Cas no 78197-27-0 (4-Fluoropiperidine)
4-Fluoropiperidine is a fluorinated heterocyclic compound featuring a piperidine ring substituted with a fluorine atom at the 4-position. This structural modification enhances its utility as a versatile intermediate in pharmaceutical and agrochemical synthesis. The fluorine atom imparts increased metabolic stability and lipophilicity, making it valuable for the development of bioactive molecules. Its reactivity allows for further functionalization, enabling applications in medicinal chemistry, particularly in the design of CNS-targeting drugs and enzyme inhibitors. The compound is typically supplied as a high-purity liquid or solid, ensuring consistent performance in synthetic workflows. Proper handling under inert conditions is recommended due to its sensitivity to moisture and air.
4-Fluoropiperidine structure
Product Name:4-Fluoropiperidine
CAS No:78197-27-0
MF:C5H10FN
MW:103.138004779816
MDL:MFCD03093851
CID:551763
PubChem ID:2759159
Update Time:2025-05-28
4-Fluoropiperidine Chemical and Physical Properties
Names and Identifiers
-
- 4-Fluoropiperidine
- 2-Pyridinecarboxylic acid,4-fluoro
- 4-FLUORO-2-PYRIDINECARBOXYLIC ACID
- 4-Fluoropicolinic acid
- 4-Fluoropiperidin
- 4-fluoropyridin-2-carboxylic acid
- 4-Fluorpiperidin
- 78197-27-0
- MFCD03093851
- I11481
- AKOS005064106
- SCHEMBL9503
- DTXSID30999438
- CS-0101735
- 4-fluoro-piperidine
- QBLLOOKBLTTXHB-UHFFFAOYSA-N
- Piperidine, 4-fluoro-
- 4-Fluoropyperidine
- EN300-41396
- SY020129
- CHEMBL1162291
- 4-fluoropiperdine
- FT-0692487
- 4-Fluoro-piperidinium
- BS-24472
- AB13264
- A852875
- BBL102081
- STL555880
-
- MDL： MFCD03093851
- Inchi： 1S/C5H10FN/c6-5-1-3-7-4-2-5/h5,7H,1-4H2
- InChI Key： QBLLOOKBLTTXHB-UHFFFAOYSA-N
- SMILES： FC1CCNCC1
Computed Properties
- Exact Mass: 103.08000
- Monoisotopic Mass: 103.08
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 7
- Rotatable Bond Count: 0
- Complexity: 50
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 12A^2
- XLogP3: 0.7
Experimental Properties
- Density: 0.97±0.1 g/cm3 (20 oC 760 Torr),
- Boiling Point: 120.2±33.0 oC (760 Torr),
- Flash Point: 26.5±25.4 oC,
- Refractive Index: 1.421
- Solubility: Soluble (106 g/l) (25 o C),
- PSA: 12.03000
- LogP: 1.03670
4-Fluoropiperidine Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
4-Fluoropiperidine Customs Data
- HS CODE：2933399090
- Customs Data：
China Customs Code:
2933399090Overview:
2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
4-Fluoropiperidine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | F594558-10mg |
4-Fluoropiperidine |
78197-27-0 | 10mg |
$ 50.00 | 2022-06-04 | ||
| TRC | F594558-50mg |
4-Fluoropiperidine |
78197-27-0 | 50mg |
$ 65.00 | 2022-06-04 | ||
| TRC | F594558-100mg |
4-Fluoropiperidine |
78197-27-0 | 100mg |
$ 80.00 | 2022-06-04 | ||
| eNovation Chemicals LLC | Y1198624-1g |
4-Fluoropiperidine |
78197-27-0 | 95% | 1g |
$190 | 2023-09-03 | |
| eNovation Chemicals LLC | Y1198624-5g |
4-Fluoropiperidine |
78197-27-0 | 98% | 5g |
$130 | 2024-07-20 | |
| eNovation Chemicals LLC | K92254-500mg |
4-fluoropiperidine |
78197-27-0 | 95% | 500mg |
$780 | 2024-05-25 | |
| eNovation Chemicals LLC | K92254-1g |
4-fluoropiperidine |
78197-27-0 | 95% | 1g |
$980 | 2024-05-25 | |
| abcr | AB460481-500 mg |
4-Fluoropiperidine, 95%; . |
78197-27-0 | 95% | 500MG |
€160.40 | 2022-03-01 | |
| abcr | AB460481-1 g |
4-Fluoropiperidine, 95%; . |
78197-27-0 | 95% | 1g |
€226.40 | 2022-03-01 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-YE963-50mg |
4-Fluoropiperidine |
78197-27-0 | 98+% | 50mg |
153.0CNY | 2021-07-14 |
4-Fluoropiperidine Related Literature
-
Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
-
Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
-
Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389
-
Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
78197-27-0 (4-Fluoropiperidine) Related Products
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- 21987-29-1(4,4-Difluoropiperidine)
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