Cas no 73978-41-3 (2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride)

2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride is a chemically synthesized pteridine derivative with applications in pharmaceutical and biochemical research. Its structure, featuring both amino and hydroxymethyl functional groups, makes it a versatile intermediate for the development of folate analogs and enzyme inhibitors. The hydrochloride salt form enhances solubility and stability, facilitating handling in aqueous solutions. This compound is particularly valuable in studies involving dihydrofolate reductase (DHFR) inhibition and nucleotide biosynthesis pathways. Its high purity and well-defined chemical properties ensure reproducibility in experimental settings, supporting its use in mechanistic and drug discovery research. Proper storage under controlled conditions is recommended to maintain its integrity.
2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride structure
73978-41-3 structure
Product Name:2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride
CAS No:73978-41-3
MF:C7H9ClN6O
MW:228.638958692551
MDL:MFCD00191246
CID:90621
PubChem ID:24878547
Update Time:2025-05-24

2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride Chemical and Physical Properties

Names and Identifiers

    • (2,4-Diaminopteridin-6-yl)methanol hydrochloride
    • (2,4-DIAMINOPTERIDIN-6-YL)METHANOL HYDROCHLORIDE HYDRATE
    • 2,4-DIAMINO-6-(HYDROXYMETHYL)PTERIDINE HYDROCHLORIDE HYDRATE
    • 2,4-Diamino-8-(hydroxymethyl)pteridinehydrochloride
    • 2,4-Diamino-6-(Hydroxymethyl)pteridine HCl
    • 2,4-Diamino-6-(hydroxymethyl)pteridine hydrochloride
    • 2,4-diamino-6-(hydroxymethyl)-pteridine hydrochloride
    • (2,4-DIAMINOPTERIDIN-6-YL)METHANOL HCL
    • 6-Pteridinemethanol, 2,4-diamino-, hydrochloride
    • 2,4-diamino-6-hydroxymethylpteridine hydrochloride
    • 6-Pteridinemethanol, 2,4-diamino-, monohydrochloride
    • (2,4-diaminopteridin-6-yl)methan-1-ol, chloride
    • 2,4-Diamino-6-(hydroxymethyl)pteridinehydrochloride
    • 2,4-diamino-6-(hydroxymethyl)
    • 73978-41-3
    • PS-7744
    • 2,4-Diaminopyrimido[4,5-b]pyrazine-6-methanol monohydrochloride
    • CS-W008143
    • SCHEMBL3101407
    • BCP09302
    • W-200498
    • AKOS005254571
    • FT-0609967
    • (2,4-Diaminopteridin-6-yl)methanol Hydrochloride; Methotrexate Imp. A (EP) as Hydrochloride; Methotrexate Impurity A as Hydrochloride
    • (2,4-diaminopteridin-6-yl)methanol;hydrochloride
    • (2,4-Diamino-6-pteridinyl)methanol hydrochloride
    • (2,4-Diaminopteridin-6-yl)methanolhydrochloridehydrate
    • SY063959
    • (2,4-Diaminopteridin-6-yl)methanolhydrochloride
    • XZHMPUJCSYVIQL-UHFFFAOYSA-N
    • MFCD00191246
    • GEO-00919
    • Methotrexate Imp. as Hydrochloride: (2,4-Diaminopteridin- 6-yl)methanol Hydrochloride
    • (2,4-Diaminopteridin-6-yl)methanol xhydrochloride
    • 2,4-diamino-6-(hydroxymethyl)pteridine hydrocloride
    • 100462-86-0
    • 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride
    • MDL: MFCD00191246
    • Inchi: 1S/C7H8N6O.ClH/c8-5-4-6(13-7(9)12-5)10-1-3(2-14)11-4;/h1,14H,2H2,(H4,8,9,10,12,13);1H
    • InChI Key: XZHMPUJCSYVIQL-UHFFFAOYSA-N
    • SMILES: Cl.OCC1=CN=C2C(C(N)=NC(N)=N2)=N1

