Cas no 745784-12-7 (Quinolin-2-ylboronic acid)
Quinolin-2-ylboronic acid Chemical and Physical Properties
Names and Identifiers
-
- Quinolin-2-ylboronic acid
- Quinoline-2-boronic acid
- quinolin-2-yl-2-boronic acid
- 2-Quinoline boronic acid
- 2-Quinolinylboronic acid
- 745784-12-7
- quinolineboronic
- FT-0603702
- SCHEMBL27924
- MFCD03095375
- 2-quinolinyl-boronic acid
- A838164
- AC-22330
- (quinolin-2-yl)boronic acid
- J-510323
- CS-0175272
- AKOS005259699
- GS-6154
- DWHCQRBWSBKHMI-UHFFFAOYSA-N
- 2-Quinolinylboronic acid;Quinoline-2-boronic acid
- EN300-212536
- AMY10983
- AB13731
- quinoline boronic acid
- Quinolin-2-ylboronicacid
- A9548
- DTXSID70623225
- 4-(4-CARBOXYPHENYL)PIPERIDINEHCL
- F16122
- DB-032269
- 800-408-6
-
- MDL: MFCD03095375
- Inchi: 1S/C9H8BNO2/c12-10(13)9-6-5-7-3-1-2-4-8(7)11-9/h1-6,12-13H
- InChI Key: DWHCQRBWSBKHMI-UHFFFAOYSA-N
- SMILES: OB(C1=CC=C2C=CC=CC2=N1)O
Computed Properties
- Exact Mass: 173.06500
- Monoisotopic Mass: 173.065
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 13
- Rotatable Bond Count: 1
- Complexity: 177
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 53.4A^2
Experimental Properties
- Color/Form: No data avaiable
- Density: 1.3±0.1 g/cm3
- Melting Point: >300 C
- Boiling Point: 400.3±37.0 °C at 760 mmHg
- Flash Point: 195.9±26.5 °C
- Refractive Index: 1.645
- PSA: 53.35000
- LogP: -0.08540
- Vapor Pressure: 0.0±1.0 mmHg at 25°C
Quinolin-2-ylboronic acid Security Information
- Signal Word:Warning
- Hazard Statement: H315; H319; H335
- Warning Statement: P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501
- Hazard Category Code: R36/37/38: irritating to eyes, respiratory tract and skin
- Safety Instruction: S26-S36
-
Hazardous Material Identification:
- Storage Condition:Store long-term at -20°C
- Safety Term:S26;S36
- Risk Phrases:R36/37/38
Quinolin-2-ylboronic acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | Q822189-250mg |
2-Quinolinylboronic acid |
745784-12-7 | 95% | 250mg |
¥4,680.00 | 2022-08-31 | |
| Apollo Scientific | OR8861-1g |
Quinoline-2-boronic acid |
745784-12-7 | 1g |
£334.00 | 2025-02-20 | ||
| abcr | AB246613-250 mg |
Quinoline-2-boronic acid, 95%; . |
745784-12-7 | 95% | 250mg |
€297.00 | 2023-04-27 | |
| abcr | AB246613-1 g |
Quinoline-2-boronic acid, 95%; . |
745784-12-7 | 95% | 1g |
€637.00 | 2023-04-27 | |
| TRC | Q701050-10mg |
Quinoline-2-boronic Acid |
745784-12-7 | 10mg |
$ 50.00 | 2022-06-03 | ||
| TRC | Q701050-50mg |
Quinoline-2-boronic Acid |
745784-12-7 | 50mg |
$ 95.00 | 2022-06-03 | ||
| TRC | Q701050-100mg |
Quinoline-2-boronic Acid |
745784-12-7 | 100mg |
$ 160.00 | 2022-06-03 | ||
| abcr | AB246613-250mg |
Quinoline-2-boronic acid, 95%; . |
745784-12-7 | 95% | 250mg |
€297.00 | 2025-04-16 | |
| abcr | AB246613-1g |
Quinoline-2-boronic acid, 95%; . |
745784-12-7 | 95% | 1g |
€637.00 | 2025-04-16 | |
| Chemenu | CM128384-1g |
quinolin-2-ylboronic acid |
745784-12-7 | 97% | 1g |
$*** | 2023-05-29 |
Quinolin-2-ylboronic acid Related Literature
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Helga Garcia,Rui Ferreira,Marija Petkovic,Jamie L. Ferguson,Maria C. Leit?o,H. Q. Nimal Gunaratne,Luís Paulo N. Rebelo Green Chem., 2010,12, 367-369
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Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
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J. Matthew Kurley,Phillip W. Halstenberg,Abbey McAlister,Stephen Raiman,Richard T. Mayes RSC Adv., 2019,9, 25602-25608
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Thi Thu Tram Nguyen,Thanh Binh Nguyen Org. Biomol. Chem., 2021,19, 6015-6020
Related Categories
- Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Quinolines and derivatives Quinolines and derivatives
- Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Quinolines and derivatives
- Other Chemical Reagents Derivatization Reagents
- Solvents and Organic Chemicals Organic Compounds Acids/Esters
Additional information on Quinolin-2-ylboronic acid
Quinolin-2-ylboronic Acid: A Comprehensive Overview
Quinolin-2-ylboronic acid (CAS No. 745784-12-7) is a versatile compound that has garnered significant attention in the fields of organic synthesis, materials science, and drug discovery. This compound, characterized by its quinoline skeleton with a boronic acid group at the 2-position, serves as a valuable building block in various chemical reactions. Its unique structure enables it to participate in cross-coupling reactions, making it an essential intermediate in the synthesis of complex molecules.
The synthesis of Quinolin-2-ylboronic acid has been optimized over the years, with researchers exploring various methodologies to enhance yield and efficiency. Recent studies have focused on catalytic systems that facilitate the formation of this compound from quinoline derivatives. For instance, the use of palladium catalysts in Suzuki-Miyaura coupling reactions has proven to be highly effective for incorporating the boronic acid group into the quinoline framework. These advancements have not only streamlined the production process but also opened new avenues for its application in medicinal chemistry.
In terms of applications, Quinolin-2-ylboronic acid has found extensive use in the construction of heterocyclic compounds, which are crucial in drug design. Its ability to undergo cross-coupling reactions with aryl halides has made it a key player in the synthesis of biologically active molecules. Recent research highlights its role in developing potential anticancer agents, where the quinoline moiety contributes to bioactivity while the boronic acid group facilitates further functionalization.
Moreover, Quinolin-2-ylboronic acid has emerged as a valuable precursor in materials science. Its incorporation into conjugated systems has led to the development of novel materials with tailored electronic properties. For example, researchers have utilized this compound to synthesize advanced organic semiconductors, which exhibit improved charge transport characteristics. These materials hold promise for applications in flexible electronics and optoelectronic devices.
The latest studies on Quinolin-2-ylboronic acid have delved into its catalytic properties. Scientists have discovered that this compound can act as a ligand in transition metal-catalyzed reactions, enhancing reaction efficiency and selectivity. This dual role as both a substrate and a catalyst underscores its versatility and positions it as a multi-functional tool in modern organic synthesis.
In conclusion, Quinolin-2-ylboronic acid (CAS No. 745784-12-7) stands out as a pivotal compound in contemporary chemical research. Its structural features and reactivity make it indispensable for constructing complex molecules and advanced materials. As ongoing research continues to uncover new applications and optimize its synthesis, this compound is poised to play an even greater role in shaping future innovations across diverse scientific disciplines.
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