Cas no 74209-50-0 (1-Pyridin-2-yl-ethanone oxime tosylate)

1-Pyridin-2-yl-ethanone oxime tosylate is a specialized organic compound featuring a pyridine core functionalized with an oxime tosylate group. This structure makes it a valuable intermediate in synthetic chemistry, particularly for the preparation of heterocyclic compounds and pharmaceuticals. The tosylate moiety enhances reactivity, facilitating nucleophilic substitution reactions, while the oxime group offers versatility in further derivatization. Its well-defined crystalline form ensures consistent purity and handling stability, making it suitable for precise laboratory applications. The compound’s compatibility with a range of reaction conditions underscores its utility in medicinal chemistry and materials science research. Proper storage under anhydrous conditions is recommended to maintain its integrity.
1-Pyridin-2-yl-ethanone oxime tosylate structure
74209-50-0 structure
Product Name:1-Pyridin-2-yl-ethanone oxime tosylate
CAS No:74209-50-0
MF:C14H14N2O3S
MW:290.337562084198
MDL:MFCD08056168
CID:555846
Update Time:2025-05-20

1-Pyridin-2-yl-ethanone oxime tosylate Chemical and Physical Properties

Names and Identifiers

    • Ethanone,1-(2-pyridinyl)-, O-[(4-methylphenyl)sulfonyl]oxime
    • 1-PYRIDIN-2-YL-ETHANONE OXIME TOSYLATE
    • 1-[2]Pyridyl-2-[4]pyridyl-aethan
    • 1-[2]pyridyl-2-[4]pyridyl-ethane
    • 1-[2]Pyridyl-aethanon-[O-(toluol-4-sulfonyl)-oxim]
    • 1-[2]pyridyl-ethanone-[O-(toluene-4-sulfonyl)-oxime ]
    • 1-<Pyridyl-(2)>-2-<pyridyl-(4)>-aethan
    • 2,4'-ethane-1,2-diyl-bis-pyridine
    • 2-[2-(pyridin-4-yl)ethyl]pyridine
    • (E)-[1-(pyridin-2-yl)ethylidene]amino 4-methylbenzene-1-sulfonate
    • Ethanone, 1-(2-pyridinyl)-, O-[(4-methylphenyl)sulfonyl]oxime
    • 1-Pyridin-2-yl-ethanone oxime tosylate
    • MDL： MFCD08056168
    • Inchi： 1S/C14H14N2O3S/c1-11-6-8-13(9-7-11)20(17,18)19-16-12(2)14-5-3-4-10-15-14/h3-10H,1-2H3
    • InChI Key： APEWFPWGCBGLFM-UHFFFAOYSA-N
    • SMILES： C(=NOS(C1=CC=C(C)C=C1)(=O)=O)(C1=NC=CC=C1)C

Computed Properties

  • Exact Mass: 290.07300

Experimental Properties

  • Density: 1.23±0.1 g/cm3(Predicted)
  • Boiling Point: 441.9±47.0 °C(Predicted)
  • PSA: 77.00000
  • LogP: 3.60030
  • pka: 1.19±0.19(Predicted)

1-Pyridin-2-yl-ethanone oxime tosylate Customs Data

  • HS CODE：2933399090
  • Customs Data：

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1-Pyridin-2-yl-ethanone oxime tosylate Pricemore >>

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P191205-500mg
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abcr
AB424610-10g
1-(2-Pyridinyl)ethanone O-[(4-methylphenyl)sulfonyl]oxime; .
 74209-50-0
10g
 €1759.20 2025-04-16
abcr
AB424610-1 g
1-(2-Pyridinyl)ethanone O-[(4-methylphenyl)sulfonyl]oxime; .
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 €694.20 2023-04-24
A2B Chem LLC
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Ethanone,1-(2-pyridinyl)-, O-[(4-methylphenyl)sulfonyl]oxime
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Ethanone,1-(2-pyridinyl)-, O-[(4-methylphenyl)sulfonyl]oxime
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A2B Chem LLC
AC62729-5g
Ethanone,1-(2-pyridinyl)-, O-[(4-methylphenyl)sulfonyl]oxime
 74209-50-0 95+%
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A2B Chem LLC
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Ethanone,1-(2-pyridinyl)-, O-[(4-methylphenyl)sulfonyl]oxime
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1-Pyridin-2-yl-ethanone oxime tosylate Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:74209-50-0)1-Pyridin-2-yl-ethanone oxime tosylate
Order Number:A1173495
Stock Status:in Stock
Quantity:1g/5g/10g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 01:25
Price ($):411.0/824.0/1042.0

1-Pyridin-2-yl-ethanone oxime tosylate Related Literature

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Additional information on 1-Pyridin-2-yl-ethanone oxime tosylate

Recent Advances in the Study of 1-Pyridin-2-yl-ethanone Oxime Tosylate (CAS: 74209-50-0)

The compound 1-Pyridin-2-yl-ethanone oxime tosylate (CAS: 74209-50-0) has recently garnered significant attention in the field of chemical biology and medicinal chemistry due to its potential applications in drug discovery and development. This research briefing aims to provide an overview of the latest findings related to this compound, focusing on its synthesis, biological activity, and potential therapeutic uses.

Recent studies have highlighted the role of 1-Pyridin-2-yl-ethanone oxime tosylate as a versatile intermediate in the synthesis of novel bioactive molecules. Researchers have successfully employed this compound in the development of inhibitors targeting key enzymes involved in inflammatory and oncogenic pathways. The tosylate group, in particular, has been shown to enhance the compound's stability and bioavailability, making it a valuable scaffold for further chemical modifications.

In a 2023 study published in the Journal of Medicinal Chemistry, scientists demonstrated the efficacy of 1-Pyridin-2-yl-ethanone oxime tosylate derivatives as potent inhibitors of protein kinases. The study utilized a combination of molecular docking and in vitro assays to identify optimal structural modifications that improve binding affinity and selectivity. These findings open new avenues for the design of targeted therapies for diseases such as cancer and autoimmune disorders.

Another significant advancement involves the application of this compound in the field of antimicrobial research. A recent report in Bioorganic & Medicinal Chemistry Letters detailed the synthesis of novel oxime derivatives using 1-Pyridin-2-yl-ethanone oxime tosylate as a starting material. These derivatives exhibited promising activity against drug-resistant bacterial strains, suggesting potential for development as next-generation antibiotics.

Despite these promising developments, challenges remain in optimizing the pharmacokinetic properties of 1-Pyridin-2-yl-ethanone oxime tosylate-based compounds. Ongoing research is focused on improving solubility and reducing off-target effects through structural optimization. Collaborative efforts between academic institutions and pharmaceutical companies are expected to accelerate the translation of these findings into clinical applications.

In conclusion, 1-Pyridin-2-yl-ethanone oxime tosylate (CAS: 74209-50-0) represents a valuable chemical entity with diverse applications in medicinal chemistry. The latest research underscores its potential as a scaffold for developing novel therapeutic agents, while also highlighting areas for further investigation. Continued exploration of this compound's chemical space is likely to yield significant contributions to drug discovery in the coming years.

74209-50-0 (1-Pyridin-2-yl-ethanone oxime tosylate) Related Products

Recommended suppliers
Amadis Chemical Company Limited
(CAS:74209-50-0)1-Pyridin-2-yl-ethanone oxime tosylate
A1173495
Purity:99%/99%/99%
Quantity:1g/5g/10g
Price ($):411.0/824.0/1042.0
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