Computed Properties

  • Exact Mass: 228.05300
  • Monoisotopic Mass: 228.053
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 4
  • Hydrogen Bond Acceptor Count: 7
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 1
  • Complexity: 203
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 12
  • XLogP3: -1.7
  • Topological Polar Surface Area: 124

Experimental Properties

  • Melting Point: 220?°C (lit.)
  • Boiling Point: 636.5°C at 760 mmHg
  • Flash Point: 338.8°C
  • PSA: 123.83000
  • LogP: 1.04090

2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride Security Information

  • Symbol: GHS07
  • Signal Word:Warning
  • Hazard Statement: H315,H319,H335
  • Warning Statement: P261,P305+P351+P338
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 36/37/38
  • Safety Instruction: S26; S36
  • Hazardous Material Identification: Xi
  • Storage Condition:Keep in dark place,Inert atmosphere,Room temperature
  • Risk Phrases:R36/37/38

2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride Customs Data

  • HS CODE:2933990090
  • Customs Data:

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
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Audited Supplier Audited Supplier
(CAS:73978-41-3)2,4-二氨基-6-羥甲基蝶啶鹽酸鹽
Order Number:LE26800059
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:58
Price ($):discuss personally

2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride Related Literature

Additional information on 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride

Comprehensive Overview of 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride (CAS No. 73978-41-3)

2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride (CAS No. 73978-41-3) is a specialized chemical compound widely recognized for its significance in biochemical research and pharmaceutical applications. This compound, often referred to as a pteridine derivative, has garnered attention due to its unique structural properties and potential utility in various scientific domains. Researchers and industry professionals frequently search for terms like "pteridine derivatives in drug development" or "hydroxymethyl pteridine applications", reflecting the growing interest in its functional versatility.

The molecular structure of 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride features a pteridine core substituted with amino and hydroxymethyl groups, which contribute to its reactivity and solubility. This makes it a valuable intermediate in synthesizing more complex molecules, particularly in the field of medicinal chemistry. Recent studies have explored its role in modulating enzymatic activity, with keywords like "enzyme inhibitors" and "biochemical pathways" trending in academic literature. Its hydrochloride form enhances stability, ensuring consistent performance in experimental settings.

In the context of current research trends, 73978-41-3 has been investigated for its potential in targeted therapy and precision medicine. These areas are highly relevant to modern healthcare, as evidenced by frequent searches for "personalized treatment options" and "small molecule therapeutics". The compound's ability to interact with specific biological targets aligns with the demand for innovative solutions in cancer research and metabolic disorders. Its applications extend to diagnostic reagents, where its fluorescent properties are leveraged for analytical purposes.

From a synthetic perspective, 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride is often utilized as a building block for more complex heterocyclic systems. Chemists frequently inquire about "efficient synthesis routes" or "scalable production methods" for such compounds, highlighting the need for cost-effective and sustainable approaches. The compound's compatibility with green chemistry principles is another area of interest, as industries strive to minimize environmental impact while maintaining high yields.

Quality control and analytical characterization are critical for CAS No. 73978-41-3, with techniques like HPLC, NMR, and mass spectrometry being essential for verification. Researchers often search for "purity standards" and "analytical protocols" to ensure reproducibility in their experiments. The compound's stability under various storage conditions is also a common query, emphasizing the importance of proper handling and documentation in laboratory settings.

In summary, 2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride represents a versatile and scientifically valuable compound with broad applicability. Its relevance to cutting-edge research topics like "drug discovery", "biomarker development", and "therapeutic innovation" ensures its continued prominence in the scientific community. As interest in small molecule therapeutics grows, this compound is poised to play a pivotal role in advancing both academic and industrial research endeavors.

Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:73978-41-3)2,4-二氨基-6-羥甲基蝶啶鹽酸鹽
LE26800059
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
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