Cas no 79082-64-7 ((-)-Corlumine)
(-)-Corlumine Chemical and Physical Properties
Names and Identifiers
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- (-)-Corlumine
- Furo(3,4-e)-1,3-benzodioxol-8(6H)-one, 6-((1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)-, (6S)-
- [ "" ]
- 79082-64-7
- Corlumine
- (6S)-6-[(1R)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one
- AKOS032949043
- (6S)-6-[(1R)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one (ACI)
- Furo[3,4-e]-1,3-benzodioxol-8(6H)-one, 6-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)-, [S-(R*,S*)]- (ZCI)
- (6S)-6-((1R)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl)-6H-furo(3,4-g)(1,3)benzodioxol-8-one
-
- Inchi: 1S/C21H21NO6/c1-22-7-6-11-8-15(24-2)16(25-3)9-13(11)18(22)19-12-4-5-14-20(27-10-26-14)17(12)21(23)28-19/h4-5,8-9,18-19H,6-7,10H2,1-3H3/t18-,19+/m1/s1
- InChI Key: SZDGAZFTAUFFQH-MOPGFXCFSA-N
- SMILES: CN1CCC2C=C(C(=CC=2[C@@H]1[C@H]1OC(=O)C2C3OCOC=3C=CC1=2)OC)OC
Computed Properties
- Exact Mass: 383.13700
- Monoisotopic Mass: 383.13688739g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 7
- Heavy Atom Count: 28
- Rotatable Bond Count: 3
- Complexity: 601
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 2
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.7
- Topological Polar Surface Area: 66.5?2
Experimental Properties
- Color/Form: Powder
- Density: 1.339±0.06 g/cm3 (20 oC 760 Torr),
- Melting Point: 158-160 °C (decomposition)
- Solubility: Almost insoluble (0.073 g/l) (25 o C),
- PSA: 66.46000
- LogP: 2.81110
(-)-Corlumine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TN3702-1 mg |
(-)-Corlumine |
79082-64-7 | 1mg |
¥2435.00 | 2022-04-26 | ||
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TN3702-5mg |
(-)-Corlumine |
79082-64-7 | 5mg |
¥ 3330 | 2023-09-08 | ||
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TN3702-1 mL * 10 mM (in DMSO) |
(-)-Corlumine |
79082-64-7 | 1 mL * 10 mM (in DMSO) |
¥ 3430 | 2023-09-08 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | C33800-5mg |
(S)-6-((R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)-[1,3]dioxolo[4,5-e]isobenzofuran-8(6H)-one |
79082-64-7 | ,HPLC≥98% | 5mg |
¥4800.0 | 2023-09-08 | |
| TargetMol Chemicals | TN3702-5mg |
(-)-Corlumine |
79082-64-7 | 5mg |
¥ 3330 | 2024-07-20 | ||
| TargetMol Chemicals | TN3702-5 mg |
(-)-Corlumine |
79082-64-7 | 98% | 5mg |
¥ 3,330 | 2023-07-11 | |
| TargetMol Chemicals | TN3702-1 mL * 10 mM (in DMSO) |
(-)-Corlumine |
79082-64-7 | 98% | 1 mL * 10 mM (in DMSO) |
¥ 3430 | 2023-09-15 | |
| A2B Chem LLC | AH57150-5mg |
(-)-Corlumine |
79082-64-7 | 98.0% | 5mg |
$594.00 | 2024-04-19 | |
| TargetMol Chemicals | TN3702-1 ml * 10 mm |
(-)-Corlumine |
79082-64-7 | 1 ml * 10 mm |
¥ 3430 | 2024-07-20 | ||
| A2B Chem LLC | AH57150-1mg |
(-)-Corlumine |
79082-64-7 | >98% | 1mg |
$599.00 | 2023-12-30 |
(-)-Corlumine Related Literature
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Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
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Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361
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Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389
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Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
Additional information on (-)-Corlumine
Exploring the Unique Properties and Applications of (-)-Corlumine (CAS No. 79082-64-7)
(-)-Corlumine (CAS No. 79082-64-7) is a naturally occurring alkaloid that has garnered significant attention in the fields of pharmacology and organic chemistry. This compound, known for its chiral structure and bioactive properties, is derived from certain plant species and has been studied for its potential therapeutic applications. Researchers are particularly interested in its stereospecific interactions, which make it a valuable subject for drug discovery and development.
The molecular structure of (-)-Corlumine features a complex arrangement of carbon, hydrogen, nitrogen, and oxygen atoms, contributing to its unique chemical behavior. Its optical activity and enantiomeric purity are critical factors in its biological activity, distinguishing it from its (+)-enantiomer. This specificity is why scientists are exploring its role in targeted therapies, particularly in neurological and metabolic disorders.
In recent years, the demand for natural alkaloids like (-)-Corlumine has surged due to their potential in alternative medicine and green chemistry. With growing interest in sustainable sourcing and eco-friendly extraction methods, this compound aligns well with modern trends in pharmaceutical research. Its low toxicity profile and compatibility with biodegradable formulations further enhance its appeal.
One of the most frequently asked questions about (-)-Corlumine is its mechanism of action. Preliminary studies suggest it may interact with specific neurotransmitter systems, making it a candidate for treating conditions like anxiety and chronic pain. Additionally, its anti-inflammatory properties have sparked interest in its use for autoimmune diseases, a hot topic in current medical research.
The synthesis of (-)-Corlumine remains a challenge due to its complex stereochemistry. However, advancements in asymmetric synthesis and enzymatic catalysis have opened new pathways for its production. These innovations are crucial for meeting the rising demand while maintaining high purity standards, a key concern for pharmaceutical applications.
From a market perspective, (-)-Corlumine is gaining traction in the nutraceutical and cosmeceutical industries. Its potential as a skin brightening agent and anti-aging compound has led to its inclusion in high-end skincare formulations. Consumers are increasingly searching for plant-derived active ingredients, and this compound fits perfectly into this trend.
For researchers and manufacturers, ensuring the consistent quality of (-)-Corlumine is paramount. Analytical techniques such as HPLC and mass spectrometry are commonly employed to verify its purity and stability. These methods are essential for compliance with regulatory standards, particularly in markets with strict guidelines for natural products.
In conclusion, (-)-Corlumine (CAS No. 79082-64-7) represents a fascinating intersection of natural product chemistry and modern therapeutics. Its multifunctional properties, combined with its alignment with sustainability trends, position it as a compound with significant future potential. As research continues to uncover its full range of applications, it is likely to remain a focal point in both academic and industrial settings.
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