Cas no 72741-87-8 (Swainsonine)
Swainsonine is a naturally occurring indolizidine alkaloid with significant biochemical and pharmacological applications. It functions as a potent and selective inhibitor of α-mannosidase and Golgi mannosidase II, disrupting N-linked glycoprotein processing. This mechanism makes it a valuable tool for studying glycoprotein biosynthesis and lysosomal storage disorders. Swainsonine has also demonstrated immunomodulatory and antitumor properties in preclinical research, particularly in altering tumor cell adhesion and metastasis. Its high purity and well-characterized activity ensure reliability for experimental use in glycobiology, oncology, and immunology studies. The compound is typically supplied as a lyophilized powder, ensuring stability and ease of reconstitution for laboratory applications.
Swainsonine structure
Product Name:Swainsonine
CAS No:72741-87-8
MF:C8H15NO3
MW:173.209602594376
MDL:MFCD00017554
CID:568180
PubChem ID:24899779
Update Time:2025-05-28
Swainsonine Chemical and Physical Properties
Names and Identifiers
-
- 1,2,8-Indolizinetriol,octahydro-, (1S,2R,8R,8aR)-
- Swainsonine
- (1S,2R,8R,8aR)-octahydro-1,2,8-indolizinetriol
- (1S,2R,8R,8aR)-octahydroindolizine-1,2,8-triol
- 8A,B-INDOLIZIDINE-1,2A,8B-TRIOL
- D-Swainsonine
- SwainMoia
- swainsonine synthetic
- Tridolgosir
- Tridolgosir Hydrochloride
- (1S,2R,8R,8aR)-1,2,8-Octahydroindolizidinetriol
- (-)-Swainsonine
- RSY4RK37KQ
- 1,2,8-Indolizinetriol, octahydro-, (1S-(1alpha,2alpha,8beta,8abeta))-
- 1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL
- (1S,2R,8R,8aR)-1,2,3,5,6,7,8,8a-octahydroindolizine-1,2,8-triol
- Tridolgosir [INN]
- SWA
- Swainosine
- Locoweed deriv.
- NSC614553
- 1hww
- Octahydro-1,2,8-indolizinetriol
- 1,8-Indolizinetriol, octahydro-, (1S,2R,8R,8aR)-
- CHEBI:9367
- MFCD00017554
- NCGC00163481-04
- HMS1362J09
- BSPBio_001148
- (1S, 2R, 8R, 8AR)-1,2,8-Indolizidinetriol
- HMS3403J09
- Bio1_001183
- NCGC00163481-02
- Bio1_000694
- HMS1792J09
- BDBM50016706
- KBioGR_000488
- AKOS016344385
- 72741-87-8
- Swainsonine (Synthetic)
- DB02034
- DTXCID3026356
- HY-N6722
- NSC-614553
- BB 0261154
- Tox21_112058
- CHEMBL63139
- CHEMBL371197
- KBioSS_000488
- HMS1990J09
- Bio1_000205
- BDBM50168995
- Bio2_000894
- TRIDOLGOSIR [WHO-DD]
- 1,2,8-INDOLIZINETRIOL, OCTAHYDRO-, (1S-(1.ALPHA.,2.ALPHA.,8.BETA.,8A.BETA.))-
- DTXSID5046356
- AC-34386
- 1,8-Indolizinetriol, octahydro-,[1S-(1.alpha.,2.alpha., 8.beta.,8a.beta.)]-
- SR-05000002325
- CCG-208274
- IDI1_002169
- CBiol_001919
- UNII-RSY4RK37KQ
- KBio3_000895
- CS-0015643
- Octahydro-indolizine-1,2,8-triol
- Q415324
- (1S,2R,8aR)-Octahydroindolizinetriol
- SCHEMBL765848
- (1S,2R,8R,8aR)-Octahydro-indolizine-1,2,8-triol
- Octahydro-1,2,8-indolizinetriol hydrochloride
- (-)-(1S,2R,8R,8aR)-1,2,8-Trihydroxyoctahydroindolizine Hydrochloride
- KBio3_000896
- NCGC00163481-03
- CFCE4066-9132-492F-B4E1-B50B974FE148
- Bio2_000414
- KBio2_003056
- SR-05000002325-2
- SMP1_000286
- NS00037401
- KBio2_005624
- 1,2,8-Indolizinetriol, octahydro-, (1S,2R,8R,8aR)-
- CAS-72741-87-8
- KBio2_000488
- SMR002048898
- Swainsonine Hydrochloride
- MLS003389241
- A1IGC
- BRD-K15170068-001-03-2
-
- MDL： MFCD00017554
- Inchi： 1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7-,8-/m1/s1
- InChI Key： FXUAIOOAOAVCGD-WCTZXXKLSA-N
- SMILES： O[C@@H]1[C@@H](CN2CCC[C@H]([C@@H]21)O)O
Computed Properties
- Exact Mass: 173.10500
- Monoisotopic Mass: 173.10519334 g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 12
- Rotatable Bond Count: 0
- Complexity: 176
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Molecular Weight: 173.21
