• 1. An approach to biodegradable star polymeric architectures using disulfide coupling?
  Jingquan Liu,Huiyun Liu,Zhongfan Jia,Volga Bulmus,Thomas P. Davis Chem. Commun., 2008, 6582-6584
• 2. Acenaphthenic hopanoids, a novel series of aromatised
  Teresita Carrillo-Hernández,Philippe Schaeffer,Pierre Albrecht Chem. Commun., 2001, 1976-1977
• 3. An anti-ultrasonic-stripping effect in confined micro/nanoscale cavities and its applications for efficient multiscale metallic patterning?
  Quan Xiang,Yiqin Chen,Zhiqin Li,Kaixi Bi,Guanhua Zhang,Huigao Duan Nanoscale, 2016,8, 19541-19550
• 4. An amphoteric reactivity of a mixed-valent bis(μ-oxo)dimanganese(iii,iv) complex acting as an electrophile and a nucleophile?
  Muniyandi Sankaralingam,So Hyun Jeon,Yong-Min Lee,Mi Sook Seo,Wonwoo Nam Dalton Trans., 2016,45, 376-383
• 5. An artificial enzyme cascade amplification strategy for highly sensitive and specific detection of breast cancer-derived exosomes?
  Huiying Xu,Lu Zheng,Yu Zhou,Bang-Ce Ye Analyst, 2021,146, 5542-5549

2-Bromo-4-methoxybenzoic Acid (CAS No. 74317-85-4): A Comprehensive Overview

2-Bromo-4-methoxybenzoic acid (CAS No. 74317-85-4) is a versatile organic compound that has garnered significant attention in the fields of organic synthesis, medicinal chemistry, and pharmaceutical research. This compound is characterized by its unique structural features, which include a bromine atom and a methoxy group attached to a benzoic acid framework. These functional groups contribute to its diverse chemical properties and potential applications in various scientific and industrial contexts.

The chemical structure of 2-Bromo-4-methoxybenzoic acid can be represented as C₈H₇BrO₃. The presence of the bromine atom and the methoxy group imparts specific reactivity and solubility properties, making it a valuable intermediate in the synthesis of more complex molecules. The compound's ability to undergo various chemical transformations, such as substitution reactions, coupling reactions, and esterification, has made it an essential building block in organic synthesis.

In the realm of medicinal chemistry, 2-Bromo-4-methoxybenzoic acid has been explored for its potential therapeutic applications. Recent studies have highlighted its role as a precursor in the development of novel drugs targeting various diseases. For instance, researchers have utilized this compound to synthesize derivatives with enhanced biological activities, such as anti-inflammatory, antimicrobial, and anticancer properties. The methoxy group on the benzene ring can modulate the lipophilicity and bioavailability of the resulting compounds, which is crucial for optimizing their pharmacological profiles.

The synthetic versatility of 2-Bromo-4-methoxybenzoic acid has also been leveraged in the development of new materials. In polymer science, this compound can serve as a monomer or functionalized side chain in the synthesis of advanced polymers with tailored properties. These polymers have found applications in areas such as drug delivery systems, coatings, and electronic materials. The bromine atom can be used as a handle for post-polymerization modifications, allowing for the creation of multifunctional materials with enhanced performance characteristics.

In addition to its synthetic utility, 2-Bromo-4-methoxybenzoic acid has been studied for its environmental impact and biodegradability. Recent research has focused on understanding its fate and behavior in aquatic systems. Studies have shown that this compound can be biodegraded by certain microorganisms under aerobic conditions, which is an important consideration for its safe use in industrial processes and environmental applications.

The safety profile of 2-Bromo-4-methoxybenzoic acid is another critical aspect that has been extensively investigated. Toxicological studies have demonstrated that this compound exhibits low toxicity when handled properly. However, it is important to follow standard safety protocols during handling and storage to ensure worker safety and environmental protection. Proper personal protective equipment (PPE) should be used when working with this compound to minimize exposure risks.

In conclusion, 2-Bromo-4-methoxybenzoic acid (CAS No. 74317-85-4) is a multifaceted compound with a wide range of applications in organic synthesis, medicinal chemistry, and materials science. Its unique structural features and chemical properties make it an invaluable tool for researchers and scientists working in these fields. Ongoing research continues to uncover new possibilities for its use in developing innovative solutions to pressing scientific challenges.

• 121936-68-3(2-Bromo-5-hydroxy-4-methoxybenzoic acid)
• 17100-65-1(Methyl 2-Bromo-4-methoxybenzoate)
• 174417-54-0(2-Bromo-5-methoxy-3-methylbenzoic acid)
• 22921-68-2(2-Bromo-5-methoxybenzoic acid)
• 190965-43-6(2-Bromo-5-propoxybenzoic acid)
• 765944-34-1(Benzoic acid, 2-bromo-5-ethoxy-, methyl ester)
• 90050-65-0(2-bromo-4-hydroxy-5-methoxybenzoic acid)
• 74517-85-4(2-Bromo-4-methoxybenzoic acid)
• 31786-45-5(2-Bromo-6-methoxybenzoic acid)
• 6286-46-0(2-Bromo-4,5-dimethoxybenzoic acid)