Cas no 72218-68-9 (2'-Bromo-2'-deoxyuridine)

2'-Bromo-2'-deoxyuridine (BrdU) is a thymidine analog widely used in biochemical and cellular research. Its primary advantage lies in its ability to incorporate into newly synthesized DNA, serving as a marker for cell proliferation studies. The bromine substitution at the 2' position enhances its detection sensitivity via immunostaining or fluorescence microscopy when paired with anti-BrdU antibodies. This compound is particularly valuable in tracking DNA replication dynamics, assessing cell cycle progression, and investigating neural or cancer cell proliferation. Its stability and compatibility with standard laboratory techniques make it a reliable tool for in vitro and in vivo applications. BrdU is also utilized in studies involving DNA repair mechanisms and stem cell research.
2'-Bromo-2'-deoxyuridine structure
2'-Bromo-2'-deoxyuridine structure
Product Name:2'-Bromo-2'-deoxyuridine
CAS No:72218-68-9
MF:C9H11BrN2O5
MW:307.098041772842
MDL:MFCD06658226
CID:59327
PubChem ID:188257
Update Time:2025-11-06

2'-Bromo-2'-deoxyuridine Chemical and Physical Properties

Names and Identifiers

    • 2'-Bromo-2'-deoxyuridine
    • 1-[(2R,3R,4R,5R)-3-Bromo-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
    • AKOS015919385
    • 1-(2-Bromo-2-deoxy-beta-D-xylofuranosyl)uracil
    • 1-((2R,3R,4R,5R)-3-bromo-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
    • 72218-68-9
    • HG1157
    • FEUDNSHXOOLCEY-XVFCMESISA-N
    • A917530
    • 2'-bromodesoxyuridine
    • SCHEMBL2056539
    • 4753-02-0
    • J-700030
    • 1-(2-Bromo-2-deoxypentofuranosyl)-4-hydroxypyrimidin-2(1H)-one
    • DTXSID60992952
    • 2-bromo-2-deoxyuridine
    • 2'-Bromo-2'-deoxy-D-uridine
    • XCA21868
    • AKOS015834000
    • 1-[(2R,3R,4R,5R)-3-bromo-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
    • DB-313607
    • 2'-Bromo-2'-deoxyuridin
    • MDL: MFCD06658226
    • Inchi: 1S/C9H11BrN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6-,7-,8-/m1/s1
    • InChI Key: FEUDNSHXOOLCEY-XVFCMESISA-N
    • SMILES: Br[C@H]1[C@H](N2C=CC(NC2=O)=O)O[C@H](CO)[C@H]1O

Computed Properties

  • Exact Mass: 305.98500
  • Monoisotopic Mass: 305.985
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 2
  • Complexity: 374
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 4
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: _0.5
  • Topological Polar Surface Area: 99.1A^2

Experimental Properties

  • Color/Form: No data available
  • Density: 1.882 g/cm3
  • Melting Point: No data available
  • Boiling Point: No data available
  • Flash Point: No data available
  • Refractive Index: 1.641
  • Water Partition Coefficient: Soluble in water.
  • PSA: 104.55000
  • LogP: -1.44930

2'-Bromo-2'-deoxyuridine Customs Data

  • HS CODE:2934999090
  • Customs Data:

    China Customs Code:

    2934999090

    Overview:

    2934999090. Other heterocyclic compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2'-Bromo-2'-deoxyuridine Pricemore >>

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2'-Bromo-2'-deoxyuridine Suppliers

NewCan Biotech Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:72218-68-9)2'-Bromo-2'-deoxyuridine
Order Number:NC13704
Stock Status:
Quantity:10g
Purity:97%
Pricing Information Last Updated:Friday, 18 July 2025 16:03
Price ($):Price inquiry

Additional information on 2'-Bromo-2'-deoxyuridine

Market Research and Analysis of 2'-Bromo-2'-deoxyuridine (72218-68-9) in Chemical-Biomedical Fields

2'-Bromo-2'-deoxyuridine, identified by the CAS number 72218-68-9, is a critical compound in the fields of chemistry, biology, and medicine. This nucleoside analog has garnered significant attention due to its unique properties and applications in research and therapeutic development.

The compound is widely utilized in molecular biology as a marker for DNA synthesis. Its bromine substitution at the 5-position of the uracil ring makes it an ideal substrate for DNA polymerases, enabling its incorporation into DNA strands during replication. This feature has made it invaluable in studies related to DNA replication, repair, and antiviral research.

Market demand for 2'-Bromo-2'-deoxyuridine is driven by its role in antiviral drug development. The compound serves as a precursor for the synthesis of nucleoside analogs that inhibit viral replication, particularly in the case of herpes simplex virus (HSV) and other DNA viruses. Its potential as an antiviral agent has led to increased interest from pharmaceutical companies and research institutions.

Global suppliers of 72218-68-9 cater to both academic and industrial needs. The product is available in various purities and forms, depending on the specific application requirements. Key suppliers are focused on maintaining high-quality standards to meet the stringent demands of the chemical and biomedical industries.

Purchasing trends indicate a steady increase in demand, particularly from regions with advanced pharmaceutical research capabilities. The compound's versatility across multiple research applications ensures its continued relevance in both basic science and applied medicine.

Recommended suppliers
NewCan Biotech Limited
(CAS:72218-68-9)2'-Bromo-2'-deoxyuridine
NC13704
Purity:97%
Quantity:10g
Price ($):Inquiry
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