• 1. An atmosphere and light tuned highly diastereoselective synthesis of cyclobuta/penta[b]indoles from aniline-tethered alkylidenecyclopropanes with alkynes?
  Bo Cao,Yin Wei Chem. Commun., 2018,54, 2870-2873
• 2. An algal process treatment combined with the Fenton reaction for high concentrations of amoxicillin and cefradine
  Haitao Li,Yu Pan,Zhizhi Wang,Shan Chen,Ruixin Guo,Jianqiu Chen RSC Adv., 2015,5, 100775-100782
• 3. Aluminium alkyl and aryloxide complexes of pyrazine and bipyridines: synthesis and structure?
  Doug Ogrin,Laura H. van Poppel,Simon G. Bott,Andrew R. Barron Dalton Trans., 2004, 3689-3694
• 4. An assessment of strategies for the development of solid-state adsorbents for vehicular hydrogen storage
  Mark D. Allendorf,Alauddin Ahmed,Tom Autrey,Jeffrey Camp,Eun Seon Cho,Maciej Haranczyk,Abhi Karkamkar,Di-Jia Liu,Katie R. Meihaus,Iffat H. Nayyar,Roman Nazarov,Donald J. Siegel,Vitalie Stavila,Jeffrey J. Urban,Srimukh Prasad Veccham,Brandon C. Wood Energy Environ. Sci., 2018,11, 2784-2812
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  Eunhak Lim,Jiyoung Heo,Seong Keun Kim Nanoscale, 2019,11, 11369-11378

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Toluenes

Comprehensive Overview of 2-Bromo-3-(3-methylphenyl)-1-propene (CAS No. 731772-18-2): Properties, Applications, and Industry Insights

2-Bromo-3-(3-methylphenyl)-1-propene (CAS No. 731772-18-2) is a specialized organic compound that has garnered significant attention in pharmaceutical and agrochemical research due to its unique structural properties. This brominated aromatic propene derivative serves as a versatile intermediate in synthetic chemistry, particularly in the development of bioactive molecules. Its molecular formula, C₁₀H₁₁Br, and distinct bromo-alkene functionality make it valuable for cross-coupling reactions, a topic frequently searched by chemists exploring palladium-catalyzed transformations.

Recent trends in green chemistry have amplified interest in optimizing the synthesis of compounds like 2-Bromo-3-(3-methylphenyl)-1-propene. Researchers are investigating solvent-free or low-waste methodologies to align with sustainable synthesis principles—a hot topic in 2024. Analytical techniques such as GC-MS and NMR spectroscopy are commonly employed to characterize this compound, addressing frequent queries about halogenated compound analysis.

The compound’s 3-methylphenyl moiety enhances its lipophilicity, making it relevant in drug discovery for modulating pharmacokinetic properties. This aligns with trending searches on fragment-based drug design and small-molecule probes. Notably, its α,β-unsaturated carbonyl analogs (derivable via oxidation) are explored for bioconjugation applications—a rising focus area in proteomics and chemical biology.

Industrial applications of 731772-18-2 include its use in flavor and fragrance intermediates, where its aromatic profile contributes to complex scent formulations. This connects with growing consumer demand for synthetic aroma chemicals in perfumery. Safety data sheets emphasize standard organic lab precautions, avoiding classifications that restrict its research utility.

Emerging discussions in AI-assisted molecular design often reference bromo-alkenes like this compound as building blocks for machine learning-driven synthesis planning. Patent literature reveals its utility in OLED materials, addressing queries about organic electronic compounds. Storage recommendations (2-8°C under inert gas) and compatibility with Grignard reagents are frequently cited in technical forums.

Environmental fate studies of brominated intermediates remain a key search theme, with 731772-18-2 subject to biodegradation assessments under OECD guidelines. Its vinylic bromide reactivity is leveraged in click chemistry modifications—a technique trending in material science circles. Regulatory databases confirm its non-hazardous status for research-scale handling.

In academic settings, this compound features in advanced organic synthesis coursework demonstrating electrophilic addition mechanisms. Suppliers often highlight its ≥95% purity by HPLC, responding to buyer concerns about impurity profiling. Thermal stability data (decomposition >200°C) make it suitable for high-temperature reactions—a niche search keyword among process chemists.

The growing custom synthesis market has increased demand for tailored derivatives of 2-Bromo-3-(3-methylphenyl)-1-propene, particularly for structure-activity relationship studies. Its cLogP value (~3.1) frequently appears in QSAR modeling discussions, bridging computational and experimental chemistry—a crossover topic dominating 2024 conference agendas.

• 62692-40-4(Benzene, (3-bromo-3-butenyl)-)
• 842140-43-6(2-Bromo-3-(4-n-propylphenyl)-1-propene)
• 731772-14-8(2-Bromo-3-(2-methylphenyl)-1-propene)
• 842140-37-8(2-Bromo-3-(3,5-dimethylphenyl)-1-propene)
• 842140-27-6(2-Bromo-3-(4-tert-butylphenyl)-1-propene)
• 116545-04-1(2-Bromo-3-(1-naphthyl)-1-propene)
• 731772-21-7(2-Bromo-3-(4-methylphenyl)-1-propene)
• 842124-28-1(2-Bromo-3-(4-n-butylphenyl)-1-propene)
• 91391-61-6(2-Bromo-3-(4-bromophenyl)-1-propene)
• 485320-31-8(2-Bromo-3-(3-bromophenyl)-1-propene)