Cas no 73821-95-1 ((S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid)
(S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid is a chiral intermediate widely used in organic synthesis and pharmaceutical research. Its key structural features include a Boc-protected amino group and a cyclohexyl ester moiety, making it valuable for peptide coupling and asymmetric synthesis. The tert-butoxycarbonyl (Boc) group enhances stability under basic conditions while allowing selective deprotection under acidic conditions. The cyclohexyl ester provides steric hindrance, influencing reactivity and selectivity in subsequent transformations. This compound is particularly useful in the preparation of modified amino acids and bioactive molecules, offering controlled functionalization and high purity. Its well-defined stereochemistry ensures reproducibility in synthetic applications.
73821-95-1 structure
Product Name:(S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid
CAS No:73821-95-1
MF:C15H25NO6
MW:315.362105131149
MDL:MFCD00061996
CID:59517
PubChem ID:160870992
Update Time:2025-10-16
(S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid Chemical and Physical Properties
Names and Identifiers
-
- boc-L-aspartic acid 4-cyclohexyl ester
- Boc-Asp(OcHex)-OH
- BOC-Asp(OcHx)-OH
- 4-Cyclohexyl N-(tert-Butoxycarbonyl)-L-aspartate
- Boc-L-Asp(OcHex)OH
- Boc-Asp(OcHx)-OH Boc-L-aspartic acid β-cyclohexyl ester
- Boc-L-aspartic acid β-cyclohexyl ester
- N-Alpha-t-Boc-L-aspartic acid beta-cyclohexyl ester
- boc-L-aspartic acid b-cyclohexyl ester
- Boc-L-asparticacid4-cyslohexylester
- N-Boc-L-aspartic Acid 4-Cyclohexyl Ester
- N-(tert-Butoxycarbonyl)-L-aspartic Acid 4-Cyclohexyl Ester
- 4-Cyclohexyl N-Boc-L-aspartate
- (S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid
- (S)-2-(tert-butoxycarbonylamino)-4-(cyclohexyloxy)-4-oxobutanoic acid
- SCHEMBL7109105
- NLPQIWFEEKQBBN-NSHDSACASA-N
- N-alpha-t-Butyloxycarbonyl-L-aspartic acid beta-cyclohexyl ester (Boc-L-Asp(OcHex)-OH)
- PD196813
- HY-W011324
- Boc-Asp(OcHx)-OH, >=98.0% (T)
- Boc-Asp(O-cHex)
- AKOS015922973
- AC-8611
- CS-W012040
- Boc-L-aspartic acid 4-cyslohexyl ester
- 73821-95-1
- DS-13575
- MFCD00061996
- (2S)-4-cyclohexyloxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxobutanoic acid
- C2535
- I10381
- (2S)-2-[(tert-butoxycarbonyl)amino]-4-(cyclohexyloxy)-4-oxobutanoic acid
-
- MDL： MFCD00061996
- Inchi： 1S/C15H25NO6/c1-15(2,3)22-14(20)16-11(13(18)19)9-12(17)21-10-7-5-4-6-8-10/h10-11H,4-9H2,1-3H3,(H,16,20)(H,18,19)/t11-/m0/s1
- InChI Key： NLPQIWFEEKQBBN-NSHDSACASA-N
- SMILES： O(C(C[C@@H](C(=O)O)NC(=O)OC(C)(C)C)=O)C1CCCCC1
Computed Properties
- Exact Mass: 315.16800
- Monoisotopic Mass: 315.16818752g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 7
- Heavy Atom Count: 22
- Rotatable Bond Count: 9
- Complexity: 409
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.2
- Topological Polar Surface Area: 102?2
Experimental Properties
- Color/Form: White powder
- Density: 1.18
- Melting Point: 94.0 to 98.0 deg-C
- Boiling Point: 487.2℃ at 760 mmHg
- Flash Point: 248.4±27.3 °C
- Refractive Index: 1.498
- PSA: 101.93000
- LogP: 2.62120
- Optical Activity: [α]20/D ?21.0±1.5°, c =?2% in DMF
- Solubility: Not determined
(S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
-
Warning Statement：
P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care - Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- Safety Instruction： 24/25
- HazardClass：IRRITANT
- Storage Condition：Storage temperature 2-8 ° C
(S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid Customs Data
- HS CODE：2924299090
- Customs Data：
China Customs Code:
2924299090Overview:
2924299090. Other cyclic amides(Including cyclic carbamates)(Including their derivatives as well as their salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%
Declaration elements:
Product Name, component content, use to, packing
Summary:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
(S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-XM134-25g |
(S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid |
73821-95-1 | 98% | 25g |
340.0CNY | 2021-08-06 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-XM134-5g |
(S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid |
73821-95-1 | 98% | 5g |
122.0CNY | 2021-08-06 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-XM134-1g |
(S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid |
73821-95-1 | 98% | 1g |
50.0CNY | 2021-08-06 | |
| TRC | B391640-250mg |
Boc-L-Asp(OcHx)-OH |
73821-95-1 | 250mg |
$ 64.00 | 2023-04-18 | ||
| TRC | B391640-1g |
Boc-L-Asp(OcHx)-OH |
73821-95-1 | 1g |
$ 60.00 | 2022-06-07 | ||
| TRC | B391640-2.5g |
Boc-L-Asp(OcHx)-OH |
73821-95-1 | 2.5g |
$ 87.00 | 2023-04-18 | ||
| TRC | B391640-5g |
Boc-L-Asp(OcHx)-OH |
73821-95-1 | 5g |
$ 90.00 | 2022-06-07 | ||
| ChemScence | CS-W012040-25g |
(S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid |
73821-95-1 | 25g |
$53.0 | 2022-04-26 | ||
| ChemScence | CS-W012040-100g |
(S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid |
73821-95-1 | 100g |
$102.0 | 2022-04-26 | ||
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | B110961-100g |
(S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid |
73821-95-1 | 99% | 100g |
￥611.90 | 2023-09-04 |
(S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid Related Literature
-
Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
-
Chung-Sung Yang,Mong-Shian Shih,Fang-Yi Chang New J. Chem., 2006,30, 729-735
-
Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
-
Shaun D. Wong,Edward I. Solomon Dalton Trans., 2014,43, 17567-17577
-
Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
73821-95-1 ((S)-2-((tert-Butoxycarbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid) Related Products
- 1164-16-5(Z-Tyr-OH)
- 1234-35-1(Z-L-Arginine)
- 55757-60-3(Boc-L-Lysine Methyl Ester)
- 59768-74-0(Boc-Asp(OMe)-OH)
- 34582-32-6((S)-4-(tert-Butoxy)-3-((tert-butoxycarbonyl)amino)-4-oxobutanoic acid)
- 13726-84-6(Boc-Glu(OtBu)-OH)
- 24277-39-2(Boc-Glu-OtBu)
- 73821-97-3(Boc-L-Glu(OcHx)-OH)
- 1676-90-0(Boc-Asp(OtBu)-OH)
- 1152-61-0(Z-Asp-OH)
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