- XLogP3: -1.3
- Topological Polar Surface Area: 63.9
Experimental Properties
- Color/Form: Solids
- Density: 1.38±0.1 g/cm3 (20 oC 760 Torr),
- Melting Point: 144-145 oC
- Boiling Point: 353.3℃/760mmHg
- Flash Point: 209.7±20.7 °C
- Refractive Index: 1.608
- Solubility: Soluble (170 g/l) (25 o C),
- PSA: 63.93000
- LogP: -1.51500
- Solubility: Not determined
- Vapor Pressure: 0.0±1.8 mmHg at 25°C
Swainsonine Security Information
-
Symbol:
- Signal Word：Warning
- Hazard Statement： H302-H312-H332
- Warning Statement： P280
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- Hazard Category Code： 20/21/22
- Safety Instruction： S36
- RTECS：NM2408666
-
Hazardous Material Identification：
- Risk Phrases：R20/21/22
- Storage Condition：2-8°C
Swainsonine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | S8195-1MG |
Swainsonine |
72741-87-8 | 98% | 1mg |
￥4259.48 | 2023-09-16 | |
| TRC | S885000-500μg |
Swainsonine (Synthetic) |
72741-87-8 | 500μg |
45.00 | 2021-07-18 | ||
| TRC | S885000-1mg |
Swainsonine (Synthetic) |
72741-87-8 | 1mg |
$ 114.00 | 2023-09-06 | ||
| TRC | S885000-2mg |
Swainsonine (Synthetic) |
72741-87-8 | 2mg |
$184.00 | 2023-05-17 | ||
| TRC | S885000-5mg |
Swainsonine (Synthetic) |
72741-87-8 | 5mg |
$ 312.00 | 2023-09-06 | ||
| TRC | S885000-10mg |
Swainsonine (Synthetic) |
72741-87-8 | 10mg |
$532.00 | 2023-05-17 | ||
| TRC | S885000-25mg |
Swainsonine (Synthetic) |
72741-87-8 | 25mg |
$ 1000.00 | 2023-09-06 | ||
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajci11994-1mg |
Swainsonine |
72741-87-8 | 98% | 1mg |
￥1328.00 | 2023-09-09 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TN2344-1 mg |
Swainsonine |
72741-87-8 | 1mg |
￥3365.00 | 2022-02-28 | ||
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TN2344-5 mg |
Swainsonine |
72741-87-8 | 5mg |
￥10025.00 | 2022-02-28 |
Swainsonine Suppliers
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:72741-87-8)Swainsonine
Order Number:A962626
Stock Status:in Stock
Quantity:5mg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 16:14
Price ($):692.0
Email:[email protected]
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:72741-87-8)SWAINSONINE
Order Number:1667892
Stock Status:in Stock
Quantity:Company Customization
Purity:98%
Pricing Information Last Updated:Monday, 14 April 2025 21:49
Price ($):discuss personally
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:72741-87-8)八傾吲嗪三醇
Order Number:LE1667892
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:31
Price ($):discuss personally
Email:[email protected]
Swainsonine Related Literature
-
Bin Han,Yasuo Shimizu,Gabriele Seguini,Celia Castro,Gérard Ben Assayag,Koji Inoue,Yasuyoshi Nagai,Sylvie Schamm-Chardon,Michele Perego RSC Adv., 2016,6, 3617-3622
-
Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
-
4. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
-
Dhirendra K. Chaudhary,Pramendra Kumar,Lokendra Kumar RSC Adv., 2016,6, 94731-94738
72741-87-8 (Swainsonine) Related Products
- 214462-68-7((1S,2R,8R,8aR)-1,2,8-Octahydroindolizidinetriol hydrochloride)
- 921199-26-0(3,4-Piperidinediol, 1-dodecyl-2-(hydroxymethyl)-, (2R,3R,4R)-)
- 921199-25-9(3,4-Piperidinediol, 2-(hydroxymethyl)-1-nonyl-, (2R,3R,4R)-)
- 117894-10-7(1,6,7,8-Indolizinetetrol,octahydro-, (1S,6S,7S,8S,8aS)-)
- 117894-11-8(1,6,7,8-Indolizinetetrol,octahydro-, (1R,6S,7S,8S,8aS)-)
- 107244-34-8(6-Epi-castanospermine)
- 79831-76-8(Castanospermine)
- 115649-93-9(6,7,8-Indolizinetriol,octahydro-, (6S,7R,8R,8aR)-)
- 164907-52-2(L-(+)-SWAINSONINE)
- 89955-60-2(1,6,7,8-Indolizinetetrol,octahydro-, (1R,6S,7R,8R,8aR)-)
