Cas no 7252-83-7 (Bromoacetaldehyde dimethyl acetal)

Bromoacetaldehyde dimethyl acetal (CAS 7252-83-7) is a stable, liquid acetal derivative of bromoacetaldehyde, widely used as a versatile intermediate in organic synthesis. Its key advantages include high reactivity as an alkylating agent and compatibility with Grignard and other organometallic reactions. The dimethyl acetal group provides enhanced stability compared to the free aldehyde, reducing polymerization risks while allowing controlled release of bromoacetaldehyde under acidic conditions. This compound is particularly valuable in heterocyclic chemistry, pharmaceutical synthesis, and as a building block for complex molecules. It exhibits good solubility in common organic solvents and is typically handled under inert conditions due to its moisture sensitivity.
Bromoacetaldehyde dimethyl acetal structure
7252-83-7 structure
Product Name:Bromoacetaldehyde dimethyl acetal
CAS No:7252-83-7
MF:C4H9BrO2
MW:169.017060995102
MDL:MFCD00000213
CID:47308
PubChem ID:24854563
Update Time:2026-03-26

Bromoacetaldehyde dimethyl acetal Chemical and Physical Properties

Names and Identifiers

    • 2-Bromo-1,1-dimethoxyethane
    • Bromoacetal dehyde dimethyl acetal
    • Bromoacetaldehyde Dimethyl Acetal (stabilized with K2CO3)
    • 4,5-Dicyano-2-aminoimidazole
    • 2-Bromo-1,1-dimethoxyethane (stabilized with K2CO3)
    • 2,2-Dimethoxyethyl Bromide (stabilized with K2CO3)
    • Bromoacetaldehyde dimethyl acetal
    • Ethane, 2-bromo-1,1-dimethoxy-
    • 2,2-Dimethoxyethyl bromide
    • Dimethylbromoacetal
    • 1-Bromo-2,2-dimethoxyethane
    • 2,2-Dimethoxybromoethane
    • 2-Bromoacetaldehyde dimethyl acetal
    • Bromoacetoaldehyde Dimethyl Acetal
    • Acetaldehyde, bromo-, dimethyl acetal
    • bromoacetaldehyde dimethylacetal
    • 2-bromo-1,1-dimethoxy-ethane
    • FUSFWUFSEJXMRQ-UHFFFAOYSA-N
    • 2-Bromo-1,1-dimethoxyethane, 0.2% potassium carbonate as stabilizer
    • Bromoacetaldehyde
    • bromoacetoaldehyde dimethylacetal
    • CS-W018536
    • 1-bromo-2,2dimethoxyethane
    • P16529
    • FUSFWUFSEJXMRQ-UHFFFAOYSA-
    • 2-Bromo-1,1-dimethoxyethane, 97%
    • 2-bromo-1,1-dimethoxy ethane
    • NSC-73700
    • Q-101943
    • EINECS 230-669-6
    • 7BKM28RJ5D
    • NS00037379
    • bromo-acetaldehyde dimethyl acetal
    • NSC73700
    • 2-bromoethanal dimethyl acetal
    • bromacetaldehyde dimethylacetal
    • 2-bromo-1, 1bis(methyloxy)ethane
    • A837557
    • bromo-acetoaldehyde dimethylacetal
    • AS-13212
    • EN300-68332
    • bromoacetaldehyde dimethyl acetai
    • NSC 73700
    • FT-0625125
    • InChI=1/C4H9BrO2/c1-6-4(3-5)7-2/h4H,3H2,1-2H3
    • F0001-1847
    • B1097
    • 7252-83-7
    • SCHEMBL136821
    • DTXSID2064608
    • 2-bromanyl-1,1-dimethoxy-ethane
    • 1,1-dimethoxy-2-bromoethane
    • 1,1-dimethoxy-2-bromo-ethane
    • bromoacetaldehyde-dimethylacetal
    • AC-2029
    • bromacetaldehyde dimethyl acetal
    • BROMOACETALDEYDE DIMETHYL ACETAL
    • Bromoacetaldehyde diethyl acetal(2-bromide-1,1-diethoxyethane)
    • MFCD00000213
    • ethyl-3-(trimethylsilyl)propynoate
    • AKOS006223686
    • J-802166
    • Bromoacetaldehyde dimethyl acetal 0.2% potassium carbonate as stabilizer
    • 2-bromoacetaldehyde-dimethylacetal
    • PB47370
    • 2-bromoacetaldehyde dimethylacetal
    • 0.2% potassium carbonate as stabilizer, 97%
    • DTXCID1047318
    • DB-027829
    • MDL: MFCD00000213
    • Inchi: 1S/C4H9BrO2/c1-6-4(3-5)7-2/h4H,3H2,1-2H3
    • InChI Key: FUSFWUFSEJXMRQ-UHFFFAOYSA-N
    • SMILES: BrCC(OC)OC
    • BRN: 1280132

Computed Properties

  • Exact Mass: 167.97900
  • Monoisotopic Mass: 167.979
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 7
  • Rotatable Bond Count: 3
  • Complexity: 36.7
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 0.9
  • Topological Polar Surface Area: 18.5

Experimental Properties

  • Color/Form: Colorless liquid
  • Density: 1.43?g/mL?at 25?°C(lit.)
  • Boiling Point: 150°C(lit.)
  • Flash Point: Degrees Fahrenheit:123.8°F
    Degrees Celsius:51°C
  • Refractive Index: n20/D 1.445(lit.)
  • Water Partition Coefficient: Insoluble
  • PSA: 18.46000
  • LogP: 1.00020
  • Sensitiveness: Moisture Sensitive
  • Solubility: Soluble in water

