Cas no 72519-12-1 (1H-Pyrrole-3-carboxylicacid, 2,5-dihydro-)
1H-Pyrrole-3-carboxylicacid, 2,5-dihydro- Chemical and Physical Properties
Names and Identifiers
-
- 1H-Pyrrole-3-carboxylicacid, 2,5-dihydro-
- 3-Pyrroline-3-carboxylicacid
- 1H-Pyrrole-3-carboxylicacid,2,5-dihydro-(9CI)
- 72519-12-1
- 3-Pyrroline-3-carboxylic acid
- AKOS006373460
- AMY32011
- BDBM50000101
- 2,5-Dihydro-1H-pyrrole-3-carboxylicacid
- EN300-6445913
- SCHEMBL17897341
- 2,5-dihydro-1h-pyrrol-3-carboxylic acid
- CHEMBL311110
- 2,5-Dihydro-1H-pyrrole-3-carboxylic acid
-
- Inchi: 1S/C5H7NO2/c7-5(8)4-1-2-6-3-4/h1,6H,2-3H2,(H,7,8)
- InChI Key: OFXLSRPKPVZWLT-UHFFFAOYSA-N
- SMILES: OC(C1=CCNC1)=O
Computed Properties
- Exact Mass: 113.04771
- Monoisotopic Mass: 113.048
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 8
- Rotatable Bond Count: 1
- Complexity: 139
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 49.3A^2
- XLogP3: -3
Experimental Properties
- PSA: 49.33
1H-Pyrrole-3-carboxylicacid, 2,5-dihydro- Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM524544-1g |
2,5-Dihydro-1H-pyrrole-3-carboxylic acid |
72519-12-1 | 96% | 1g |
$1267 | 2024-07-24 | |
| Chemenu | CM524544-5g |
2,5-Dihydro-1H-pyrrole-3-carboxylic acid |
72519-12-1 | 96% | 5g |
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| Enamine | EN300-6445913-0.05g |
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72519-12-1 | 0.05g |
$491.0 | 2023-05-25 | ||
| Enamine | EN300-6445913-0.1g |
2,5-dihydro-1H-pyrrole-3-carboxylic acid |
72519-12-1 | 0.1g |
$515.0 | 2023-05-25 | ||
| Enamine | EN300-6445913-0.25g |
2,5-dihydro-1H-pyrrole-3-carboxylic acid |
72519-12-1 | 0.25g |
$538.0 | 2023-05-25 | ||
| Enamine | EN300-6445913-0.5g |
2,5-dihydro-1H-pyrrole-3-carboxylic acid |
72519-12-1 | 0.5g |
$561.0 | 2023-05-25 | ||
| Enamine | EN300-6445913-1.0g |
2,5-dihydro-1H-pyrrole-3-carboxylic acid |
72519-12-1 | 1g |
$584.0 | 2023-05-25 | ||
| Enamine | EN300-6445913-2.5g |
2,5-dihydro-1H-pyrrole-3-carboxylic acid |
72519-12-1 | 2.5g |
$1147.0 | 2023-05-25 | ||
| Enamine | EN300-6445913-5.0g |
2,5-dihydro-1H-pyrrole-3-carboxylic acid |
72519-12-1 | 5g |
$1695.0 | 2023-05-25 | ||
| Enamine | EN300-6445913-10.0g |
2,5-dihydro-1H-pyrrole-3-carboxylic acid |
72519-12-1 | 10g |
$2516.0 | 2023-05-25 |
1H-Pyrrole-3-carboxylicacid, 2,5-dihydro- Related Literature
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Huabin Zhang,Shaowu Du CrystEngComm, 2014,16, 4059-4068
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Li-Hua Gan,Rui Wu,Jian-Lei Tian,Patrick W. Fowler Phys. Chem. Chem. Phys., 2017,19, 419-425
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Jialiang Yuan,Ran Dong,Yuan Li,Yang Liu,Zhuo Zheng,Yuxia Liu,Yan Sun,Benhe Zhong,Zhenguo Wu,Xiaodong Guo Chem. Commun., 2021,57, 13004-13007
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Supaporn Sawadjoon,Joseph S. M. Samec Org. Biomol. Chem., 2011,9, 2548-2554
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5. An autonomous self-optimizing flow machine for the synthesis of pyridine–oxazoline (PyOX) ligands?Eric Wimmer,Daniel Cortés-Borda,Solène Brochard,Elvina Barré,Charlotte Truchet,Fran?ois-Xavier Felpin React. Chem. Eng., 2019,4, 1608-1615
Additional information on 1H-Pyrrole-3-carboxylicacid, 2,5-dihydro-
Exploring the Versatile Applications of 1H-Pyrrole-3-carboxylicacid, 2,5-dihydro- (CAS No. 72519-12-1)
In the ever-evolving landscape of organic chemistry, 1H-Pyrrole-3-carboxylicacid, 2,5-dihydro- (CAS No. 72519-12-1) has emerged as a compound of significant interest to researchers and industry professionals alike. This heterocyclic compound, characterized by its unique pyrrole ring structure and carboxylic acid functionality, serves as a crucial building block in pharmaceutical synthesis and material science applications.
