Cas no 74592-36-2 (Ethyl 2-cyclopropylideneacetate)

Ethyl 2-cyclopropylideneacetate is a versatile cyclic ester compound characterized by its reactive cyclopropylidene and ester functional groups. This structure makes it a valuable intermediate in organic synthesis, particularly for constructing cyclopropane-containing frameworks, which are prevalent in pharmaceuticals and agrochemicals. Its high reactivity in cycloaddition and conjugate addition reactions enables efficient derivatization, facilitating the development of complex molecular architectures. The ethyl ester group enhances solubility in organic solvents, simplifying handling in synthetic workflows. This compound is particularly useful in medicinal chemistry for exploring structure-activity relationships due to its constrained ring system and modifiable functional groups. Proper storage under inert conditions is recommended to maintain stability.
Ethyl 2-cyclopropylideneacetate structure
74592-36-2 structure
Product Name:Ethyl 2-cyclopropylideneacetate
CAS No:74592-36-2
MF:C7H10O2
MW:126.153102397919
MDL:MFCD08460630
CID:562480
PubChem ID:11040705
Update Time:2025-05-20

Ethyl 2-cyclopropylideneacetate Chemical and Physical Properties

Names and Identifiers

    • Ethyl 2-cyclopropylideneacetate
    • 2-cyclopropylideneAcetic acid ethyl ester
    • Aceticacid, 2-cyclopropylidene-, ethyl ester
    • ETHYL 2-CYCLOPROPYLIDENEPROPANOATE
    • Aceticacid, cyclopropylidene-, ethyl ester (9CI)
    • Cyclopropylideneacetic acid ethylester
    • Ethyl cyclopropylideneacetate
    • Cyclopropylidene-acetic acid ethyl ester
    • AS-43917
    • Ethyl2-cyclopropylideneacetate
    • DTXSID10452879
    • SCHEMBL2502784
    • AMY37969
    • SY147547
    • SB38545
    • A936476
    • EN300-105471
    • 74592-36-2
    • Cyclopropyludene-Acetic Acid Ethyl Ester
    • MFCD08460630
    • AKOS006291478
    • CS-0340229
    • CINXGNHRKLMYRK-UHFFFAOYSA-N
    • FT-0737459
    • F2147-3516
    • ETHYL 2-[(1E)-CYCLOPROPYLIDENE]ACETATE
    • DB-074853
    • MDL: MFCD08460630
    • Inchi: 1S/C7H10O2/c1-2-9-7(8)5-6-3-4-6/h5H,2-4H2,1H3
    • InChI Key: CINXGNHRKLMYRK-UHFFFAOYSA-N
    • SMILES: O(CC)C(/C=C1/CC/1)=O

Computed Properties

  • Exact Mass: 126.068079557g/mol
  • Monoisotopic Mass: 126.068079557g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 3
  • Complexity: 141
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.9
  • Topological Polar Surface Area: 26.3?2

Experimental Properties

  • Density: 1.179±0.06 g/cm3 (20 oC 760 Torr),
  • Boiling Point: 78-82 oC (1 Torr)
  • Flash Point: 74.1±9.9 oC,
  • Solubility: Slightly soluble (2.8 g/l) (25 o C),
  • PSA: 26.30000
  • LogP: 1.26970

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Ethyl 2-cyclopropylideneacetate Suppliers

Amadis Chemical Company Limited
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(CAS:74592-36-2)Ethyl 2-cyclopropylideneacetate
Order Number:A936476
Stock Status:in Stock
Quantity:1g/5g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 15:20
Price ($):257.0/901.0

Additional information on Ethyl 2-cyclopropylideneacetate

Ethyl 2-Cyclopropylideneacetate: A Comprehensive Overview

Ethyl 2-cyclopropylideneacetate, with CAS No. 74592-36-2, is a versatile organic compound that has garnered significant attention in the fields of organic synthesis and materials science. This compound, characterized by its unique structure featuring a cyclopropane ring fused to an acetyl group, has been extensively studied for its potential applications in various industries. In recent years, advancements in synthetic methodologies and the exploration of its properties have further highlighted its importance in modern chemistry.

The cyclopropylidene moiety in Ethyl 2-cyclopropylideneacetate is a key structural feature that contributes to its reactivity and stability. This three-membered ring system is known for its high strain energy, which makes it a valuable component in the synthesis of complex molecules. Researchers have demonstrated that this compound can serve as an efficient precursor for the construction of bioactive compounds, including pharmaceutical agents and agrochemicals. Its ability to undergo various transformations, such as ring-opening reactions and conjugate additions, has made it a valuable tool in organic synthesis.

Recent studies have focused on the synthesis and characterization of Ethyl 2-cyclopropylideneacetate, particularly in the context of green chemistry. Scientists have developed more sustainable methods for its production, including the use of catalytic systems that minimize waste and reduce environmental impact. These advancements not only enhance the efficiency of the synthesis process but also align with global efforts to promote eco-friendly chemical practices.

In terms of applications, Ethyl 2-cyclopropylideneacetate has been utilized in the development of novel materials with unique properties. For instance, its incorporation into polymer systems has been shown to improve mechanical strength and thermal stability. Additionally, this compound has been explored as a building block for the creation of advanced materials used in electronics and optoelectronics.

One of the most promising areas of research involving Ethyl 2-cyclopropylideneacetate is its role in drug discovery. The compound's ability to act as an intermediate in the synthesis of bioactive molecules has led to its use in the development of potential therapeutic agents. Recent findings suggest that derivatives of this compound may exhibit anti-inflammatory and antioxidant properties, making them candidates for further investigation in pharmacological studies.

The cyclopropane ring in Ethyl 2-cyclopropylideneacetate also plays a crucial role in its reactivity under various reaction conditions. For example, studies have shown that this compound can undergo [2+1] cycloaddition reactions with alkenes and alkynes, providing a straightforward route to complex cyclic structures. Such reactions are not only efficient but also offer excellent control over stereochemistry, making them highly valuable in organic synthesis.

Furthermore, Ethyl 2-cyclopropylideneacetate has been employed as a catalyst or ligand in transition metal-mediated reactions. Its ability to coordinate with metal centers enhances the catalytic activity of these systems, leading to improved yields and selectivity. This property has been exploited in various industrial processes, including olefin polymerization and cross-coupling reactions.

In conclusion, Ethyl 2-cyclopropylideneacetate (CAS No. 74592-36-2) is a multifaceted compound with a wide range of applications across different scientific disciplines. Its unique structure and reactivity make it an invaluable tool in organic synthesis, materials science, and drug discovery. As research continues to uncover new aspects of this compound's potential, it is expected to play an even more significant role in advancing modern chemistry.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:74592-36-2)Ethyl 2-cyclopropylideneacetate
A936476
Purity:99%/99%
Quantity:1g/5g
Price ($):257.0/901.0
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