Cas no 77510-50-0 ((3R)-3-hydroxypyrrolidin-2-one)
(3R)-3-Hydroxypyrrolidin-2-one is a chiral lactam derivative characterized by a hydroxyl group at the 3-position of the pyrrolidin-2-one ring. This compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and bioactive molecules. Its stereochemistry makes it valuable for asymmetric synthesis, enabling the construction of enantiomerically pure compounds. The hydroxyl group offers a reactive site for further functionalization, facilitating derivatization into more complex structures. Additionally, its lactam core is stable under a range of reaction conditions, making it suitable for multi-step synthetic routes. This compound is often employed in the development of enzyme inhibitors, peptidomimetics, and other biologically active agents.
77510-50-0 structure
Product Name:(3R)-3-hydroxypyrrolidin-2-one
CAS No:77510-50-0
MF:C4H7NO2
MW:101.103881120682
MDL:MFCD12911759
CID:829842
PubChem ID:641547
Update Time:2025-06-06
(3R)-3-hydroxypyrrolidin-2-one Chemical and Physical Properties
Names and Identifiers
-
- (R)-3-Hydroxypyrrolidin-2-one
- (R)- 3-HYDROXY-2-PYRROLIDINONE
- (R)-3-Hydroxy-2-pyrrolidone
- (3R)-3-hydroxy-2-pyrrolidinone
- (R)-(+)-3-hydroxy-2-pyrrolidinone
- (R)-4-hydroxy-2-oxopyrrolidine
- 2-pyrrolidinone,3-hydroxy
- (3R)-3-hydroxypyrrolidin-2-one
- 2-Oxopyrrolidine-3alpha-ol
- (R)-3-hydroxy-pyrrolidin-2-one
- FRKGSNOMLIYPSH-GSVOUGTGSA-N
- RKL10137
- CH0019
- FCH951513
- RP18726
- AB0026687
- AX8162579
- W84
- SCHEMBL321868
- DTXSID50348929
- CS-W018663
- DS-13015
- AKOS016842412
- 77510-50-0
- AMY14450
- Q-103494
- EN300-93559
- MFCD12911759
- DB-002195
-
- MDL： MFCD12911759
- Inchi： 1S/C4H7NO2/c6-3-1-2-5-4(3)7/h3,6H,1-2H2,(H,5,7)/t3-/m1/s1
- InChI Key： FRKGSNOMLIYPSH-GSVOUGTGSA-N
- SMILES： O[C@H]1C(NCC1)=O
Computed Properties
- Exact Mass: 101.04800
- Monoisotopic Mass: 101.047678466g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 7
- Rotatable Bond Count: 0
- Complexity: 91.7
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 49.3
- XLogP3: -0.9
Experimental Properties
- Density: 1.292
- Melting Point: 100-103 oC
- Boiling Point: 364 oC
- Flash Point: 174 oC
- Refractive Index: 1.513
- PSA: 49.33000
- LogP: -0.80400
(3R)-3-hydroxypyrrolidin-2-one Security Information
- Hazard Statement： H302-H315-H319-H332-H335
- Storage Condition：Sealed in dry,2-8°C
(3R)-3-hydroxypyrrolidin-2-one Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A109006241-1g |
(R)-3-Hydroxypyrrolidin-2-one |
77510-50-0 | 97% | 1g |
$317.79 | 2023-09-01 | |
| Alichem | A109006241-5g |
(R)-3-Hydroxypyrrolidin-2-one |
77510-50-0 | 97% | 5g |
$943.40 | 2023-09-01 | |
| Alichem | A109006241-10g |
(R)-3-Hydroxypyrrolidin-2-one |
77510-50-0 | 97% | 10g |
$1262.50 | 2023-09-01 | |
| Fluorochem | 092249-250mg |
R)-3-Hydroxypyrrolidin-2-one |
77510-50-0 | 95% | 250mg |
￡57.00 | 2022-03-01 | |
| Fluorochem | 092249-1g |
R)-3-Hydroxypyrrolidin-2-one |
77510-50-0 | 95% | 1g |
￡156.00 | 2022-03-01 | |
| Fluorochem | 092249-5g |
R)-3-Hydroxypyrrolidin-2-one |
77510-50-0 | 95% | 5g |
￡476.00 | 2022-03-01 | |
| Fluorochem | 092249-10g |
R)-3-Hydroxypyrrolidin-2-one |
77510-50-0 | 95% | 10g |
￡798.00 | 2022-03-01 | |
| ChemScence | CS-W018663-250mg |
(R)-3-Hydroxypyrrolidin-2-one |
77510-50-0 | ≥97.0% | 250mg |
$59.0 | 2022-04-26 | |
| ChemScence | CS-W018663-1g |
(R)-3-Hydroxypyrrolidin-2-one |
77510-50-0 | ≥97.0% | 1g |
$139.0 | 2022-04-26 | |
| ChemScence | CS-W018663-5g |
(R)-3-Hydroxypyrrolidin-2-one |
77510-50-0 | ≥97.0% | 5g |
$458.0 | 2022-04-26 |
(3R)-3-hydroxypyrrolidin-2-one Suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:77510-50-0)(R)-3-Hydroxypyrrolidin-2-one
Order Number:sfd11609
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:35
Price ($):discuss personally
Email:[email protected]
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:77510-50-0)(3R)-3-hydroxypyrrolidin-2-one
Order Number:A847787
Stock Status:in Stock
Quantity:5g/25g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 07:16
Price ($):289.0/1012.0
Email:[email protected]
(3R)-3-hydroxypyrrolidin-2-one Related Literature
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Christopher J. Harrison,Kyle J. Berean,Enrico Della Gaspera,Jian Zhen Ou,Richard B. Kaner,Kourosh Kalantar-zadeh,Torben Daeneke Nanoscale, 2016,8, 16276-16283
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Christopher B. Rodell,Christopher B. Highley,Minna H. Chen,Neville N. Dusaj,Chao Wang,Lin Han,Jason A. Burdick Soft Matter, 2016,12, 7839-7847
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Bo Chen,Xiaotong Shen,Zhangfeng Luo,Di Cai,Changjing Chen,Changwei Zhang,Peiyong Qin,Hui Cao,Tianwei Tan RSC Adv., 2018,8, 25602-25610
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Lianqin Wang,Rachida Bance-Soualhi,Julia Ponce-González,Pilar Ocón,Edson A. Ticianelli,Daniel K. Whelligan,John R. Varcoe J. Mater. Chem. A, 2018,6, 24330-24341
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