• 1. Dissociation of large gaseous serine clusters produces abundant protonated serine octamer
  Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625
• 2. Emulsion technologies for multicellular tumour spheroid radiation assays?
  Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
• 3. Emulsion soft templating of carbide-derived carbon nanospheres with controllable porosity for capacitive electrochemical energy storage?
  M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
• 4. Dissociation of aryl sulfonyl phthalimide radical anions: relevance to the biological activity of arylsulfonyl amides?
  Abdelaziz Houmam,Emad M. Hamed Chem. Commun., 2012,48, 11328-11330
• 5. Excitation energies from ground-state density-functionals by means of generator coordinates
  A. B. F. da Silva,K. Capelle Phys. Chem. Chem. Phys., 2009,11, 4564-4569

Pyridine,4-(4-methyl-1-piperidinyl)- (CAS No. 80965-30-6): A Comprehensive Overview

Pyridine,4-(4-methyl-1-piperidinyl)-, identified by its CAS No. 80965-30-6, is a specialized organic compound that has garnered significant attention in the field of medicinal chemistry and material science. This compound, often referred to as 4-(4-Methylpiperidin-1-yl)pyridine, is a derivative of pyridine, a heterocyclic aromatic compound known for its versatile applications. The integration of a 4-methylpiperidinyl group enhances its chemical properties, making it a valuable intermediate in various synthetic processes.

The molecular structure of Pyridine,4-(4-methyl-1-piperidinyl)- features a pyridine ring substituted at the 4-position with a 4-methylpiperidinyl moiety. This structural configuration imparts unique electronic and steric properties, which are crucial for its reactivity and interaction with other molecules. Researchers have explored its potential in the development of pharmaceutical intermediates, ligands for catalysis, and functional materials. Its ability to act as a chelating agent or a building block in organic synthesis has made it a subject of interest in academic and industrial research.

One of the key applications of Pyridine,4-(4-methyl-1-piperidinyl)- lies in its role as a precursor for drug discovery. The compound's structural motif is often found in molecules with biological activity, particularly those targeting central nervous system (CNS) disorders. Recent studies have highlighted its potential in the design of neuromodulators and receptor antagonists, aligning with the growing demand for novel therapeutics in mental health and neurodegenerative diseases. This connection to healthcare innovation has driven its popularity in scientific literature and patent filings.

In addition to its pharmaceutical relevance, Pyridine,4-(4-methyl-1-piperidinyl)- has found utility in material science. Its ability to coordinate with metal ions makes it a candidate for designing metal-organic frameworks (MOFs) and catalysts. The compound's thermal stability and solubility profile further enhance its suitability for applications in advanced coatings and electronic materials. As industries increasingly focus on sustainable technologies, the demand for such specialized intermediates is expected to rise.

The synthesis of Pyridine,4-(4-methyl-1-piperidinyl)- typically involves nucleophilic substitution reactions or cross-coupling methodologies. Researchers have optimized these processes to achieve high yields and purity, ensuring its availability for large-scale applications. Analytical techniques such as NMR spectroscopy and mass spectrometry are commonly employed to characterize the compound, confirming its structural integrity and purity. These advancements in synthetic chemistry have contributed to its widespread adoption in research and development.

From a market perspective, the demand for Pyridine,4-(4-methyl-1-piperidinyl)- is influenced by trends in pharmaceutical R&D and green chemistry. Companies specializing in fine chemicals and custom synthesis are actively investing in the production of this compound to meet the needs of academic institutions and industrial laboratories. Its compatibility with high-throughput screening and combinatorial chemistry further underscores its value in modern drug discovery pipelines.

Environmental and safety considerations are paramount when handling Pyridine,4-(4-methyl-1-piperidinyl)-. While the compound is not classified as hazardous under standard regulations, proper laboratory practices and personal protective equipment (PPE) are recommended to ensure safe usage. Regulatory compliance, including adherence to REACH and GMP guidelines, is essential for its commercial distribution and application in sensitive industries.

Looking ahead, the future of Pyridine,4-(4-methyl-1-piperidinyl)- appears promising, with ongoing research exploring its potential in bioconjugation, nanotechnology, and smart materials. As the scientific community continues to uncover new applications, this compound is poised to play a pivotal role in advancing cutting-edge technologies and therapeutic innovations. Its versatility and adaptability make it a cornerstone in the ever-evolving landscape of chemical sciences.

• 69008-71-5(4-(N,N-Dibutylamino)pyridine)
• 140177-00-0(4-Pyridinamine, N-decyl-N-methyl-)
• 352445-70-6(3-(Pyridin-4-yl)-3,9-diazaspiro5.5undecane 2HCl)
• 2456-81-7(4-(pyrrolidin-1-yl)pyridine)
• 2767-90-0((1-Pyridin-4-yl)piperidine)
• 544696-22-2(4-Pyridinamine, N-methyl-N-(4-piperidinylmethyl)-, hydrochloride)
• 130658-67-2((3,4,5,6-Tetrahydro-2H-1,4bipyridinyl-4-yl)-methanol)
• 110105-91-4(4-Pyridinamine, N-(4-piperidinylmethyl)-)
• 229647-10-3(Piperazine, 1-[[1-(4-pyridinyl)-4-piperidinyl]methyl]-)
• 69008-70-4(N,N-Dipropylpyridin-4-Amine)