Bromoacetaldehyde dimethyl acetal Security Information

  • Symbol: GHS02 GHS07
  • Prompt:warning
  • Signal Word:Warning
  • Hazard Statement: H226,H319
  • Warning Statement: P305+P351+P338
  • Hazardous Material transportation number:UN 1989 3/PG 3
  • WGK Germany:3
  • Hazard Category Code: 10-36
  • Safety Instruction: S26-S36/39-S28A-S16
  • FLUKA BRAND F CODES:8-9-21
  • Hazardous Material Identification: Xi
  • HazardClass:3
  • PackingGroup:III
  • TSCA:Yes
  • Storage Condition:2-8°C
  • Risk Phrases:R10; R36/37/38
  • Packing Group:III
  • Safety Term:3
  • Packing Group:III
  • Hazard Level:3

Bromoacetaldehyde dimethyl acetal Customs Data

  • HS CODE:29110000
  • Customs Data:

    China Customs Code:

    2911000000

    Overview:

    2911000000 Acetals and hemiacetals,Whether or not containing other oxygen-containing groups,And its halogenation,sulfonation,Nitration and nitrosation derivatives.Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:5.5%.general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2911000000 acetals and hemiacetals, whether or not with other oxygen function, and their halogenated, sulphonated, nitrated or nitrosated derivatives.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:5.5%.General tariff:30.0%

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Bromoacetaldehyde dimethyl acetal Suppliers

Amadis Chemical Company Limited
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(CAS:7252-83-7)Bromoacetaldehyde dimethyl acetal
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(CAS:7252-83-7)Bromoacetaldehyde dimethyl acetal
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(CAS:7252-83-7)2-溴-1,1-二甲氧基乙烷
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Bromoacetaldehyde dimethyl acetal Spectrogram

1H NMR 300 MHz DMSO
1H NMR
13C NMR
13C NMR
GC-MS
GC-MS

Additional information on Bromoacetaldehyde dimethyl acetal

Introduction to Bromoacetaldehyde dimethyl acetal (CAS No. 7252-83-7)

Bromoacetaldehyde dimethyl acetal, with the chemical formula CAS No. 7252-83-7, is a significant compound in the field of organic synthesis and pharmaceutical research. This organobromine compound, characterized by its reactive aldehyde and bromo substituents, has garnered considerable attention due to its versatile applications in the synthesis of fine chemicals and biologically active molecules. The unique structural features of Bromoacetaldehyde dimethyl acetal make it a valuable intermediate in the development of novel therapeutic agents, particularly in the realm of medicinal chemistry.

The reactivity of Bromoacetaldehyde dimethyl acetal stems from its dual functional groups: the aldehyde moiety and the bromine atom. The aldehyde group serves as a nucleophilic acceptor, enabling condensation reactions with amines and other nucleophiles to form imines or Schiff bases. Meanwhile, the bromine atom introduces electrophilic characteristics, facilitating substitution reactions such as Suzuki-Miyaura cross-coupling, which is pivotal in constructing complex molecular architectures. These properties have positioned Bromoacetaldehyde dimethyl acetal as a cornerstone in synthetic methodologies across multiple disciplines.

In recent years, advancements in synthetic chemistry have highlighted the utility of Bromoacetaldehyde dimethyl acetal in drug discovery initiatives. Its role as a precursor in the synthesis of heterocyclic compounds has been particularly noteworthy. For instance, researchers have leveraged its reactivity to develop novel scaffolds for antimicrobial and anti-inflammatory agents. The ability to introduce diverse functional groups through subsequent transformations makes Bromoacetaldehyde dimethyl acetal an indispensable tool for medicinal chemists seeking to optimize bioactivity and pharmacokinetic profiles.

Moreover, the application of Bromoacetaldehyde dimethyl acetal extends beyond pharmaceuticals into agrochemicals and materials science. In agrochemical research, its derivatives have been explored for their potential as intermediates in the synthesis of pesticides and herbicides. The structural adaptability of this compound allows chemists to tailor molecular properties for specific biological targets, enhancing efficacy while minimizing environmental impact.

Recent studies have also demonstrated the significance of Bromoacetaldehyde dimethyl acetal in catalytic processes. The compound has been employed as a ligand or co-catalyst in various organic transformations, improving reaction yields and selectivity. This underscores its importance not only as a building block but also as a facilitator of efficient synthetic routes. The integration of Bromoacetaldehyde dimethyl acetal into continuous flow chemistry systems has further expanded its utility, enabling scalable and sustainable production methods.

The industrial production of Bromoacetaldehyde dimethyl acetal (CAS No. 7252-83-7) adheres to stringent quality control measures to ensure consistency and purity. Manufacturers employ advanced purification techniques such as distillation or crystallization to isolate the compound from impurities, guaranteeing its suitability for high-value applications. As demand grows for specialized intermediates like Bromoacetaldehyde dimethyl acetal, innovations in synthetic processes continue to emerge, driven by the need for more efficient and environmentally friendly methodologies.

The future prospects of Bromoacetaldehyde dimethyl acetal are promising, with ongoing research exploring new derivatives and applications. Collaborative efforts between academia and industry are fostering innovative approaches to harness its potential fully. As synthetic methodologies evolve, so too will the role of this versatile compound in shaping advancements across multiple scientific domains.

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Amadis Chemical Company Limited
(CAS:7252-83-7)Bromoacetaldehyde dimethyl acetal
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Suzhou Senfeida Chemical Co., Ltd
(CAS:7252-83-7)Bromoacetaldehyde dimethyl acetal
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