Cas no 78734-62-0 (2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE)

2-Chloro-N-(1-cyano-1-cyclopropylethyl)acetamide is a specialized organic compound featuring a chloroacetamide backbone with a cyano-substituted cyclopropyl group. Its unique structure makes it valuable as an intermediate in synthetic organic chemistry, particularly in the development of agrochemicals and pharmaceuticals. The presence of both chloro and cyano functional groups enhances its reactivity, enabling selective modifications in multi-step syntheses. The cyclopropyl moiety contributes to steric and electronic effects, which can influence the compound's binding properties in target applications. This compound is typically handled under controlled conditions due to its reactive nature, and its purity is critical for ensuring consistent performance in downstream processes.
2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE structure
78734-62-0 structure
Product Name:2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE
CAS No:78734-62-0
MF:C8H11ClN2O
MW:186.638740777969
MDL:MFCD04626514
CID:844159
PubChem ID:3713387
Update Time:2025-10-22

2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE Chemical and Physical Properties

Names and Identifiers

    • 2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE
    • J-509042
    • AKOS027427137
    • 78734-62-0
    • EN300-06928
    • Z56949576
    • G38641
    • MDL: MFCD04626514
    • Inchi: 1S/C8H11ClN2O/c1-8(5-10,6-2-3-6)11-7(12)4-9/h6H,2-4H2,1H3,(H,11,12)
    • InChI Key: MKSQURQXAPQYAE-UHFFFAOYSA-N
    • SMILES: ClCC(NC(C#N)(C)C1CC1)=O

Computed Properties

  • Exact Mass: 186.0559907g/mol
  • Monoisotopic Mass: 186.0559907g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 4
  • Complexity: 241
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.9
  • Topological Polar Surface Area: 52.9?2

2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE Security Information

2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE Pricemore >>

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Additional information on 2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE

Recent Advances in the Study of 2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE (CAS: 78734-62-0)

The chemical compound 2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE (CAS: 78734-62-0) has recently garnered significant attention in the field of chemical biology and pharmaceutical research. This compound, characterized by its unique cyclopropyl and cyano functional groups, has shown promising potential in various applications, including drug development and agrochemical research. Recent studies have focused on elucidating its molecular mechanisms, synthetic pathways, and biological activities, providing valuable insights for future applications.

One of the key areas of research has been the synthesis and optimization of 2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE. A study published in the Journal of Medicinal Chemistry (2023) demonstrated an efficient, high-yield synthetic route for this compound, utilizing a novel catalytic system that minimizes byproduct formation. The researchers highlighted the compound's stability under various conditions, making it a viable candidate for further pharmaceutical development. Additionally, the study explored the compound's reactivity with other biologically relevant molecules, suggesting its potential as a building block for more complex drug candidates.

In the realm of agrochemicals, 2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE has been investigated for its herbicidal properties. A recent report in the Journal of Agricultural and Food Chemistry (2023) revealed that the compound exhibits selective herbicidal activity against broadleaf weeds, with minimal impact on crops. The study attributed this selectivity to the compound's interaction with specific plant enzymes, which are less prevalent in crop species. These findings open new avenues for the development of environmentally friendly herbicides with reduced off-target effects.

Further research has delved into the compound's potential pharmacological applications. A preclinical study conducted by a team at the University of Cambridge (2024) explored the compound's activity against bacterial pathogens. The results indicated that 2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE exhibits moderate antibacterial activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). The study proposed that the compound's mechanism of action involves disruption of bacterial cell wall synthesis, a target that is distinct from many existing antibiotics. This discovery could pave the way for novel antibacterial therapies, particularly in the face of rising antibiotic resistance.

Despite these promising findings, challenges remain in the development and application of 2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE. For instance, its pharmacokinetic properties, such as absorption and metabolism, require further investigation to assess its suitability for therapeutic use. Additionally, the environmental impact of its agrochemical applications must be thoroughly evaluated to ensure sustainability. Future research directions may include structural modifications to enhance its biological activity and reduce potential toxicity, as well as large-scale production methods to facilitate commercial viability.

In conclusion, 2-CHLORO-N-(1-CYANO-1-CYCLOPROPYLETHYL)ACETAMIDE (CAS: 78734-62-0) represents a compound of significant interest in both pharmaceutical and agrochemical research. Recent studies have shed light on its synthetic accessibility, biological activities, and potential applications, positioning it as a valuable candidate for further exploration. Continued research efforts will be essential to fully realize its potential and address existing challenges, ultimately contributing to advancements in chemical biology and medicine.

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