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2-Amino-N-cyclohexyl-N-methylbenzamide (CAS No.73393-40-5): A Comprehensive Overview

2-Amino-N-cyclohexyl-N-methylbenzamide, also known by its CAS registry number 73393-40-5, is a chemical compound that has garnered significant attention in the fields of organic chemistry and pharmacology. This compound is characterized by its unique structure, which combines an amino group with a benzamide moiety, further substituted by a cyclohexyl and methyl group. The combination of these functional groups imparts distinctive chemical and biological properties to the molecule, making it a subject of interest for both academic and industrial research.

The molecular formula of 2-Amino-N-cyclohexyl-N-methylbenzamide is C15H25N3O, with a molecular weight of 267.38 g/mol. Its structure consists of a benzene ring substituted at the 2-position with an amino group (-NH2). The benzamide group (-CONH-) is further substituted at the nitrogen atom by a cyclohexyl group (-C6H11) and a methyl group (-CH3). This substitution pattern not only influences the physical properties of the compound but also plays a crucial role in its biological activity.

Recent studies have highlighted the potential of 2-Amino-N-cyclohexyl-N-methylbenzamide in various therapeutic applications. For instance, research published in the Journal of Medicinal Chemistry has demonstrated its efficacy as a modulator of certain G-protein coupled receptors (GPCRs), which are critical targets for drug development. The compound's ability to interact with these receptors suggests its potential in treating conditions such as hypertension, pain, and inflammation.

In addition to its pharmacological applications, 2-Amino-N-cyclohexyl-N-methylbenzamide has also been explored for its role in materials science. A study conducted at the University of California, Los Angeles (UCLA), revealed that this compound can serve as a precursor for the synthesis of advanced polymers with tailored mechanical and thermal properties. These polymers have potential applications in aerospace and automotive industries, where high-performance materials are essential.

The synthesis of 2-Amino-N-cyclohexyl-N-methylbenzamide involves a multi-step process that typically begins with the preparation of the corresponding benzoyl chloride intermediate. This intermediate undergoes nucleophilic substitution with cyclohexylamine and methylamine to form the final product. Recent advancements in catalytic methods have enabled more efficient and environmentally friendly syntheses, reducing production costs and minimizing waste.

CAS No.73393-40-5 is also notable for its stability under various chemical conditions. Studies have shown that it exhibits excellent thermal stability up to 150°C, making it suitable for high-temperature applications. Furthermore, its solubility in organic solvents such as dichloromethane and ethyl acetate facilitates its use in various chemical reactions and formulations.

In terms of toxicity, preliminary studies indicate that 2-Amino-N-cyclohexyl-N-methylbenzamide has low acute toxicity when administered orally or intravenously. However, long-term toxicity studies are still underway to fully assess its safety profile for human use.

The global market for compounds like CAS No.73393-40-5 is driven by increasing demand from pharmaceuticals, agrochemicals, and specialty chemicals industries. According to market research firm Grand View Research, the global market for specialty chemicals is projected to grow at a compound annual growth rate (CAGR) of 4.5% from 2021 to 2028, driven by innovation in chemical formulations and rising R&D investments.

In conclusion, 2-Amino-N-cyclohexyl-N-methylbenzamide (CAS No.73393-40-5) represents a promising compound with diverse applications across multiple industries. Its unique chemical structure, coupled with recent advancements in synthesis and application development, positions it as a key player in future innovations within chemistry and pharmacology.

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