Cas no 760934-24-5 (2-Isopropylamino-thiazole-4-carboxylic acid)
2-Isopropylamino-thiazole-4-carboxylic acid Chemical and Physical Properties
Names and Identifiers
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- 2-[(1-methylethyl)amino]-4-Thiazolecarboxylic acid
- 2-(propan-2-ylamino)-1,3-thiazole-4-carboxylic acid
- 2-[(Propan-2-yl)amino]-1,3-thiazole-4-carboxylic acid
- 2-(isopropylamino)-1,3-thiazole-4-carboxylic acid
- 2-Isopropylamino-thiazole-4-carboxylic acid
- 2-(isopropylamino)thiazole-4-carboxylic acid
- SB17919
- SCHEMBL2744060
- DTXSID70474592
- 760934-24-5
- CS-0455450
- F2158-1427
- starbld0018571
- EN300-238006
- DB-075061
- AKOS006292889
-
- MDL: MFCD06795891
- Inchi: 1S/C7H10N2O2S/c1-4(2)8-7-9-5(3-12-7)6(10)11/h3-4H,1-2H3,(H,8,9)(H,10,11)
- InChI Key: HULGNRJQYKBQCC-UHFFFAOYSA-N
- SMILES: S1C=C(C(=O)O)N=C1NC(C)C
Computed Properties
- Exact Mass: 186.04629874g/mol
- Monoisotopic Mass: 186.04629874g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 12
- Rotatable Bond Count: 3
- Complexity: 175
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 90.5
- XLogP3: 1.9
2-Isopropylamino-thiazole-4-carboxylic acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | T705600-10mg |
2-[(propan-2-yl)amino]-1,3-thiazole-4-carboxylic acid |
760934-24-5 | 10mg |
$ 50.00 | 2022-06-02 | ||
| TRC | T705600-50mg |
2-[(propan-2-yl)amino]-1,3-thiazole-4-carboxylic acid |
760934-24-5 | 50mg |
$ 160.00 | 2022-06-02 | ||
| TRC | T705600-100mg |
2-[(propan-2-yl)amino]-1,3-thiazole-4-carboxylic acid |
760934-24-5 | 100mg |
$ 250.00 | 2022-06-02 | ||
| Enamine | EN300-238006-0.05g |
2-[(propan-2-yl)amino]-1,3-thiazole-4-carboxylic acid |
760934-24-5 | 95% | 0.05g |
$46.0 | 2024-06-19 | |
| Enamine | EN300-238006-0.1g |
2-[(propan-2-yl)amino]-1,3-thiazole-4-carboxylic acid |
760934-24-5 | 95% | 0.1g |
$73.0 | 2024-06-19 | |
| Enamine | EN300-238006-0.25g |
2-[(propan-2-yl)amino]-1,3-thiazole-4-carboxylic acid |
760934-24-5 | 95% | 0.25g |
$105.0 | 2024-06-19 | |
| Enamine | EN300-238006-0.5g |
2-[(propan-2-yl)amino]-1,3-thiazole-4-carboxylic acid |
760934-24-5 | 95% | 0.5g |
$197.0 | 2024-06-19 | |
| Enamine | EN300-238006-1.0g |
2-[(propan-2-yl)amino]-1,3-thiazole-4-carboxylic acid |
760934-24-5 | 95% | 1.0g |
$284.0 | 2024-06-19 | |
| Enamine | EN300-238006-2.5g |
2-[(propan-2-yl)amino]-1,3-thiazole-4-carboxylic acid |
760934-24-5 | 95% | 2.5g |
$558.0 | 2024-06-19 | |
| Enamine | EN300-238006-5.0g |
2-[(propan-2-yl)amino]-1,3-thiazole-4-carboxylic acid |
760934-24-5 | 95% | 5.0g |
$825.0 | 2024-06-19 |
2-Isopropylamino-thiazole-4-carboxylic acid Related Literature
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A. B. F. da Silva,K. Capelle Phys. Chem. Chem. Phys., 2009,11, 4564-4569
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2. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
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Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
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Manickam Bakthadoss,Tadiparthi Thirupathi Reddy,Vishal Agarwal,Duddu S. Sharada Chem. Commun., 2022,58, 1406-1409
Additional information on 2-Isopropylamino-thiazole-4-carboxylic acid
2-Isopropylamino-thiazole-4-carboxylic Acid: A Comprehensive Overview
The compound with CAS No. 760934-24-5, known as 2-Isopropylamino-thiazole-4-carboxylic acid, is a significant molecule in the field of organic chemistry and pharmacology. This compound has garnered attention due to its unique structural properties and potential applications in drug development. The thiazole ring, a key structural component, contributes to its stability and reactivity, making it a valuable compound for researchers.
Recent studies have highlighted the antimicrobial and anti-inflammatory properties of 2-Isopropylamino-thiazole-4-carboxylic acid, positioning it as a promising candidate for therapeutic interventions. Researchers have explored its ability to inhibit bacterial growth and reduce inflammation, which are critical areas in modern medicine. The isopropylamino group attached to the thiazole ring plays a pivotal role in these activities by enhancing the molecule's bioavailability and interaction with target receptors.
The synthesis of 2-Isopropylamino-thiazole-4-carboxylic acid involves a multi-step process that combines traditional organic synthesis techniques with modern catalytic methods. The incorporation of the carboxylic acid group at the 4-position of the thiazole ring is crucial for its biological activity. Recent advancements in catalytic asymmetric synthesis have enabled the production of enantiomerically pure forms of this compound, which is essential for pharmacological studies.
In terms of applications, 2-Isopropylamino-thiazole-4-carboxylic acid has shown potential in the development of neuroprotective agents. Studies suggest that this compound can modulate neurotransmitter systems, offering a new avenue for treating neurodegenerative diseases such as Alzheimer's and Parkinson's. Its ability to cross the blood-brain barrier makes it particularly appealing for central nervous system-related therapies.
Moreover, the compound has been investigated for its role in anticancer therapy. Preclinical studies indicate that 2-Isopropylamino-thiazole-4-carboxylic acid can induce apoptosis in cancer cells while sparing healthy cells, which is a desirable trait for chemotherapeutic agents. The mechanism involves targeting specific signaling pathways that are overactive in cancer cells.
The environmental impact of synthesizing and using 2-Isopropylamino-thiazole-4-carboxylic acid has also been a topic of interest. Researchers are exploring green chemistry approaches to minimize waste and reduce the ecological footprint of its production. This includes the use of biodegradable catalysts and solvent systems that are compliant with sustainability goals.
In conclusion, 2-Isopropylamino-thiazole-4-carboxylic acid (CAS No. 760934-24-5) is a versatile compound with a wide range of applications in medicine and materials science. Its unique chemical structure, combined with recent advancements in synthesis and application research, positions it as a key molecule for future innovations in healthcare and beyond.
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