Cas no 78046-28-3 (5-Chloro-2,4-dimethoxybenzene-1-sulfonyl Chloride)
5-Chloro-2,4-dimethoxybenzene-1-sulfonyl chloride is a versatile sulfonylation reagent used in organic synthesis, particularly in the preparation of sulfonamides and sulfonate esters. Its key advantages include high reactivity due to the sulfonyl chloride group, enabling efficient derivatization under mild conditions. The chloro and dimethoxy substituents enhance its stability and selectivity in electrophilic reactions. This compound is valuable in pharmaceutical and agrochemical research, where it serves as a key intermediate for constructing complex molecules. Its well-defined structure and consistent purity make it suitable for precision applications in medicinal chemistry and material science. Proper handling is required due to its moisture sensitivity.
78046-28-3 structure
Product Name:5-Chloro-2,4-dimethoxybenzene-1-sulfonyl Chloride
CAS No:78046-28-3
MF:C8H8Cl2O4S
MW:271.117719650269
MDL:MFCD08687267
CID:535086
PubChem ID:12712817
Update Time:2025-10-13
5-Chloro-2,4-dimethoxybenzene-1-sulfonyl Chloride Chemical and Physical Properties
Names and Identifiers
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- Benzenesulfonyl chloride, 5-chloro-2,4-dimethoxy-
- 5-Chloro-2,4-dimethoxybenzenesulfonyl chloride
- 5-CHLORO-2,4-DIMETHOXY-BENZENESULFONYL CHLORIDE
- 5-chloro 2,4-dimethoxy benzenesulfonyl chloride
- 5-chloro-2,4-dimethoxybenzene-1-sulfonyl chloride
- 5-chloro-2,4-dimethoxybenzenesulphonyl chloride
- 5-chloro-2,4-dimethoxybenzensulfonyl chloride
- chloro(5-chloro-2,4-dimethoxyphenyl)sulfone
- EN300-250118
- SCHEMBL10570597
- D86067
- 78046-28-3
- FT-0678016
- 5-Chloro-2,4-dimethoxybenzenesulfonyl chloride, AldrichCPR
- AKOS000301043
- 3-(1,3-Oxazol-5-yl)benzenesulfonylchloride
- 5-chloro-2,4-dimethoxybenzene-1-sulfonylchloride
- DTXSID50507711
- 5-Chloro-2,4-dimethoxybenzene-1-sulfonyl Chloride
-
- MDL： MFCD08687267
- Inchi： 1S/C8H8Cl2O4S/c1-13-6-4-7(14-2)8(3-5(6)9)15(10,11)12/h3-4H,1-2H3
- InChI Key： HXTZVKXMOKCJPE-UHFFFAOYSA-N
- SMILES： ClC1C(=CC(=C(C=1)S(=O)(=O)Cl)OC)OC
Computed Properties
- Exact Mass: 269.95200
- Monoisotopic Mass: 269.9520353g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 15
- Rotatable Bond Count: 3
- Complexity: 300
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.5
- Topological Polar Surface Area: 61?2
Experimental Properties
- PSA: 60.98000
- LogP: 3.36550
5-Chloro-2,4-dimethoxybenzene-1-sulfonyl Chloride Security Information
-
Hazardous Material Identification：
- HazardClass：IRRITANT
5-Chloro-2,4-dimethoxybenzene-1-sulfonyl Chloride Customs Data
- HS CODE：2909309090
- Customs Data：
China Customs Code:
2909309090Overview:
2909309090 Other aromatic ethers and their halogenated derivatives\sulfonation\Nitrated derivative(Including nitrosative derivatives).Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:5.5%.general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
5-Chloro-2,4-dimethoxybenzene-1-sulfonyl Chloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A019089225-5g |
5-Chloro-2,4-dimethoxybenzene-1-sulfonyl chloride |
78046-28-3 | 95% | 5g |
$515.00 | 2023-09-01 | |
| TRC | T777008-10mg |
5-Chloro-2,4-dimethoxybenzene-1-sulfonyl Chloride |
78046-28-3 | 10mg |
$ 50.00 | 2022-06-02 | ||
| TRC | T777008-50mg |
5-Chloro-2,4-dimethoxybenzene-1-sulfonyl Chloride |
78046-28-3 | 50mg |
$ 160.00 | 2022-06-02 | ||
| TRC | T777008-100mg |
5-Chloro-2,4-dimethoxybenzene-1-sulfonyl Chloride |
78046-28-3 | 100mg |
$ 230.00 | 2022-06-02 | ||
| Enamine | EN300-250118-1g |
5-chloro-2,4-dimethoxybenzene-1-sulfonyl chloride |
78046-28-3 | 95% | 1g |
$528.0 | 2023-09-15 | |
| Enamine | EN300-250118-5g |
5-chloro-2,4-dimethoxybenzene-1-sulfonyl chloride |
78046-28-3 | 95% | 5g |
$1530.0 | 2023-09-15 | |
| Enamine | EN300-250118-10g |
5-chloro-2,4-dimethoxybenzene-1-sulfonyl chloride |
78046-28-3 | 95% | 10g |
$2269.0 | 2023-09-15 | |
| Enamine | EN300-250118-0.05g |
5-chloro-2,4-dimethoxybenzene-1-sulfonyl chloride |
78046-28-3 | 95% | 0.05g |
$101.0 | 2024-06-19 | |
| Enamine | EN300-250118-0.1g |
5-chloro-2,4-dimethoxybenzene-1-sulfonyl chloride |
78046-28-3 | 95% | 0.1g |
$152.0 | 2024-06-19 | |
| Enamine | EN300-250118-0.25g |
5-chloro-2,4-dimethoxybenzene-1-sulfonyl chloride |
78046-28-3 | 95% | 0.25g |
$216.0 | 2024-06-19 |
5-Chloro-2,4-dimethoxybenzene-1-sulfonyl Chloride Related Literature
-
Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026
-
Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
-
3. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
-
Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389
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