Cas no 792886-64-7 ((2R)-2-(propan-2-yl)morpholine)

(2R)-2-(Propan-2-yl)morpholine is a chiral morpholine derivative characterized by its stereospecific (R)-configuration at the 2-position, where an isopropyl substituent enhances steric and electronic modulation. This compound serves as a versatile intermediate in asymmetric synthesis, particularly in the preparation of pharmaceuticals and agrochemicals, where enantioselectivity is critical. Its morpholine core offers stability and synthetic flexibility, while the isopropyl group influences reactivity and selectivity in nucleophilic or catalytic processes. The (R)-enantiomer is often preferred for its distinct stereochemical interactions in chiral environments. High purity and well-defined stereochemistry make it valuable for research and industrial applications requiring precise molecular control.
(2R)-2-(propan-2-yl)morpholine structure
792886-64-7 structure
Product Name:(2R)-2-(propan-2-yl)morpholine
CAS No:792886-64-7
MF:C7H15NO
MW:129.200102090836
MDL:MFCD14582703
CID:1023858
PubChem ID:53393364
Update Time:2025-10-12

(2R)-2-(propan-2-yl)morpholine Chemical and Physical Properties

Names and Identifiers

    • (R)-2-Isopropylmorpholine
    • (2R)-2-isopropyl-morpholine
    • (2R)-2-(propan-2-yl)morpholine
    • (2R)-2-(1-Methylethyl)morpholine (ACI)
    • Morpholine, 2-(1-methylethyl)-, (R)- (9CI)
    • (2R)-2-Propan-2-ylmorpholine
    • MFCD14582703
    • AMY21678
    • AKOS006378384
    • CS-0096525
    • BS-52997
    • A904249
    • SCHEMBL12206944
    • D75749
    • 792886-64-7
    • DTXSID40693879
    • (2R)-2-ISOPROPYLMORPHOLINE
    • MDL: MFCD14582703
    • Inchi: 1S/C7H15NO/c1-6(2)7-5-8-3-4-9-7/h6-8H,3-5H2,1-2H3/t7-/m0/s1
    • InChI Key: DNBOOEPFXFVICE-ZETCQYMHSA-N
    • SMILES: C([C@H]1OCCNC1)(C)C

Computed Properties

  • Exact Mass: 129.115
  • Monoisotopic Mass: 129.115
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 1
  • Complexity: 83
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 21.3A^2
  • XLogP3: 0.8

Experimental Properties

  • PSA: 21.26000
  • LogP: 0.95960

(2R)-2-(propan-2-yl)morpholine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A449036830-1g
(R)-2-Isopropylmorpholine
792886-64-7 95%
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$535.00 2023-09-01
Chemenu
CM163267-1g
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abcr
AB534047-250 mg
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abcr
AB534047-1 g
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abcr
AB534047-5 g
(R)-2-Isopropylmorpholine; .
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€1,261.00 2023-02-17
Apollo Scientific
OR308188-250mg
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£375.00 2023-09-02
Chemenu
CM163267-250mg
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Chemenu
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$150 2024-07-23
Chemenu
CM163267-5g
(R)-2-isopropylmorpholine
792886-64-7 95%
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$654 2024-07-23
eNovation Chemicals LLC
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(R)-2-Isopropylmorpholine
792886-64-7 97%
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Additional information on (2R)-2-(propan-2-yl)morpholine

Introduction to (2R)-2-(Propan-2-Yl)Morpholine (CAS No. 792886-64-7)

(2R)-2-(Propan-2-Yl)Morpholine, also known by its CAS number 792886-64-7, is a versatile organic compound that has garnered significant attention in the fields of organic chemistry, pharmacology, and materials science. This compound belongs to the morpholine family, which is a six-membered ring containing an oxygen atom and an amine group. The specific structure of (2R)-configuration introduces unique stereochemical properties, making it a valuable molecule for various applications.

The morpholine ring in (2R)-2-(Propan-2-Yl)Morpholine serves as a foundational framework for numerous chemical reactions. Recent studies have highlighted its potential as a building block in drug discovery, particularly in the development of bioactive compounds with enhanced pharmacokinetic profiles. Researchers have explored its ability to act as a chiral auxiliary, facilitating the synthesis of complex molecules with high enantioselectivity.

In terms of synthesis, (2R)-configuration has been achieved through various methods, including asymmetric catalysis and resolution techniques. These advancements have been documented in recent publications, underscoring the importance of stereocontrol in organic synthesis. The compound's stability under various reaction conditions makes it an attractive candidate for both academic and industrial applications.

Recent research has also focused on the application of (2R)-2-(Propan-2-Yl)Morpholine in polymer chemistry. Its ability to form stable amide bonds has led to its use in synthesizing novel polyamides with improved mechanical and thermal properties. These materials hold promise for use in high-performance textiles and advanced composites.

The compound's chiral nature has further been leveraged in asymmetric catalysis, where it serves as a ligand or catalyst in enantioselective reactions. Studies published in leading journals such as Nature Chemistry and Angewandte Chemie have demonstrated its effectiveness in promoting selective transformations, including aldol reactions and Michael additions.

In the pharmaceutical industry, (2R)-configuration has been incorporated into drug candidates targeting various therapeutic areas, including oncology and neurodegenerative diseases. Its role as a bioisostere has enabled the design of molecules with improved bioavailability and reduced toxicity profiles.

The environmental impact of synthesizing and using (CAS No. 792886-64-7) has also come under scrutiny. Green chemistry approaches have been proposed to minimize waste and energy consumption during its production. These efforts align with global sustainability goals and highlight the importance of eco-friendly practices in modern chemical synthesis.

In conclusion, (2R)-2-(Propan-2-Yl)Morpholine stands out as a multifaceted compound with diverse applications across multiple disciplines. Its unique stereochemical properties, coupled with recent advancements in synthesis and application techniques, position it as a key molecule for future innovations in science and technology.

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