Cas no 7353-88-0 (3-bromo-2-(chloromethyl)thiophene)
3-Bromo-2-(chloromethyl)thiophene is a versatile heterocyclic compound featuring both bromo and chloromethyl functional groups, making it a valuable intermediate in organic synthesis. The bromine substituent facilitates cross-coupling reactions, such as Suzuki or Stille couplings, while the reactive chloromethyl group allows for further functionalization, including nucleophilic substitutions. This compound is particularly useful in the synthesis of thiophene-based derivatives, which are key scaffolds in pharmaceuticals, agrochemicals, and materials science. Its well-defined reactivity profile and stability under standard conditions ensure consistent performance in multi-step synthetic routes. The product is typically supplied with high purity, ensuring reliable results in research and industrial applications.
7353-88-0 structure
Product Name:3-bromo-2-(chloromethyl)thiophene
CAS No:7353-88-0
MF:C5H4BrClS
MW:211.507258415222
MDL:MFCD13196227
CID:2857390
PubChem ID:12479014
Update Time:2025-05-28
3-bromo-2-(chloromethyl)thiophene Chemical and Physical Properties
Names and Identifiers
-
- 3-bromo-2-(chloromethyl)thiophene
- SCHEMBL6999271
- AT16718
- KYAGPKKOVYJXIY-UHFFFAOYSA-N
- 829-087-0
- 7353-88-0
- A1-06445
- EN300-55413
- AKOS010150040
- 3-bromo-2-(chloromethyl)-thiophene
-
- MDL: MFCD13196227
- Inchi: 1S/C5H4BrClS/c6-4-1-2-8-5(4)3-7/h1-2H,3H2
- InChI Key: KYAGPKKOVYJXIY-UHFFFAOYSA-N
- SMILES: BrC1C=CSC=1CCl
Computed Properties
- Exact Mass: 209.89056Da
- Monoisotopic Mass: 209.89056Da
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 8
- Rotatable Bond Count: 1
- Complexity: 78.8
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.7
- Topological Polar Surface Area: 28.2?2
3-bromo-2-(chloromethyl)thiophene Security Information
- Signal Word:warning
- Hazard Statement: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement: P264+P280+P305+P351+P338+P337+P313
- Safety Instruction: H303+H313+H333
- Storage Condition:storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
3-bromo-2-(chloromethyl)thiophene Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Matrix Scientific | 179781-5g |
3-Bromo-2-(chloromethyl)thiophene, 95% |
7353-88-0 | 95% | 5g |
$1320.00 | 2023-09-05 | |
| TRC | B593740-25mg |
3-bromo-2-(chloromethyl)thiophene |
7353-88-0 | 25mg |
$ 70.00 | 2022-06-07 | ||
| TRC | B593740-50mg |
3-bromo-2-(chloromethyl)thiophene |
7353-88-0 | 50mg |
$ 95.00 | 2022-06-07 | ||
| TRC | B593740-250mg |
3-bromo-2-(chloromethyl)thiophene |
7353-88-0 | 250mg |
$ 340.00 | 2022-06-07 | ||
| Enamine | EN300-55413-0.05g |
3-bromo-2-(chloromethyl)thiophene |
7353-88-0 | 85% | 0.05g |
$91.0 | 2023-02-10 | |
| Enamine | EN300-55413-0.1g |
3-bromo-2-(chloromethyl)thiophene |
7353-88-0 | 85% | 0.1g |
$135.0 | 2023-02-10 | |
| Enamine | EN300-55413-0.25g |
3-bromo-2-(chloromethyl)thiophene |
7353-88-0 | 85% | 0.25g |
$194.0 | 2023-02-10 | |
| Enamine | EN300-55413-0.5g |
3-bromo-2-(chloromethyl)thiophene |
7353-88-0 | 85% | 0.5g |
$306.0 | 2023-02-10 | |
| Enamine | EN300-55413-1.0g |
3-bromo-2-(chloromethyl)thiophene |
7353-88-0 | 85% | 1.0g |
$392.0 | 2023-02-10 | |
| Enamine | EN300-55413-2.5g |
3-bromo-2-(chloromethyl)thiophene |
7353-88-0 | 85% | 2.5g |
$791.0 | 2023-02-10 |
3-bromo-2-(chloromethyl)thiophene Related Literature
-
Jieun Kim,Han-Saem Park,Tae-Hee Kim,Sung Yeol Kim,Hyun-Kon Song Phys. Chem. Chem. Phys., 2014,16, 5295-5300
-
Stephen P. Fletcher,Richard B. C. Jagt,Ben L. Feringa Chem. Commun., 2007, 2578-2580
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Tong Xu,Dongwei Ma,Chengbo Li,Qian Liu,Siyu Lu,Abdullah M. Asiri,Chun Yang,Xuping Sun Chem. Commun., 2020,56, 3673-3676
-
Huiying Xu,Lu Zheng,Yu Zhou,Bang-Ce Ye Analyst, 2021,146, 5542-5549
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5. Agricultural
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