Cas no 71989-43-0 (H-Thr(tBu)-OMe.HCl)
H-Thr(tBu)-OMe·HCl is a protected derivative of threonine, where the hydroxyl group is tert-butylated (tBu) and the carboxyl group is methyl-esterified (OMe). This compound is commonly used in peptide synthesis to prevent unwanted side reactions during coupling steps. The tert-butyl protection enhances stability under acidic conditions, while the methyl ester facilitates solubility in organic solvents. The hydrochloride (HCl) salt form improves handling and storage. This reagent is particularly valuable in solid-phase peptide synthesis (SPPS) and solution-phase methods, offering controlled deprotection kinetics and compatibility with standard Fmoc/tBu strategies. Its high purity and consistent performance make it a reliable choice for complex peptide assembly.
H-Thr(tBu)-OMe.HCl structure
Product Name:H-Thr(tBu)-OMe.HCl
CAS No:71989-43-0
MF:C9H20ClNO3
MW:225.713002204895
MDL:MFCD00077111
CID:95359
PubChem ID:16218568
Update Time:2025-10-17
H-Thr(tBu)-OMe.HCl Chemical and Physical Properties
Names and Identifiers
-
- O-tert-Butyl-L-threonine methyl ester hydrochloride
- H-Thr(tBu)-OMe.HCl
- (2S,3R)-Methyl 2-amino-3-(tert-butoxy)butanoate hydrochloride
- H-L-Thr(tBu)-OMe*HCl
- H-Thr(But)-OmeHCl
- H-THR(TBU)-OME HCL
- H-Thr(tBu)-OMe·HCl
- H-Thr(tBu)-OMe?HCl
- H-Thr(tBu)-OMe?HCl
- O-T-Butyl-L-Threonine Methyl Ester Hydrochlorid
- (O-t-Bu)-L-Thr-OMe
- 81655_ALDRICH
- 81655_FLUKA
- A7397
- AG-B-40419
- CTK3J1720
- H-Thr(But)-OMe*HCl
- KSC491O2B
- methyl O-(1,1-dimethylethyl)-L-threoninate hydrochloride
- O-t-butylthreonine methyl ester hydrochloride
- O-tert-butylthreonine methyl ester hydrochloride
- O-T-Butyl-L-Threonine Methyl Ester Hydrochloride
- L-Threonine, O-(1,1-dimethylethyl)-, methyl ester, hydrochloride
- H-Thr(tBU)-OMe hydrochloride
- H-Thr(t-Bu)-OMe*HCl;
- SDHKEUUZUMQSAD-HHQFNNIRSA-N
- 1173
-
- MDL： MFCD00077111
- Inchi： 1S/C9H19NO3.ClH/c1-6(13-9(2,3)4)7(10)8(11)12-5;/h6-7H,10H2,1-5H3;1H/t6-,7+;/m1./s1
- InChI Key： SDHKEUUZUMQSAD-HHQFNNIRSA-N
- SMILES： Cl.O([C@H](C)[C@@H](C(=O)OC)N)C(C)(C)C
Computed Properties
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 14
- Rotatable Bond Count: 5
- Complexity: 174
- Topological Polar Surface Area: 61.6
Experimental Properties
- Boiling Point: 289.8℃ at 760 mmHg
H-Thr(tBu)-OMe.HCl Security Information
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- Storage Condition：2-8°C
H-Thr(tBu)-OMe.HCl Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM119467-25g |
O-tert-Butyl-L-threonine Methyl Ester Hydrochloride |
71989-43-0 | 95% | 25g |
$102 | 2021-06-09 | |
| Chemenu | CM119467-100g |
O-tert-Butyl-L-threonine Methyl Ester Hydrochloride |
71989-43-0 | 95% | 100g |
$243 | 2021-06-09 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-SI787-100g |
H-Thr(tBu)-OMe.HCl |
71989-43-0 | 97% | 100g |
1652.0CNY | 2021-07-12 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-SI787-20g |
H-Thr(tBu)-OMe.HCl |
71989-43-0 | 97% | 20g |
371.0CNY | 2021-07-12 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-SI787-25g |
H-Thr(tBu)-OMe.HCl |
71989-43-0 | 97% | 25g |
735CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-SI787-5g |
H-Thr(tBu)-OMe.HCl |
71989-43-0 | 97% | 5g |
139.0CNY | 2021-07-12 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-SI787-1g |
H-Thr(tBu)-OMe.HCl |
71989-43-0 | 97% | 1g |
64CNY | 2021-05-08 | |
| abcr | AB165156-1 g |
O-t-Butyl-L-threonine methyl ester hydrochloride; . |
71989-43-0 | 1g |
€68.80 | 2022-06-11 | ||
| abcr | AB165156-5 g |
O-t-Butyl-L-threonine methyl ester hydrochloride; . |
71989-43-0 | 5g |
€74.10 | 2022-06-11 | ||
| AAPPTec | AHT126-5g |
H-Thr(tBu)-OMe HCl |
71989-43-0 | 5g |
$55.00 | 2024-07-19 |
H-Thr(tBu)-OMe.HCl Related Literature
-
Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu Ma RSC Adv., 2021,11, 37631-37642
-
Li-Hua Gan,Rui Wu,Jian-Lei Tian,Patrick W. Fowler Phys. Chem. Chem. Phys., 2017,19, 419-425
-
Ni-Na Sun,Fengli Qu,Xiaobing Zhang,Shufang Zhang,Jinmao You Analyst, 2015,140, 1827-1831
-
Yang Chen,Di Zhou,Zheyi Meng,Jin Zhai Chem. Commun., 2016,52, 10020-10023
-
5. An all-solid-state imprinted polymer-based potentiometric sensor for determination of bisphenol S?Rongning Liang,Tanji Yin,Ruiqing Yao,Wei Qin RSC Adv., 2016,6, 73308-73312
71989-43-0 (H-Thr(tBu)-OMe.HCl) Related Products
- 5854-77-3((2S,3R)-tert-Butyl 2-amino-3-(tert-butoxy)butanoate Acetate)
- 61215-09-6(Threonine, O-(1,1-dimethylethyl)-, methyl ester)
- 69320-90-7(L-Threonine tert-Butyl Ester Hydrochloride)
- 78061-03-7(H-THR-OTBU ACOH)
- 5854-78-4(O-tert-Butylthreoninetert-butyl ester)
- 66748-90-1(tert-butyl (2S,3R)-2-amino-3-hydroxybutanoate)
- 519156-32-2(H-Thr(Ac)-OH Hydrochloride)
- 24205-25-2(methyl (2S,3R)-2-amino-3-(tert-butoxy)butanoate)
- 38024-14-5(DL-Threonine, O-(1,1-dimethylethyl)-, 1,1-dimethylethyl ester, acetate)
- 115141-43-0(O-tert-Butyl-D-threonine methyl ester hydrochloride)
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