Cas no 820-11-1 (Propanoic acid,2-hydroxy-3-(phosphonooxy)-)

Propanoic acid, 2-hydroxy-3-(phosphonooxy)-, is a phosphorylated hydroxy acid derivative with significant utility in biochemical and industrial applications. Its structure, featuring both carboxyl and phosphonooxy functional groups, enables chelating properties and participation in phosphorylation reactions. This compound is particularly valuable in enzymatic studies and metal ion coordination due to its ability to mimic natural phosphorylated metabolites. Its stability under physiological conditions makes it suitable for research in metabolic pathways and signal transduction. Additionally, the presence of multiple reactive sites allows for versatile chemical modifications, facilitating its use in synthesizing specialized intermediates for pharmaceuticals and agrochemicals.
Propanoic acid,2-hydroxy-3-(phosphonooxy)- structure
820-11-1 structure
Product Name:Propanoic acid,2-hydroxy-3-(phosphonooxy)-
CAS No:820-11-1
MF:C3H7O7P
MW:186.057242631912
CID:721311
PubChem ID:724
Update Time:2025-10-28

Propanoic acid,2-hydroxy-3-(phosphonooxy)- Chemical and Physical Properties

Names and Identifiers

    • Propanoic acid,2-hydroxy-3-(phosphonooxy)-
    • (2R)-2-hydroxy-3-phosphonatooxypropanoate
    • 3-phosphoglyceric acid
    • 3-phosphoglycerate
    • DTXSID601002368
    • 2-oxidanyl-3-phosphonooxy-propanoic acid
    • glycerate 3-phosphate
    • CS-0062388
    • 3-(dihydrogen phosphate)Glycerate
    • DL-Glycerate 3-phosphate
    • 820-11-1
    • Propanoic acid, 2-hydroxy-3-(phosphonooxy)-
    • 3-P-glycerate
    • C00597
    • 3-(dihydrogen phosphate)Glyceric acid
    • AKOS040744141
    • A841756
    • 76C0138A-0EA9-4A51-B2C9-BAEC6DE64355
    • 3-Glycerophosphorate
    • BDBM50469695
    • Glyceric acid-3-phosphate
    • Q32904835
    • glycerate 3-phosphates
    • 2-hydroxy-3-(phosphonooxy)propanoic acid
    • Glyceric acid 3-phosphate
    • CHEBI:17050
    • 3-PGA
    • 3-phospho-glyceric acid
    • SCHEMBL27482
    • glycerate-3-P
    • 3-pg
    • CHEMBL87788
    • 3-phospho-glycerate
    • D-(-)-3-Phosphoglyceric acid
    • NS00014807
    • HY-113491
    • g3p
    • 2-hydroxy-3-phosphonooxypropanoic acid
    • 3-P-D-glycerate
    • 3-Glycerophosphoric acid
    • 3-phospho-(R)-glycerate
    • CHEBI:17794
    • (2R)-2-hydroxy-3-(phosphonooxy)propanoic acid
    • OSJPPGNTCRNQQC-UWTATZPHSA-N
    • Q223118
    • D-Glycerate 3-phosphate
    • 3PG
    • CHEMBL1160563
    • NS00069414
    • DB04510
    • 3-phospho-D-glycerate
    • bmse000007
    • 1iih
    • HG3
    • 3443-58-1
    • BDBM50216218
    • 2-D-Hydroxy-3-phosphonooxy-propanoic acid
    • PD059234
    • SCHEMBL2497743
    • 3-phospho-D-glyceric acid
    • C00197
    • DTXSID40862427
    • 3-phosphoglycerate(3-)
    • 3-phosphonato-D-glycerate trianion
    • D-3-Phosphoglyceric acid
    • (2R)-2-Hydroxy-3-(phosphonatooxy)propanoate
    • 3-phosphonato-D-glycerate(3-)
    • (2R)-3-phosphoglycerate
    • 3-phosphonato-D-glycerate
    • Inchi: 1S/C3H7O7P/c4-2(3(5)6)1-10-11(7,8)9/h2,4H,1H2,(H,5,6)(H2,7,8,9)
    • InChI Key: OSJPPGNTCRNQQC-UHFFFAOYSA-N
    • SMILES: P(=O)(O)(O)OCC(C(=O)O)O

