Cas no 78056-39-0 (4,5-difluoro-2-nitro-aniline)

4,5-Difluoro-2-nitro-aniline is a fluorinated aromatic amine derivative with the molecular formula C?H?F?N?O?. This compound is characterized by the presence of two fluorine atoms at the 4 and 5 positions and a nitro group at the 2 position of the aniline ring. Its unique substitution pattern enhances reactivity and selectivity, making it a valuable intermediate in organic synthesis, particularly for pharmaceuticals and agrochemicals. The electron-withdrawing effects of the fluorine and nitro groups contribute to its utility in nucleophilic substitution and coupling reactions. High purity and stability under standard conditions ensure consistent performance in research and industrial applications.
4,5-difluoro-2-nitro-aniline structure
4,5-difluoro-2-nitro-aniline structure
Product Name:4,5-difluoro-2-nitro-aniline
CAS No:78056-39-0
MF:C6H4F2N2O2
MW:174.104968070984
MDL:MFCD00010876
CID:59939
PubChem ID:24857587
Update Time:2025-06-09

4,5-difluoro-2-nitro-aniline Chemical and Physical Properties

Names and Identifiers

    • 4,5-DIFLUORO-2-NITROANILINE
    • 3,4-Difluoro-6-nitroaniline
    • 4,5-Difluoro-2-nitrophenylamine
    • 2-nitro-3,4-difluoroaniline
    • 2-nitro-4,5-difluoroaniline
    • 4,5-difluoro-2-nitro-aniline
    • 4,5-difluoro-2-nitrobenzenamine
    • 4,5-difluoro-2-nitro-phenylamine
    • Benzenamine, 4,5-difluoro-2-nitro-
    • WDMCABATCGQAKK-UHFFFAOYSA-N
    • 2-Amino-4,5-difluoronitrobenzene
    • NSC402976
    • PubChem2121
    • 4,5-difluoro2-nitroaniline
    • 4,5-difluoro-2nitroaniline
    • KSC495K8D
    • CL8438
    • EN300-27866
    • BP-20379
    • GS-3399
    • MFCD00010876
    • CCG-302571
    • NS00126256
    • FT-0601439
    • NSC 402976
    • CS-W008348
    • AC-3677
    • SCHEMBL199359
    • DTXSID00228702
    • A19758
    • CHEMBL4459918
    • 78056-39-0
    • D3644
    • NSC-402976
    • Z235347007
    • 4,5-Difluoro-2-nitroaniline, 98%
    • AKOS001393903
    • AM20061125
    • DB-006585
    • DTXCID10151193
    • SY004058
    • MDL: MFCD00010876
    • Inchi: 1S/C6H4F2N2O2/c7-3-1-5(9)6(10(11)12)2-4(3)8/h1-2H,9H2
    • InChI Key: WDMCABATCGQAKK-UHFFFAOYSA-N
    • SMILES: FC1C(=CC(=C(C=1)[N+](=O)[O-])N)F
    • BRN: 2723242

Computed Properties

  • Exact Mass: 174.02400
  • Monoisotopic Mass: 174.024
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 0
  • Complexity: 185
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Molecular Weight: 174.10
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 1.4
  • Topological Polar Surface Area: 71.8

Experimental Properties

  • Color/Form: Yellow powder.
  • Density: 1.554
  • Melting Point: 106.0 to 110.0 deg-C
  • Boiling Point: 308.1 °C at 760 mmHg
  • Flash Point: 140.1℃
  • Refractive Index: 1.575
  • PSA: 71.84000
  • LogP: 2.55960
  • Solubility: Not determined

