-azatricyclo[6.3.1.04,9]dodecane-2,3'-indole]-2'-one
- HY-N4031
- CS-0024484
- Gelsenidine
- (1R,2S,4S,7Z,8R,9S)-7-ethylidene-1'-methoxy-5-methylspiro(11-oxa-5-azatricyclo(6.3.1.04,9)dodecane-2,3'-indole)-2'-one
- DA-64301
-
- Inchi: 1S/C21H26N2O3/c1-4-13-11-22(2)18-10-21(19-9-14(13)15(18)12-26-19)16-7-5-6-8-17(16)23(25-3)20(21)24/h4-8,14-15,18-19H,9-12H2,1-3H3/b13-4+/t14-,15-,18-,19+,21-/m0/s1
- InChI Key: SJKRPUOXUNOPOP-YDAOCWKESA-N
- SMILES: O=C1N(OC)C2C=CC=CC=2[C@@]21C[C@@H]1N(C/C(/[C@H]3[C@@H]1CO[C@@H]2C3)=C\C)C
Computed Properties
- Exact Mass: 354.19400
- Monoisotopic Mass: 354.19434270 g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 26
- Rotatable Bond Count: 1
- Complexity: 635
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 5
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 1
- Undefined Bond Stereocenter Count: 0
- Molecular Weight: 354.4
- XLogP3: 1.7
- Topological Polar Surface Area: 42?2
Experimental Properties
- Color/Form: Powder
- PSA: 42.01000
- LogP: 2.52060
Humantenine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd | BP4258-5mg |
Humantenine |
82375-29-9 | 98% | 5mg |
$350 | 2023-09-20 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | H88650-5mg |
Humantenine |
82375-29-9 | ,HPLC≥95.0% | 5mg |
¥6400.0 | 2023-09-07 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TN1747-1 mg |
Humantenine |
82375-29-9 | 1mg |
¥3233.00 | 2022-04-26 | ||
| A2B Chem LLC | AH54353-5mg |
humantenine |
82375-29-9 | 98.0% | 5mg |
$802.00 | 2024-04-19 | |
| Aaron | AR00G6WT-5mg |
Humantenine |
82375-29-9 | 98% | 5mg |
$916.00 | 2025-02-13 | |
| TargetMol Chemicals | TN1747-1 ml * 10 mm |
Humantenine |
82375-29-9 | 1 ml * 10 mm |
¥ 4610 | 2024-07-20 | ||
| A2B Chem LLC | AH54353-1mg |
humantenine |
82375-29-9 | >98% | 1mg |
$599.00 | 2024-04-19 | |
| TargetMol Chemicals | TN1747-5 mg |
Humantenine |
82375-29-9 | 98% | 5mg |
¥ 4,510 | 2023-07-11 | |
| TargetMol Chemicals | TN1747-1 mL * 10 mM (in DMSO) |
Humantenine |
82375-29-9 | 98% | 1 mL * 10 mM (in DMSO) |
¥ 4610 | 2023-09-15 | |
| TargetMol Chemicals | TN1747-5mg |
Humantenine |
82375-29-9 | 5mg |
¥ 4510 | 2024-07-20 |
Humantenine Related Literature
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Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
-
Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
-
Abdelaziz Houmam,Emad M. Hamed Chem. Commun., 2012,48, 11328-11330
-
Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
-
Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
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