Cas no 81183-56-4 (N-(2,5-Difluoro-phenyl)-formamide)

N-(2,5-Difluoro-phenyl)-formamide is a fluorinated aromatic formamide derivative with potential applications in pharmaceutical and agrochemical research. Its structure, featuring difluoro substitution on the phenyl ring, enhances electronic properties and metabolic stability, making it a valuable intermediate in the synthesis of bioactive compounds. The formamide group provides a reactive site for further functionalization, enabling diverse derivatization pathways. This compound exhibits good solubility in common organic solvents, facilitating its use in synthetic workflows. Its well-defined molecular architecture and stability under standard conditions make it a reliable building block for developing fluorinated analogs in medicinal chemistry and material science applications.

N-(2,5-Difluoro-phenyl)-formamide structure

81183-56-4 structure

Product Name:N-(2,5-Difluoro-phenyl)-formamide

CAS No:81183-56-4

MF:C₇H₅F₂NO

MW:157.117508649826

CID:704367

PubChem ID:12803461

Update Time:2025-06-07

N-(2,5-Difluoro-phenyl)-formamide Chemical and Physical Properties

Names and Identifiers

- Formamide, N-(2,5-difluorophenyl)-
- N-(2,5-difluorophenyl)formamide
- N-(2,5-Difluoro-phenyl)-forMaMide
- G10277
- FOMMCVBZFYSEFW-UHFFFAOYSA-N
- AKOS014324242
- 81183-56-4
- SCHEMBL1759061
- DTXSID00510250
- N-(2,5-Difluoro-phenyl)-formamide
- Inchi： 1S/C7H5F2NO/c8-5-1-2-6(9)7(3-5)10-4-11/h1-4H,(H,10,11)
- InChI Key： FOMMCVBZFYSEFW-UHFFFAOYSA-N
- SMILES： FC1C=CC(=CC=1NC=O)F

Computed Properties

Exact Mass: 157.03392011g/mol
Monoisotopic Mass: 157.03392011g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Heavy Atom Count: 11
Rotatable Bond Count: 2
Complexity: 142
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 1.3
Topological Polar Surface Area: 29.1?2

Experimental Properties

Density: 1.4±0.0 g/cm3
Boiling Point: 281.4±0.0 °C at 760 mmHg
Flash Point: 124.0±0.0 °C
Vapor Pressure: 0.0±0.0 mmHg at 25°C

N-(2,5-Difluoro-phenyl)-formamide Security Information

Signal Word：warning
Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
Warning Statement： P264+P280+P305+P351+P338+P337+P313
Safety Instruction： H303+H313+H333
Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)

N-(2,5-Difluoro-phenyl)-formamide Pricemore >>

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TRC	D456273-500mg	N-(2,5-Difluoro-phenyl)-formamide	81183-56-4		500mg	$ 295.00	2022-06-05
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