• 1. Exchanged ligands on the surface of a giant cluster: [(MoO3)176(H2O)63(CH3OH)17Hn](32 – n)–
  Chem. Commun., 1998, 1501-1502
• 2. Excellent electrochemical performance of LiFe0.4Mn0.6PO4 microspheres produced using a double carbon coating process?
  Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
• 3. Fast-Track to Research Data Management in Experimental Material Science-Setting the Ground for Research Group Level Materials Digitalization.
  LarsBanko,AlfredLudwig
• 4. Establishing the accuracy of position-specific carbon isotope analysis of propane by GC-pyrolysis-GC-IRMS
  ChangjieLiu,PengLiu,XiaofengWang,XiaoqiangLi,JuskeHorita
• 5. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?
  Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139

Professional Introduction to 3-Hydroxy-4-methoxy-5-nitrobenzaldehyde (CAS No. 80547-69-9)

3-Hydroxy-4-methoxy-5-nitrobenzaldehyde, a compound with the chemical formula C?H?NO?, is a significant intermediate in the field of organic synthesis and pharmaceutical research. This compound, identified by its unique CAS number 80547-69-9, has garnered attention due to its versatile applications in the development of various bioactive molecules. The structural features of this aldehyde derivative, characterized by the presence of hydroxyl, methoxy, and nitro functional groups, make it a valuable precursor in synthetic chemistry.

The 3-Hydroxy-4-methoxy-5-nitrobenzaldehyde molecule exhibits a distinct aromatic system that allows for diverse chemical transformations. These transformations are particularly useful in the synthesis of complex molecules, including pharmaceuticals and agrochemicals. The nitro group, in particular, provides a reactive site for reduction or conversion into other functional groups, while the hydroxyl and methoxy groups contribute to the compound's solubility and reactivity in various solvents.

In recent years, there has been a growing interest in exploring the potential of this compound in medicinal chemistry. Researchers have leveraged its structural framework to develop novel compounds with therapeutic properties. For instance, studies have demonstrated its utility in synthesizing analogs of natural products with anti-inflammatory and anticancer activities. The ability to modify the aromatic core of 3-Hydroxy-4-methoxy-5-nitrobenzaldehyde allows chemists to fine-tune the biological activity of derived compounds, making it an attractive scaffold for drug discovery.

The role of this compound in synthetic organic chemistry is also noteworthy. It serves as a key intermediate in the preparation of more complex molecules through various reactions such as condensation, oxidation, and reduction. These reactions are fundamental to the construction of intricate organic structures, which are often required in pharmaceutical applications. The versatility of 3-Hydroxy-4-methoxy-5-nitrobenzaldehyde makes it a staple in many synthetic routes.

Advances in computational chemistry have further enhanced the understanding and application of this compound. Molecular modeling studies have provided insights into its reactivity and interaction with biological targets. These studies are crucial for designing molecules with improved efficacy and reduced side effects. By integrating experimental data with computational predictions, researchers can optimize synthetic strategies and predict the behavior of 3-Hydroxy-4-methoxy-5-nitrobenzaldehyde-based compounds more accurately.

The pharmaceutical industry has also benefited from the use of 3-Hydroxy-4-methoxy-5-nitrobenzaldehyde in drug development. Its structural motifs are found in several marketed drugs, highlighting its importance as a building block. The compound's ability to undergo multiple chemical modifications allows for the creation of libraries of derivatives with varying biological profiles. This flexibility is essential for identifying lead compounds that can be further optimized through structure-activity relationship (SAR) studies.

In conclusion, 3-Hydroxy-4-methoxy-5-nitrobenzaldehyde (CAS No. 80547-69-9) is a multifaceted compound with significant applications in organic synthesis and pharmaceutical research. Its unique structural features and reactivity make it a valuable tool for developing new bioactive molecules. As research continues to evolve, the potential uses of this compound are likely to expand, further solidifying its role as an important intermediate in chemical biology and drug discovery.

• 31680-08-7(4-Methoxy-3-nitrobenzaldehyde)
• 54291-82-6(Benzaldehyde, 4-(5-formyl-2-hydroxyphenoxy)-3-nitro-)
• 54291-66-6(Benzaldehyde,4-(5-formyl-2-hydroxy-3-methoxyphenoxy)-3-methoxy-5-nitro-)
• 178686-24-3(3-Ethoxy-4-hydroxy-5-nitrobenzaldehyde)
• 6635-20-7(5-Nitrovanillin)
• 22027-96-9(3,4-Dimethoxy-5-nitrobenzaldehyde)
• 80547-65-5(Benzoic acid, 3-hydroxy-4-methoxy-5-nitro-)
• 15962-63-7(4-(4-Methoxyphenoxy)-3-nitrobenzaldehyde)
• 54291-78-0(Benzaldehyde, 4-(2-methoxyphenoxy)-3-nitro-)
• 54291-67-7(Benzaldehyde, 4-(5-formyl-2-hydroxyphenoxy)-3-methoxy-5-nitro-)