• 1. Excitation dependent bidirectional electron transfer in phthalocyanine-functionalised MoS2 nanosheets?
  Christopher J. Harrison,Kyle J. Berean,Enrico Della Gaspera,Jian Zhen Ou,Richard B. Kaner,Kourosh Kalantar-zadeh,Torben Daeneke Nanoscale, 2016,8, 16276-16283
• 2. Evidence of rutile-to-anatase photo-induced electron transfer in mixed-phase TiO2 by solid-state NMR spectroscopy?
  Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
• 3. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
  XuxinCheng,XiaomingChen,PengyuanFan
• 4. Fate of Sb(v) and Sb(iii) species along a gradient of pH and oxygen concentration in the Carnoulès mine waters (Southern France)
  Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
• 5. Emerging investigator series: bacteriophages as nano engineering tools for quality monitoring and pathogen detection in water and wastewater
  Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Halobenzenes Fluorobenzenes

Comprehensive Guide to 1-Chloro-4-ethynyl-2-fluorobenzene (CAS No. 756895-72-4): Properties, Applications, and Industry Insights

1-Chloro-4-ethynyl-2-fluorobenzene (CAS No. 756895-72-4) is a specialized halogenated aromatic compound with a unique molecular structure, combining chloro, fluoro, and ethynyl functional groups. This compound has garnered significant attention in pharmaceutical intermediates and material science due to its versatile reactivity. Researchers frequently search for "synthesis of 1-Chloro-4-ethynyl-2-fluorobenzene" or "CAS 756895-72-4 applications," reflecting its growing relevance in synthetic chemistry.

The compound’s electron-withdrawing properties make it a valuable building block for cross-coupling reactions, particularly in Suzuki-Miyaura and Sonogashira couplings. Its fluorine substitution enhances metabolic stability, a critical factor in drug discovery—addressing common queries like "how to improve drug bioavailability." Recent studies highlight its role in designing PET radiotracers, aligning with the surge in interest around molecular imaging technologies.

From an industrial perspective, 1-Chloro-4-ethynyl-2-fluorobenzene is pivotal in developing liquid crystal materials and organic semiconductors. Searches for "high-performance OLED materials" often lead to derivatives of this compound, underscoring its utility in next-gen displays. Manufacturers prioritize its low toxicity profile, complying with green chemistry trends—a hot topic in "eco-friendly synthesis" discussions.

Analytical data for CAS No. 756895-72-4 reveals a melting point of 45–48°C and boiling point of 210–215°C, with solubility in common organic solvents like dichloromethane. These properties are frequently cited in "solvent selection guides" for fine chemical production. Stability under inert atmospheres ensures safe handling, though users often inquire about "storage conditions for halogenated benzenes."

Innovations in flow chemistry have streamlined the production of 1-Chloro-4-ethynyl-2-fluorobenzene, reducing waste and energy use—key concerns in "sustainable manufacturing" debates. Patent filings indicate its use in agrochemicals, particularly herbicide adjuvants, responding to searches for "crop protection chemicals."

In summary, CAS 756895-72-4 bridges multiple disciplines, from medicinal chemistry to advanced materials. Its adaptability to click chemistry protocols and alignment with Industry 4.0 automation trends position it as a compound of enduring scientific and commercial value.

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• 64583-18-2(BENZENE, 1-CHLORO-4-[(4-FLUOROPHENYL)ETHYNYL]-)
• 853782-94-2(BENZENE, 1-[(4-CHLOROPHENYL)ETHYNYL]-3-FLUORO-)
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• 1236120-19-6(3-Fluoro-4,4-dichlorobiphenyl)
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