The molecular structure of 2,5-dihydro-1H-pyrrole-3-carboxylic acid features a partially saturated pyrrole core, which contributes to its enhanced stability compared to fully aromatic pyrrole derivatives. This structural characteristic makes it particularly valuable in medicinal chemistry, where researchers are actively exploring its potential as a precursor for novel drug candidates. Recent studies have highlighted its role in developing treatments for neurological disorders, a topic that has gained substantial attention in scientific communities and healthcare discussions.
From a synthetic chemistry perspective, the carboxylic acid group in 1H-Pyrrole-3-carboxylicacid, 2,5-dihydro- offers multiple sites for chemical modification, enabling the creation of diverse derivatives. This versatility aligns perfectly with current trends in green chemistry and sustainable synthesis, as researchers seek more efficient methods to functionalize such heterocyclic compounds with minimal environmental impact. The compound's compatibility with various coupling reactions makes it particularly valuable in peptide mimetics development, addressing the growing demand for innovative therapeutic approaches.
The pharmaceutical industry has shown increasing interest in dihydro-pyrrole carboxylic acid derivatives due to their potential biological activities. Computational chemistry studies suggest that these structures may interact favorably with various enzyme targets, sparking investigations into their use for anti-inflammatory and neuroprotective applications. These research directions correspond with trending searches in scientific databases regarding novel approaches to managing chronic inflammation and neurodegenerative conditions.
In material science, the 2,5-dihydro-1H-pyrrole-3-carboxylic acid scaffold has demonstrated promise in the development of organic electronic materials. Its ability to participate in conjugation systems while maintaining processability makes it attractive for organic semiconductor applications. This aligns with current industry focus on flexible electronics and biodegradable materials, topics that frequently appear in technology and sustainability discussions.
The synthesis and characterization of 1H-Pyrrole-3-carboxylicacid, 2,5-dihydro- continue to be active areas of research, with recent publications highlighting improved synthetic routes that enhance yield and purity. Analytical techniques such as HPLC and NMR spectroscopy play crucial roles in quality control, ensuring the compound meets the stringent requirements of pharmaceutical applications. These analytical aspects respond to common queries from quality control professionals and researchers working with heterocyclic compounds.
As the scientific community places greater emphasis on structure-activity relationships, the dihydro-pyrrole carboxylic acid framework offers valuable insights into molecular design principles. Its study contributes to our understanding of how partial saturation in heterocyclic systems affects biological activity and physical properties—a subject of numerous recent review articles and conference presentations.
The commercial availability of 1H-Pyrrole-3-carboxylicacid, 2,5-dihydro- (CAS 72519-12-1) from specialized chemical suppliers has facilitated its adoption in various research programs. Current market analysis indicates growing demand for such fine chemicals, particularly in regions with strong pharmaceutical and biotechnology sectors. This trend mirrors broader industry movements toward specialized intermediates for drug discovery.
Looking forward, the applications of 2,5-dihydro-1H-pyrrole-3-carboxylic acid are expected to expand into emerging fields such as bioconjugation chemistry and targeted drug delivery systems. These applications capitalize on the compound's dual functionality and compatibility with biological systems, addressing current challenges in precision medicine—a frequently searched topic in both academic and medical circles.
For researchers considering working with 1H-Pyrrole-3-carboxylicacid, 2,5-dihydro-, proper handling and storage recommendations include protection from moisture and oxidation. While not classified as hazardous, standard laboratory precautions for organic acids should be observed. These practical considerations respond to common queries from first-time users of such specialized chemical intermediates.
The ongoing exploration of dihydro-pyrrole derivatives in scientific literature demonstrates the enduring relevance of this chemical class. With each new study, our understanding of 1H-Pyrrole-3-carboxylicacid, 2,5-dihydro- deepens, revealing additional potential applications and synthetic possibilities that keep this compound at the forefront of heterocyclic chemistry research.
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