Cas no 80023-25-2 (3-chloro-2-cyanobenzene-1-sulfonyl chloride)

3-Chloro-2-cyanobenzene-1-sulfonyl chloride is a versatile sulfonylation reagent used in organic synthesis, particularly in the preparation of sulfonamides and sulfonate esters. Its reactive sulfonyl chloride group enables efficient coupling with amines, alcohols, and other nucleophiles, facilitating the introduction of the sulfonyl functional group into target molecules. The chloro and cyano substituents enhance its reactivity and provide additional sites for further functionalization. This compound is valued for its stability under controlled conditions and its utility in pharmaceutical and agrochemical intermediates. Proper handling is essential due to its moisture sensitivity and potential corrosiveness. Suitable for use in controlled laboratory environments with appropriate safety measures.
3-chloro-2-cyanobenzene-1-sulfonyl chloride structure
80023-25-2 structure
Product Name:3-chloro-2-cyanobenzene-1-sulfonyl chloride
CAS No:80023-25-2
MF:C7H3Cl2NO2S
MW:236.075218439102
CID:3385353
PubChem ID:18974428
Update Time:2025-05-26

3-chloro-2-cyanobenzene-1-sulfonyl chloride Chemical and Physical Properties

Names and Identifiers

    • BENZENESULFONYL CHLORIDE, 3-CHLORO-2-CYANO-
    • 3-chloro-2-cyanobenzene-1-sulfonyl chloride
    • 2-cyano-3-chlorobenzenesulphonylchloride
    • CS-0261102
    • EN300-77103
    • DTXSID301274710
    • 80023-25-2
    • AKOS011786427
    • 3-chloro-2-cyanobenzene-1-sulfonylchloride
    • 823-384-9
    • 2-cyano-3-chlorobenzenesulfonylchloride
    • SCHEMBL2570257
    • FJRVDPLJNHWGSE-UHFFFAOYSA-N
    • DTXCID101705260
    • 3-chloro-2-cyanobenzenesulfonyl chloride
    • DB-151579
    • Inchi: 1S/C7H3Cl2NO2S/c8-6-2-1-3-7(5(6)4-10)13(9,11)12/h1-3H
    • InChI Key: FJRVDPLJNHWGSE-UHFFFAOYSA-N
    • SMILES: C1(S(Cl)(=O)=O)=CC=CC(Cl)=C1C#N

Computed Properties

  • Exact Mass: 234.9261549Da
  • Monoisotopic Mass: 234.9261549Da
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 1
  • Complexity: 326
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.3
  • Topological Polar Surface Area: 66.3?2

3-chloro-2-cyanobenzene-1-sulfonyl chloride Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
C613213-25mg
3-chloro-2-cyanobenzene-1-sulfonyl chloride
80023-25-2
25mg
$ 50.00 2022-06-06
TRC
C613213-50mg
3-chloro-2-cyanobenzene-1-sulfonyl chloride
80023-25-2
50mg
$ 70.00 2022-06-06
TRC
C613213-250mg
3-chloro-2-cyanobenzene-1-sulfonyl chloride
80023-25-2
250mg
$ 275.00 2022-06-06
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1331772-50mg
3-Chloro-2-cyanobenzene-1-sulfonyl chloride
80023-25-2 95%
50mg
¥3732.00 2024-07-28
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1331772-100mg
3-Chloro-2-cyanobenzene-1-sulfonyl chloride
80023-25-2 95%
100mg
¥6470.00 2024-07-28
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1331772-250mg
3-Chloro-2-cyanobenzene-1-sulfonyl chloride
80023-25-2 95%
250mg
¥8582.00 2024-07-28
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1331772-500mg
3-Chloro-2-cyanobenzene-1-sulfonyl chloride
80023-25-2 95%
500mg
¥15627.00 2024-07-28
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1331772-1g
3-Chloro-2-cyanobenzene-1-sulfonyl chloride
80023-25-2 95%
1g
¥18718.00 2024-07-28
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1331772-2.5g
3-Chloro-2-cyanobenzene-1-sulfonyl chloride
80023-25-2 95%
2.5g
¥31406.00 2024-07-28
Enamine
EN300-77103-0.05g
3-chloro-2-cyanobenzene-1-sulfonyl chloride
80023-25-2 95%
0.05g
$173.0 2023-02-12

Additional information on 3-chloro-2-cyanobenzene-1-sulfonyl chloride

3-Chloro-2-Cyanobenzene-1-Sulfonyl Chloride: A Comprehensive Overview

3-Chloro-2-cyanobenzene-1-sulfonyl chloride, also known by its CAS number 80023-25-2, is a versatile and significant compound in the field of organic chemistry. This compound has garnered attention due to its unique structural properties and its potential applications in various industries. The molecule consists of a benzene ring substituted with a sulfonyl chloride group at position 1, a chlorine atom at position 3, and a cyano group at position 2. This combination of functional groups makes it a valuable intermediate in the synthesis of advanced materials and pharmaceuticals.

The sulfonyl chloride group in 3-chloro-2-cyanobenzene-1-sulfonyl chloride is highly reactive, making it an excellent electrophile in nucleophilic aromatic substitution reactions. Recent studies have highlighted its role in the development of novel heterocyclic compounds, which are crucial in drug discovery. For instance, researchers have utilized this compound to synthesize bioactive molecules with potential anti-inflammatory and anticancer properties. These findings underscore the importance of understanding the reactivity and regioselectivity of such compounds in complex chemical systems.

In addition to its role in organic synthesis, 3-chloro-2-cyanobenzene-1-sulfonyl chloride has been explored for its applications in materials science. The compound's ability to form stable sulfonamides under mild conditions has led to its use in the development of high-performance polymers and coatings. Recent advancements in polymer chemistry have demonstrated how these materials can exhibit enhanced thermal stability and mechanical strength, making them suitable for aerospace and automotive industries.

The cyano group present in the molecule also contributes to its electronic properties, making it an interesting candidate for use in electrochemical applications. Studies have shown that derivatives of this compound can serve as effective cathode materials in lithium-ion batteries, offering improved energy density and cycle life. As the demand for sustainable energy storage solutions grows, such innovations are expected to play a pivotal role in addressing global energy challenges.

From a safety standpoint, understanding the handling and storage requirements of 3-chloro-2-cyanobenzene-1-sulfonyl chloride is essential. While it is not classified as a hazardous material under standard conditions, proper precautions should be taken due to its reactive nature. Occupational exposure limits and recommended personal protective equipment have been established to ensure safe handling practices in industrial settings.

In conclusion, 3-chloro-2-cyanobenzene-1-sulfonyl chloride stands out as a multifaceted compound with diverse applications across various scientific disciplines. Its unique combination of functional groups positions it as a key player in modern chemical research and development. As ongoing studies continue to uncover new potentials for this compound, it is poised to make significant contributions to both academic and industrial advancements.

Recommended suppliers
Handan Zechi Trading Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangsu Kolod Food Ingredients Co.,ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangsu Kolod Food Ingredients Co.,ltd
鉅瀾化工科技(青島)有限公司
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
鉅瀾化工科技(青島)有限公司
Changzhou Guanjia Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Changzhou Guanjia Chemical Co., Ltd
Wuhan ChemNorm Biotech Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Wuhan ChemNorm Biotech Co.,Ltd.