Cas no 7778-85-0 (1,2-dimethoxypropane)

1,2-Dimethoxypropane (CAS 77-76-9) is a clear, colorless liquid with the molecular formula C?H??O?. It is a versatile solvent and reagent, particularly valued for its role as a protecting group for diols and as a dehydrating agent in organic synthesis. Its low water solubility and ability to form azeotropes make it useful in moisture-sensitive reactions. The compound exhibits good stability under neutral and basic conditions, while remaining reactive under acidic conditions, enabling controlled deprotection. Its relatively low boiling point (90–92°C) facilitates easy removal post-reaction. 1,2-Dimethoxypropane is commonly employed in pharmaceuticals, fine chemicals, and polymer applications due to its efficiency in acetal formation and inertness toward many functional groups.
1,2-dimethoxypropane structure
1,2-dimethoxypropane structure
Product Name:1,2-dimethoxypropane
CAS No:7778-85-0
MF:C5H12O2
MW:104.147582054138
MDL:MFCD00010331
CID:47799
PubChem ID:253659876
Update Time:2025-10-12

1,2-dimethoxypropane Chemical and Physical Properties

Names and Identifiers

    • 1,2-dimethoxypropane
    • 1,2-dimethoxy-1-methylethane
    • 2,3-dimethoxypropane
    • MeOCH2CH(Me)OMe
    • Propane,1,2-dimethoxy
    • Propylene glycol dimethyl ether
    • 1,2-Dimethoxypropane, >=99%
    • AKOS015904500
    • LS-13095
    • J-503828
    • MFCD00010331
    • EC 404-630-0
    • D90270
    • NS00005619
    • SCHEMBL65799
    • Propane, 1,2-dimethoxy-
    • D4281
    • DTXSID60871197
    • 7778-85-0
    • DTXCID40818868
    • MDL： MFCD00010331
    • Inchi： 1S/C5H12O2/c1-5(7-3)4-6-2/h5H,4H2,1-3H3
    • InChI Key： LEEANUDEDHYDTG-UHFFFAOYSA-N
    • SMILES： O(C)C(C)COC

Computed Properties

  • Exact Mass: 104.08400
  • Monoisotopic Mass: 104.08373
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 7
  • Rotatable Bond Count: 3
  • Complexity: 37.1
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 18.5
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing

Experimental Properties

  • Color/Form: Colorless, low odor transparent liquid with moderate evaporation rate and strong solubility and coupling.
  • Density: 0.855?g/mL?at 25?°C(lit.)
  • Boiling Point: 96°C(lit.)
  • Flash Point: Fahrenheit: 33.8 ° f
    Celsius: 1 ° c
  • Refractive Index: n20/D 1.3835(lit.)
  • PSA: 18.46000
  • LogP: 0.66770
  • Vapor Pressure: 40 mmHg ( 20 °C)
  • Solubility: Not determined

1,2-dimethoxypropane Security Information

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1,2-dimethoxypropane Production Method

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Suzhou Senfeida Chemical Co., Ltd
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(CAS:7778-85-0)1,2-Dimethoxypropane
Order Number:sfd8170
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:34
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Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:7778-85-0)丙二醇二甲醚
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Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:55
Price ($):discuss personally

1,2-dimethoxypropane Related Literature

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Additional information on 1,2-dimethoxypropane

1,2-Dimethoxypropane (CAS No. 7778-85-0): A Comprehensive Overview

1,2-Dimethoxypropane (CAS No. 7778-85-0) is a versatile organic compound with the molecular formula C5H12O2. It belongs to the class of ethers and is widely recognized for its applications in organic synthesis and industrial processes. This compound is also known as dimethoxymethane or methoxypropane, and its structural formula highlights two methoxy groups (-OCH3) attached to a propane backbone. The compound is a colorless liquid with a pleasant odor, making it suitable for various chemical reactions and formulations.

Recent studies have focused on the synthesis pathways of 1,2-dimethoxypropane, exploring novel methods to enhance its production efficiency. Researchers have reported that the compound can be synthesized via the oxidation of diols or through the reaction of alcohols with alkyl halides in the presence of a strong base. These advancements have not only improved yield but also reduced the environmental footprint of its production processes.

The physical properties of 1,2-dimethoxypropane are well-documented, with a boiling point of approximately 69°C and a density of 0.94 g/cm3. Its low viscosity and high solubility in organic solvents make it an ideal solvent for various industrial applications. Recent research has also highlighted its role as a green solvent, particularly in the pharmaceutical and agrochemical industries, where it is used to dissolve active ingredients without leaving harmful residues.

In terms of application, 1,2-dimethoxypropane has found extensive use in the synthesis of fine chemicals, such as flavorants, fragrances, and pharmaceutical intermediates. Its ability to act as a phase transfer catalyst has been a focal point in recent studies, where it facilitates reactions between immiscible phases, thereby improving reaction efficiency and selectivity. This property has made it invaluable in processes like nucleophilic substitutions and esterifications.

The environmental impact of 1,2-dimethoxypropane has also been a subject of recent research. Studies indicate that it is biodegradable under aerobic conditions, with complete degradation occurring within 28 days. This makes it a safer alternative to traditional solvents that persist longer in the environment. Additionally, its low toxicity profile has been confirmed through acute toxicity tests, further supporting its use in eco-friendly applications.

Looking ahead, ongoing research is exploring the potential of 1,2-dimethoxypropane as a building block for advanced materials such as polymers and surfactants. Its unique combination of ether linkages and alkyl chains offers opportunities for creating materials with tailored properties for specific applications.

In conclusion, 1,2-dimethoxypropane (CAS No. 7778-85-0) stands out as a critical compound in modern organic chemistry due to its versatility and eco-friendly properties. With continuous advancements in synthesis techniques and application development, this compound is poised to play an even more significant role in shaping future chemical innovations.

7778-85-0 (1,2-dimethoxypropane) Related Products

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Suzhou Senfeida Chemical Co., Ltd
(CAS:7778-85-0)1,2-Dimethoxypropane
sfd8170
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:7778-85-0)丙二醇二甲醚
LE26448362
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
Email