Computed Properties

  • Exact Mass: 185.99293956g/mol
  • Monoisotopic Mass: 185.99293956g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 4
  • Hydrogen Bond Acceptor Count: 7
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 4
  • Complexity: 182
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -2.6
  • Topological Polar Surface Area: 124?2

Propanoic acid,2-hydroxy-3-(phosphonooxy)- Pricemore >>

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Additional information on Propanoic acid,2-hydroxy-3-(phosphonooxy)-

Propanoic Acid, 2-Hydroxy-3-(Phosphonooxy)- (CAS No. 820-11-1): A Comprehensive Overview

Propanoic acid, 2-hydroxy-3-(phosphonooxy)-, also known by its CAS registry number 820-11-1, is a chemical compound that has garnered significant attention in recent years due to its unique properties and diverse applications. This compound belongs to the class of organic phosphonic acids, which are widely studied for their role in various biological and industrial processes. The molecule consists of a propanoic acid backbone with a hydroxyl group at the second carbon and a phosphonooxy group at the third carbon, making it a structurally interesting compound with potential for further functionalization.

The synthesis of propanoic acid, 2-hydroxy-3-(phosphonooxy)- typically involves the reaction of appropriate phosphonic acid derivatives with alcohols or other nucleophiles under specific conditions. Recent advancements in catalytic methods have enabled more efficient and selective syntheses, reducing the environmental footprint of its production. Researchers have also explored the use of biocatalysts, such as enzymes, to facilitate the formation of this compound, aligning with the growing trend toward sustainable chemistry.

In terms of physical properties, propanoic acid, 2-hydroxy-3-(phosphonooxy)- is known for its high solubility in polar solvents due to the presence of both hydrophilic hydroxyl and phosphonooxy groups. Its melting point and boiling point are consistent with those of similar organic acids, making it suitable for use in various thermal processes. The compound's stability under different pH conditions has also been extensively studied, revealing its resilience in both acidic and neutral environments.

The biological activity of propanoic acid, 2-hydroxy-3-(phosphonooxy)- has been a focal point in recent research. Studies have demonstrated its potential as an inhibitor of certain enzymes, particularly those involved in metabolic pathways. For instance, investigations into its interaction with serine proteases have shown promising results, suggesting its application as a therapeutic agent in treating conditions associated with excessive enzymatic activity. Additionally, the compound has been explored as a component in drug delivery systems due to its ability to enhance bioavailability and reduce side effects.

In the industrial sector, propanoic acid, 2-hydroxy-3-(phosphonooxy)- finds utility in the formulation of detergents and cleaning agents. Its phosphonooxy group contributes to its chelating properties, allowing it to effectively sequester metal ions and prevent their interference in cleaning processes. This attribute has made it a valuable additive in laundry detergents and hard surface cleaners, enhancing their performance under various water hardness conditions.

Recent breakthroughs in materials science have also highlighted the potential of propanoic acid, 2-hydroxy-3-(phosphonooxy)- as a building block for advanced materials. Its ability to form stable complexes with metal ions has led to its use in the synthesis of metal-organic frameworks (MOFs) and coordination polymers. These materials exhibit exceptional porosity and selectivity, making them ideal candidates for gas storage and separation applications.

The environmental impact of propanoic acid, 2-hydroxy-3-(phosphonooxy)- has been another area of active research. Studies have assessed its biodegradability under aerobic and anaerobic conditions, revealing that it undergoes rapid degradation by microbial action without leaving harmful residues. This characteristic is particularly advantageous for its use in eco-friendly products and processes.

In conclusion, propanoic acid, 2-hydroxy-3-(phosphonooxy)- (CAS No. 820-11-1) is a versatile compound with applications spanning pharmaceuticals, detergents, and materials science. Its unique chemical structure and favorable properties continue to drive innovation across multiple disciplines. As research progresses, new insights into its functionality are expected to unlock even greater potential for this intriguing molecule.

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