Cas no 82039-84-7 (5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid)

5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid is a benzofuran derivative with a hydroxyl group at the 5-position and a carboxylic acid moiety at the 3-position. This compound serves as a versatile intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its structural features, including the electron-rich benzofuran core and functional groups, make it suitable for further derivatization, such as esterification or amidation. The presence of both hydroxyl and carboxylic acid groups enhances its reactivity, enabling applications in heterocyclic chemistry and ligand design. High purity grades are available for research and industrial use, ensuring consistent performance in synthetic workflows.
5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid structure
82039-84-7 structure
Product Name:5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid
CAS No:82039-84-7
MF:C10H8O4
MW:192.168123245239
CID:3073941
PubChem ID:668281
Update Time:2025-05-19

5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid Chemical and Physical Properties

Names and Identifiers

    • 5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid
    • CCG-108351
    • 5-Hydroxy-2-methylbenzofuran-3-carboxylic acid
    • F76874
    • Z275255660
    • Oprea1_684004
    • STK523123
    • 5-hydroxy-2-methyl-1-benzofuran-3-carboxylic acid
    • IDI1_020754
    • ChemDiv3_001788
    • UNM000011034301
    • MFCD00040261
    • HMS1478B06
    • SCHEMBL24470616
    • 5-Hydroxy-2-methyl-1-benzofuran-3-carboxylic acid, AldrichCPR
    • AKOS000164194
    • DB-087995
    • 5-Hydroxy-2-methylbenzofuran-3-carboxylicacid
    • AF-407/31882016
    • SR-01000455308
    • SR-01000455308-1
    • 82039-84-7
    • 973-586-7
    • HDA03984
    • Inchi: 1S/C10H8O4/c1-5-9(10(12)13)7-4-6(11)2-3-8(7)14-5/h2-4,11H,1H3,(H,12,13)
    • InChI Key: PMQFCQKIRJLFAS-UHFFFAOYSA-N
    • SMILES: O1C(C)=C(C(=O)O)C2C=C(C=CC1=2)O

Computed Properties

  • Exact Mass: 192.04225873g/mol
  • Monoisotopic Mass: 192.04225873g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 1
  • Complexity: 240
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.9
  • Topological Polar Surface Area: 70.7?2

5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid Security Information

  • Hazardous Material Identification: Xi
  • HazardClass:IRRITANT

5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid Pricemore >>

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Additional information on 5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid

5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid (CAS No. 82039-84-7): Properties, Applications, and Market Insights

5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid (CAS No. 82039-84-7) is a specialized organic compound belonging to the benzofuran family. This compound has garnered significant attention in pharmaceutical and chemical research due to its unique structural features and potential biological activities. With the increasing demand for novel bioactive molecules, 5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid has become a subject of interest for researchers exploring new therapeutic agents and synthetic intermediates.

The molecular structure of 5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid combines a benzofuran core with a carboxylic acid functional group at the 3-position and a hydroxyl group at the 5-position. This arrangement contributes to its distinct chemical properties, including moderate solubility in polar organic solvents and potential for hydrogen bonding. The presence of both acidic and phenolic groups makes this compound particularly interesting for applications in medicinal chemistry and material science.

Recent studies have focused on the potential pharmaceutical applications of 5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid derivatives. Researchers are investigating its role as a building block for more complex molecules with potential anti-inflammatory or antioxidant properties. The compound's structural similarity to certain natural products has sparked interest in its possible biological activities, making it a valuable target for drug discovery programs.

In the field of organic synthesis, 5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid serves as a versatile intermediate. Its reactive functional groups allow for various chemical transformations, enabling the creation of diverse molecular architectures. Synthetic chemists value this compound for its ability to participate in coupling reactions, esterifications, and other key transformations that are fundamental to modern organic synthesis.

The analytical characterization of 5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid typically involves techniques such as HPLC, NMR spectroscopy, and mass spectrometry. These methods confirm the compound's purity and structural integrity, which are crucial for research and industrial applications. Recent advancements in analytical technology have improved the detection and quantification of this compound in complex matrices.

Market trends indicate growing interest in benzofuran-based compounds like 5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid. The global market for specialty chemicals continues to expand, with particular growth in the pharmaceutical intermediates sector. Manufacturers and suppliers are responding to increased demand by optimizing production processes and ensuring consistent quality of this valuable chemical building block.

Environmental and safety considerations for handling 5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid follow standard laboratory protocols for organic compounds. While not classified as hazardous under normal conditions, proper storage in cool, dry conditions and the use of appropriate personal protective equipment are recommended when working with this chemical.

Future research directions for 5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid may explore its potential in green chemistry applications, biodegradable materials, or as a precursor for fluorescent compounds. The compound's unique structure offers numerous possibilities for innovation in various chemical disciplines, making it an exciting area for continued investigation.

For researchers and industry professionals seeking high-quality 5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid, it's essential to source the compound from reputable suppliers who can provide comprehensive analytical data and documentation. The compound's purity and consistency are critical factors that can significantly impact research outcomes and process development.

In conclusion, 5-Hydroxy-2-methyl-benzofuran-3-carboxylic acid (CAS No. 82039-84-7) represents an important member of the benzofuran chemical family with diverse potential applications. Its unique structural features and reactivity profile continue to make it valuable for pharmaceutical research, organic synthesis, and material science. As scientific understanding of this compound grows, so too does its potential to contribute to advancements in multiple chemical disciplines.

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