Cas no 75024-22-5 (1,4-Dibromo-2,3-dimethylbenzene)

1,4-Dibromo-2,3-dimethylbenzene is a brominated aromatic compound characterized by its two bromine substituents at the 1 and 4 positions and methyl groups at the 2 and 3 positions on the benzene ring. This structure imparts high reactivity, making it a valuable intermediate in organic synthesis, particularly in cross-coupling reactions and the preparation of functionalized aromatic derivatives. Its symmetrical substitution pattern enhances regioselectivity in further chemical transformations. The compound is typically a solid at room temperature, with good stability under standard conditions. It is commonly used in pharmaceutical, agrochemical, and materials science research for constructing complex molecular frameworks. Proper handling is advised due to its halogenated nature.
1,4-Dibromo-2,3-dimethylbenzene structure
75024-22-5 structure
Product Name:1,4-Dibromo-2,3-dimethylbenzene
CAS No:75024-22-5
MF:C8H8Br2
MW:263.957120895386
MDL:MFCD06796460
CID:557788
PubChem ID:12100427
Update Time:2025-11-02

1,4-Dibromo-2,3-dimethylbenzene Chemical and Physical Properties

Names and Identifiers

    • 1,4-Dibromo-2,3-dimethylbenzene
    • Benzene,1,4-dibromo-2,3-dimethyl-
    • 3,6-Dibromo-o-xylene
    • dimethyl p-dibromobenzene
    • 3,6-dibromo-1,2-xylene
    • 1,4-DIBROMO-O-XYLENE
    • IVJJDBCZDJFMNZ-UHFFFAOYSA-N
    • FCH1328501
    • AS04140
    • BC005268
    • SY104427
    • AX8217729
    • AB0042932
    • BB 0262567
    • ST24036844
    • Z0828
    • AKOS016005800
    • FT-0769432
    • AMY28013
    • 75024-22-5
    • DTXSID80477574
    • CS-W019403
    • DS-14893
    • SCHEMBL1590024
    • MFCD06796460
    • DA-03096
    • MDL: MFCD06796460
    • Inchi: 1S/C8H8Br2/c1-5-6(2)8(10)4-3-7(5)9/h3-4H,1-2H3
    • InChI Key: IVJJDBCZDJFMNZ-UHFFFAOYSA-N
    • SMILES: BrC1=CC=C(C(C)=C1C)Br

Computed Properties

  • Exact Mass: 261.89900
  • Monoisotopic Mass: 261.899
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 0
  • Complexity: 99.8
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 0
  • XLogP3: 4

Experimental Properties

  • Density: 1.71
  • Melting Point: Not available
  • Boiling Point: 266.983°C at 760 mmHg
  • Flash Point: 129.171°C
  • Refractive Index: 1.579
  • PSA: 0.00000
  • LogP: 3.82840
  • Vapor Pressure: 0.0±0.5 mmHg at 25°C

1,4-Dibromo-2,3-dimethylbenzene Customs Data

  • HS CODE:2903999090
  • Customs Data:

    China Customs Code:

    2903999090

    Overview:

    2903999090 Other aromatic halogenated derivatives. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

1,4-Dibromo-2,3-dimethylbenzene Pricemore >>

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Additional information on 1,4-Dibromo-2,3-dimethylbenzene

1,4-Dibromo-2,3-dimethylbenzene (CAS No. 75024-22-5): Properties, Applications, and Market Insights

1,4-Dibromo-2,3-dimethylbenzene (CAS No. 75024-22-5) is a halogenated aromatic compound with significant industrial and research applications. This compound, also known as 2,3-dimethyl-1,4-dibromobenzene, belongs to the class of dibrominated dimethylbenzenes, which are widely used in organic synthesis and material science. Its molecular formula is C8H8Br2, and it features two bromine atoms at the 1 and 4 positions, along with methyl groups at the 2 and 3 positions of the benzene ring.

The physical and chemical properties of 1,4-Dibromo-2,3-dimethylbenzene make it a valuable intermediate in various chemical processes. It typically appears as a white to off-white crystalline solid with a melting point ranging between 80-85°C. The compound is soluble in organic solvents such as ethanol, acetone, and dichloromethane but exhibits limited solubility in water. Its stability under standard conditions and reactivity toward nucleophilic substitution reactions make it a preferred choice for synthesizing more complex organic molecules.

One of the primary applications of 1,4-Dibromo-2,3-dimethylbenzene is in the production of pharmaceutical intermediates. Researchers and manufacturers utilize this compound to develop active pharmaceutical ingredients (APIs) and other fine chemicals. Its role in Suzuki-Miyaura cross-coupling reactions, a popular method for forming carbon-carbon bonds, has garnered attention in recent years due to the growing demand for efficient synthetic routes in drug discovery.

In the field of material science, 1,4-Dibromo-2,3-dimethylbenzene serves as a building block for advanced polymers and liquid crystals. The compound's ability to undergo polymerization reactions makes it useful for creating high-performance materials with specific thermal and mechanical properties. Additionally, its incorporation into liquid crystal displays (LCDs) has been explored, aligning with the global trend toward sustainable and energy-efficient display technologies.

The market demand for 1,4-Dibromo-2,3-dimethylbenzene has seen steady growth, driven by its versatile applications. Recent trends indicate increased interest from the electronics industry, particularly in the development of organic semiconductors and conductive polymers. As the world shifts toward renewable energy and smart devices, the demand for specialized chemical intermediates like 2,3-dimethyl-1,4-dibromobenzene is expected to rise.

Environmental and safety considerations are paramount when handling 1,4-Dibromo-2,3-dimethylbenzene. While the compound is not classified as hazardous under standard regulations, proper storage and handling procedures should be followed to ensure workplace safety. It is recommended to store the material in a cool, dry place, away from direct sunlight and incompatible substances such as strong oxidizing agents.

For researchers and industry professionals seeking high-purity 1,4-Dibromo-2,3-dimethylbenzene, several suppliers offer the compound in various grades. Analytical techniques such as gas chromatography (GC) and nuclear magnetic resonance (NMR) spectroscopy are commonly employed to verify its purity and structural integrity. When purchasing this chemical, it is advisable to request certificates of analysis (CoA) to ensure compliance with specific application requirements.

The synthesis of 1,4-Dibromo-2,3-dimethylbenzene typically involves the bromination of 2,3-dimethylbenzene (o-xylene) using bromine or brominating agents under controlled conditions. Recent advancements in green chemistry have led to the development of more sustainable bromination methods, reducing the environmental impact of the production process. These innovations align with the broader industry focus on eco-friendly manufacturing practices.

In conclusion, 1,4-Dibromo-2,3-dimethylbenzene (CAS No. 75024-22-5) is a versatile chemical intermediate with wide-ranging applications in pharmaceuticals, materials science, and electronics. Its unique properties and reactivity make it an indispensable tool for researchers and manufacturers alike. As industries continue to evolve and embrace new technologies, the demand for specialized compounds like 2,3-dimethyl-1,4-dibromobenzene is poised to grow, driving further innovation in synthetic chemistry and material development.

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