Cas no 760934-24-5 (2-Isopropylamino-thiazole-4-carboxylic acid)

2-Isopropylamino-thiazole-4-carboxylic acid is a thiazole-based carboxylic acid derivative featuring an isopropylamino substituent at the 2-position. This compound is of interest in organic synthesis and pharmaceutical research due to its versatile reactivity, particularly as a building block for heterocyclic compounds. The thiazole core contributes to its potential biological activity, while the carboxylic acid group enables further functionalization through amidation, esterification, or other derivatization reactions. Its structural features make it a valuable intermediate in the development of agrochemicals, pharmaceuticals, and specialty chemicals. The isopropylamino moiety may influence solubility and steric properties, offering tunability for targeted applications. Proper handling and storage are recommended to maintain stability.
2-Isopropylamino-thiazole-4-carboxylic acid structure
760934-24-5 structure
Product Name:2-Isopropylamino-thiazole-4-carboxylic acid
CAS No:760934-24-5
MF:C7H10N2O2S
MW:186.231500148773
MDL:MFCD06795891
CID:2133959
PubChem ID:11953490
Update Time:2025-05-24

2-Isopropylamino-thiazole-4-carboxylic acid Chemical and Physical Properties

Names and Identifiers

    • 2-[(1-methylethyl)amino]-4-Thiazolecarboxylic acid
    • 2-(propan-2-ylamino)-1,3-thiazole-4-carboxylic acid
    • 2-[(Propan-2-yl)amino]-1,3-thiazole-4-carboxylic acid
    • 2-(isopropylamino)-1,3-thiazole-4-carboxylic acid
    • 2-Isopropylamino-thiazole-4-carboxylic acid
    • 2-(isopropylamino)thiazole-4-carboxylic acid
    • SB17919
    • SCHEMBL2744060
    • DTXSID70474592
    • 760934-24-5
    • CS-0455450
    • F2158-1427
    • starbld0018571
    • EN300-238006
    • DB-075061
    • AKOS006292889
    • MDL: MFCD06795891
    • Inchi: 1S/C7H10N2O2S/c1-4(2)8-7-9-5(3-12-7)6(10)11/h3-4H,1-2H3,(H,8,9)(H,10,11)
    • InChI Key: HULGNRJQYKBQCC-UHFFFAOYSA-N
    • SMILES: S1C=C(C(=O)O)N=C1NC(C)C

Computed Properties

  • Exact Mass: 186.04629874g/mol
  • Monoisotopic Mass: 186.04629874g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 3
  • Complexity: 175
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 90.5
  • XLogP3: 1.9

2-Isopropylamino-thiazole-4-carboxylic acid Pricemore >>

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Additional information on 2-Isopropylamino-thiazole-4-carboxylic acid

2-Isopropylamino-thiazole-4-carboxylic Acid: A Comprehensive Overview

The compound with CAS No. 760934-24-5, known as 2-Isopropylamino-thiazole-4-carboxylic acid, is a significant molecule in the field of organic chemistry and pharmacology. This compound has garnered attention due to its unique structural properties and potential applications in drug development. The thiazole ring, a key structural component, contributes to its stability and reactivity, making it a valuable compound for researchers.

Recent studies have highlighted the antimicrobial and anti-inflammatory properties of 2-Isopropylamino-thiazole-4-carboxylic acid, positioning it as a promising candidate for therapeutic interventions. Researchers have explored its ability to inhibit bacterial growth and reduce inflammation, which are critical areas in modern medicine. The isopropylamino group attached to the thiazole ring plays a pivotal role in these activities by enhancing the molecule's bioavailability and interaction with target receptors.

The synthesis of 2-Isopropylamino-thiazole-4-carboxylic acid involves a multi-step process that combines traditional organic synthesis techniques with modern catalytic methods. The incorporation of the carboxylic acid group at the 4-position of the thiazole ring is crucial for its biological activity. Recent advancements in catalytic asymmetric synthesis have enabled the production of enantiomerically pure forms of this compound, which is essential for pharmacological studies.

In terms of applications, 2-Isopropylamino-thiazole-4-carboxylic acid has shown potential in the development of neuroprotective agents. Studies suggest that this compound can modulate neurotransmitter systems, offering a new avenue for treating neurodegenerative diseases such as Alzheimer's and Parkinson's. Its ability to cross the blood-brain barrier makes it particularly appealing for central nervous system-related therapies.

Moreover, the compound has been investigated for its role in anticancer therapy. Preclinical studies indicate that 2-Isopropylamino-thiazole-4-carboxylic acid can induce apoptosis in cancer cells while sparing healthy cells, which is a desirable trait for chemotherapeutic agents. The mechanism involves targeting specific signaling pathways that are overactive in cancer cells.

The environmental impact of synthesizing and using 2-Isopropylamino-thiazole-4-carboxylic acid has also been a topic of interest. Researchers are exploring green chemistry approaches to minimize waste and reduce the ecological footprint of its production. This includes the use of biodegradable catalysts and solvent systems that are compliant with sustainability goals.

In conclusion, 2-Isopropylamino-thiazole-4-carboxylic acid (CAS No. 760934-24-5) is a versatile compound with a wide range of applications in medicine and materials science. Its unique chemical structure, combined with recent advancements in synthesis and application research, positions it as a key molecule for future innovations in healthcare and beyond.

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