4,5-difluoro-2-nitro-aniline Security Information

  • Symbol: GHS07
  • Prompt:warning
  • Signal Word:Warning
  • Hazard Statement: H315,H319,H335
  • Warning Statement: P261,P305+P351+P338
  • Hazardous Material transportation number:2811
  • WGK Germany:3
  • Hazard Category Code: 36/37/38
  • Safety Instruction: S26
  • FLUKA BRAND F CODES:10
  • Hazardous Material Identification: Xi
  • Packing Group:III
  • Hazard Level:6.1(b)
  • Risk Phrases:R36/37/38
  • Packing Group:III
  • Safety Term:6.1(b)
  • HazardClass:6.1(b)
  • PackingGroup:III
  • Storage Condition:Keep in dark place,Inert atmosphere,Room temperature

4,5-difluoro-2-nitro-aniline Customs Data

  • HS CODE:2921420090
  • Customs Data:

    China Customs Code:

    2921420090

    Overview:

    2921420090 Other aniline derivatives and their salts. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

4,5-difluoro-2-nitro-aniline Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI XIAN DING Biotechnology Co., Ltd.
D3644-25g
4,5-difluoro-2-nitro-aniline
78056-39-0 98.0%(GC)
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¥690.0 2022-08-30
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4,5-difluoro-2-nitro-aniline Production Method

4,5-difluoro-2-nitro-aniline Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:78056-39-0)4,5-DIFLUORO-2-NITROANILINE
Order Number:sfd7060
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:34
Price ($):discuss personally
Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:78056-39-0)4,5-difluoro-2-nitro-aniline
Order Number:A19758
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 16:01
Price ($):435.0

Additional information on 4,5-difluoro-2-nitro-aniline

Comprehensive Overview of 4,5-Difluoro-2-nitroaniline (CAS No. 78056-39-0): Properties, Applications, and Industry Insights

4,5-Difluoro-2-nitroaniline (CAS 78056-39-0) is a fluorinated aromatic compound widely recognized for its role as a versatile intermediate in organic synthesis. With the molecular formula C6H4F2N2O2, this nitroaniline derivative features two fluorine atoms at the 4 and 5 positions, enhancing its reactivity and making it valuable for constructing complex molecules. Its fluoro-nitroaniline structure is pivotal in pharmaceuticals, agrochemicals, and advanced material research, aligning with growing trends in sustainable chemistry and precision manufacturing.

The compound’s thermal stability and solubility in polar solvents (e.g., DMSO or ethanol) make it suitable for controlled reactions under mild conditions. Researchers frequently explore its use in cross-coupling reactions, a hotspot in modern catalysis studies, to develop novel heterocyclic compounds. Recent publications highlight its utility in synthesizing fluorescent dyes and bioactive molecules, addressing demands from the life sciences sector for high-purity intermediates.

Environmental and regulatory trends have spurred interest in green synthesis methods for 4,5-difluoro-2-nitroaniline. Innovations like microwave-assisted reactions or enzymatic catalysis reduce waste and energy consumption—a response to the industry’s push for sustainable chemical processes. Analytical techniques such as HPLC and GC-MS ensure quality control, meeting stringent standards for impurities (<0.5%), a common query among quality assurance professionals.

From an SEO perspective, users often search for "4,5-difluoro-2-nitroaniline suppliers," "CAS 78056-39-0 safety data," or "nitroaniline derivatives applications." Addressing these, the compound’s non-hazardous handling (under standard conditions) and compatibility with GMP-certified facilities are key selling points. Additionally, its role in OLED materials and photonics taps into the booming electronics market, where fluorinated compounds improve device efficiency.

In summary, 4,5-Difluoro-2-nitroaniline bridges academic research and industrial applications, driven by advancements in fluorine chemistry and eco-friendly synthesis. Its adaptability to diverse reaction schemes positions it as a critical building block for future innovations, from drug discovery to smart materials.

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:78056-39-0)4,5-DIFLUORO-2-NITROANILINE
sfd7060
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email
Amadis Chemical Company Limited
(CAS:78056-39-0)4,5-difluoro-2-nitro-aniline
A19758
Purity:99%
Quantity:500g
Price ($):435.0
Email