Cas no 77924-01-7 (N,N-Diisopropylnicotinamide)

N,N-Diisopropylnicotinamide is a nicotinamide derivative characterized by its diisopropyl substitution on the nitrogen atoms. This compound is primarily utilized in organic synthesis and pharmaceutical research due to its role as a versatile intermediate. Its structural features, including the amide functionality and sterically hindered isopropyl groups, contribute to its stability and reactivity in selective transformations. The compound is particularly valuable in the development of bioactive molecules and coordination chemistry, where its electron-donating properties and steric effects can influence reaction outcomes. It is typically handled under inert conditions to preserve its integrity. High purity grades are available for research applications.
N,N-Diisopropylnicotinamide structure
N,N-Diisopropylnicotinamide structure
Product Name:N,N-Diisopropylnicotinamide
CAS No:77924-01-7
MF:C12H18N2O
MW:206.284122943878
CID:59934
PubChem ID:4279764
Update Time:2025-05-21

N,N-Diisopropylnicotinamide Chemical and Physical Properties

Names and Identifiers

    • N,N-Diisopropylnicotinamide
    • N,N-di(propan-2-yl)pyridine-3-carboxamide
    • N,N-Diisopropyl-3-pyridinecarboxamide
    • nicotineamide
    • nicotinic acid diisopropylamide
    • Nicotinsaeure-diisopropylamid
    • N,N-bis(propan-2-yl)pyridine-3-carboxamide
    • 77924-01-7
    • N,N-Diisopropylninicotinamide
    • SCHEMBL1591435
    • AKOS003855747
    • DTXSID10401509
    • 3-Pyridinecarboxamide,N,N-bis(1-methylethyl)-
    • FT-0707888
    • N,N-diisopropylpyridine-3-carboxamide
    • Inchi: 1S/C12H18N2O/c1-9(2)14(10(3)4)12(15)11-6-5-7-13-8-11/h5-10H,1-4H3
    • InChI Key: RHBRDTJXGNWOGY-UHFFFAOYSA-N
    • SMILES: O=C(C1C=NC=CC=1)N(C(C)C)C(C)C

Computed Properties

  • Exact Mass: 206.14200
  • Monoisotopic Mass: 206.142
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 3
  • Complexity: 206
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.1
  • Topological Polar Surface Area: 33.2A^2

Experimental Properties

  • Density: 1.007
  • Boiling Point: 326.2 °C at 760 mmHg
  • Flash Point: 151.1 °C
  • PSA: 33.20000
  • LogP: 2.34060

N,N-Diisopropylnicotinamide Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

N,N-Diisopropylnicotinamide Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
N267665-100mg
N,N-Diisopropylnicotinamide
77924-01-7
100mg
$ 170.00 2022-06-03
TRC
N267665-250mg
N,N-Diisopropylnicotinamide
77924-01-7
250mg
$ 355.00 2022-06-03
TRC
N267665-500mg
N,N-Diisopropylnicotinamide
77924-01-7
500mg
$ 560.00 2022-06-03

N,N-Diisopropylnicotinamide Related Literature

Additional information on N,N-Diisopropylnicotinamide

Comprehensive Overview of N,N-Diisopropylnicotinamide (CAS No. 77924-01-7): Properties, Applications, and Industry Insights

N,N-Diisopropylnicotinamide (CAS No. 77924-01-7) is a specialized organic compound belonging to the class of nicotinamide derivatives. With its unique molecular structure, this compound has garnered significant attention in pharmaceutical research, agrochemical development, and material science. The growing demand for high-purity nicotinamide derivatives in modern applications underscores the importance of understanding this compound's characteristics and potential.

Chemically, N,N-Diisopropylnicotinamide features a pyridine core substituted with a carboxamide group at the 3-position, where the nitrogen atoms are further modified with isopropyl groups. This structural configuration contributes to its distinct physicochemical properties, including solubility in organic solvents and thermal stability up to 200°C. Researchers particularly value its molecular versatility, which allows for various synthetic modifications in drug discovery pipelines.

In pharmaceutical applications, N,N-Diisopropylnicotinamide serves as a crucial intermediate for developing novel therapeutic agents. Recent studies highlight its potential in creating enzyme modulators and receptor-targeting compounds, addressing current industry focus areas such as metabolic disorders and neurological conditions. The compound's balanced lipophilicity makes it particularly valuable for optimizing drug bioavailability, a key challenge in modern pharmacokinetic research.

The agrochemical sector has shown increasing interest in CAS 77924-01-7 derivatives for developing next-generation crop protection agents. Its molecular framework allows for the creation of compounds with improved environmental profiles, aligning with the global shift toward sustainable agriculture practices. Manufacturers are exploring its use in formulations that meet stringent regulatory requirements while maintaining efficacy against resistant pest strains.

Material science innovations have also benefited from N,N-Diisopropylnicotinamide's properties. Its application in functional polymer development and coordination chemistry has opened new possibilities for advanced materials with tailored characteristics. Researchers are particularly excited about its potential in creating smart materials that respond to environmental stimuli, a rapidly growing field in materials engineering.

Quality control and analytical characterization of 77924-01-7 present specific challenges that require advanced techniques. Modern laboratories employ HPLC-MS and NMR spectroscopy to ensure purity and verify structural integrity. The compound's stability under various storage conditions makes it relatively easy to handle, though proper chemical storage protocols should always be followed to maintain optimal quality.

The market for N,N-Diisopropylnicotinamide reflects broader trends in specialty chemicals demand. With increasing investment in precision medicine and green chemistry initiatives, industry analysts project steady growth for this niche segment. Current research focuses on developing more efficient synthetic routes to improve yield and reduce production costs, addressing common questions about process optimization in fine chemical manufacturing.

Environmental and safety considerations for CAS 77924-01-7 follow standard protocols for handling organic compounds. While not classified as hazardous under normal conditions, proper laboratory safety measures should always be implemented. The compound's environmental fate and biodegradability profile have become important discussion points as industries emphasize eco-friendly chemistry practices.

Future research directions for N,N-Diisopropylnicotinamide include exploring its potential in catalysis and energy storage applications. The compound's electron-rich structure makes it an interesting candidate for developing novel redox-active materials, particularly in the context of renewable energy technologies. These emerging applications demonstrate how traditional chemical building blocks can find new relevance in cutting-edge scientific fields.

For researchers and industry professionals seeking detailed technical information about 77924-01-7, comprehensive spectral data and physicochemical parameters are available through reputable chemical databases. The compound's well-documented characteristics and growing application portfolio position it as a valuable tool in multiple scientific disciplines, from medicinal chemistry to advanced material design.

Recommended suppliers
ASIACHEM I&E (JIANGSU) CO., LTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
ASIACHEM I&E (JIANGSU) CO., LTD
Suzhou Genelee Bio-Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Suzhou Genelee Bio-Technology Co., Ltd.
Jiangxi Boyang Pharmaceutical Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangxi Boyang Pharmaceutical Chemical Co., Ltd
Inner Mongolia Xinhong Biological Technology Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Inner Mongolia Xinhong Biological Technology Co., Ltd
Yunnanjiuzhen
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Yunnanjiuzhen