Cas no 74079-00-8 (1,4-Dimethoxybenzene-d10)

1,4-Dimethoxybenzene-d10 is a deuterated analog of 1,4-dimethoxybenzene, where ten hydrogen atoms are replaced with deuterium. This isotopic labeling enhances its utility in NMR spectroscopy, providing sharper signals and reduced background interference for precise structural analysis. It is commonly employed as an internal standard or reference compound in quantitative NMR studies due to its high isotopic purity and chemical stability. The deuteration also minimizes proton exchange effects, improving reproducibility in kinetic and mechanistic investigations. Its compatibility with organic solvents and inertness under typical reaction conditions make it suitable for applications in pharmaceutical research, material science, and analytical chemistry.
1,4-Dimethoxybenzene-d10 structure
1,4-Dimethoxybenzene-d10 structure
Product Name:1,4-Dimethoxybenzene-d10
CAS No:74079-00-8
MF:C8H10O2
MW:148.225419521332
CID:555413
PubChem ID:90475750
Update Time:2025-05-20

1,4-Dimethoxybenzene-d10 Chemical and Physical Properties

Names and Identifiers

    • Benzene-1,2,4,5-d4,3,6-di(methoxy-d3)- (9CI)
    • p-Dimethoxybenzene-d10
    • 1,4-DIMETHOXYBENZENE-D10
    • HY-W015780S
    • CS-0564536
    • D99593
    • 1,2,4,5-tetradeuterio-3,6-bis(trideuteriomethoxy)benzene
    • 74079-00-8
    • 1,4-Dimethoxybenzene-d10
    • Inchi: 1S/C8H10O2/c1-9-7-3-5-8(10-2)6-4-7/h3-6H,1-2H3/i1D3,2D3,3D,4D,5D,6D
    • InChI Key: OHBQPCCCRFSCAX-ZGYYUIRESA-N
    • SMILES: O(C([2H])([2H])[2H])C1C([2H])=C([2H])C(=C([2H])C=1[2H])OC([2H])([2H])[2H]

Computed Properties

  • Exact Mass: 148.131
  • Monoisotopic Mass: 148.131
  • Isotope Atom Count: 10
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 2
  • Complexity: 73.3
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2
  • Topological Polar Surface Area: 18.5A^2

1,4-Dimethoxybenzene-d10 Pricemore >>

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Additional information on 1,4-Dimethoxybenzene-d10

1,4-Dimethoxybenzene-d10 (CAS No. 74079-00-8): An Overview of Its Properties, Applications, and Recent Research

1,4-Dimethoxybenzene-d10 (CAS No. 74079-00-8) is a deuterated derivative of 1,4-dimethoxybenzene, a compound widely used in various chemical and pharmaceutical applications. The deuterium atoms in this compound make it particularly useful in nuclear magnetic resonance (NMR) spectroscopy and other analytical techniques where the presence of deuterium can enhance the resolution and sensitivity of the analysis.

The chemical structure of 1,4-Dimethoxybenzene-d10 consists of a benzene ring with two methoxy groups (-OCH3) attached at the 1 and 4 positions, and all hydrogen atoms on the benzene ring and methoxy groups are replaced by deuterium atoms. This unique structure provides several advantages in research and industrial applications.

In recent years, the use of deuterated compounds has gained significant attention due to their enhanced stability and reduced metabolic degradation. This makes them particularly valuable in the development of pharmaceuticals, where they can improve the pharmacokinetic properties of drugs. For instance, a study published in the Journal of Medicinal Chemistry highlighted the use of deuterated analogs in drug design to enhance the half-life and efficacy of certain therapeutic agents.

1,4-Dimethoxybenzene-d10 is also an important intermediate in the synthesis of various organic compounds. Its stability and reactivity make it a versatile building block in organic synthesis. Researchers at the University of California, Berkeley, have utilized this compound in the development of novel catalysts for C-H activation reactions, which are crucial for the synthesis of complex organic molecules.

The physical properties of 1,4-Dimethoxybenzene-d10 include a high boiling point and low volatility compared to its non-deuterated counterpart. These properties are advantageous in analytical techniques such as gas chromatography (GC) and liquid chromatography (LC), where low volatility can reduce sample loss and improve detection limits.

In addition to its applications in analytical chemistry and organic synthesis, 1,4-Dimethoxybenzene-d10 has been explored for its potential in materials science. A recent study published in the Journal of Materials Chemistry demonstrated the use of this compound as a precursor for the synthesis of functionalized polymers with enhanced thermal stability and mechanical strength.

The safety profile of 1,4-Dimethoxybenzene-d10 is generally favorable. However, like any chemical compound, it should be handled with appropriate precautions to ensure safe use. Proper personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn when handling this compound to minimize exposure risks.

In conclusion, 1,4-Dimethoxybenzene-d10 (CAS No. 74079-00-8) is a valuable compound with a wide range of applications in research and industry. Its unique properties make it an essential tool in NMR spectroscopy, organic synthesis, pharmaceutical development, and materials science. Ongoing research continues to uncover new uses for this compound, further solidifying its importance in the scientific community.

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