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  J. Xu,T. J. Carrocci,A. A. Hoskins Chem. Commun., 2016,52, 549-552
• 2. Enabling high-throughput single-animal gene-expression studies with molecular and micro-scale technologies
  Jason Wan Lab Chip, 2020,20, 4528-4538
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• Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides

Comprehensive Overview of 5-Chloro-4-methyl-2-nitroaniline (CAS No. 7149-80-6): Properties, Applications, and Industry Insights

5-Chloro-4-methyl-2-nitroaniline (CAS No. 7149-80-6) is a specialized organic compound widely recognized in the chemical and pharmaceutical industries. This nitroaniline derivative features a unique molecular structure, combining a chloro group, a methyl group, and a nitro group on an aniline backbone. Its distinct properties make it valuable for synthesizing dyes, agrochemicals, and pharmaceutical intermediates. Researchers and manufacturers frequently search for terms like "5-Chloro-4-methyl-2-nitroaniline synthesis," "CAS 7149-80-6 suppliers," and "nitroaniline applications," reflecting its commercial and scientific relevance.

The compound's molecular formula (C7H7ClN2O2) and molecular weight (186.6 g/mol) are critical for stoichiometric calculations in synthetic processes. Its yellow crystalline appearance and moderate solubility in organic solvents like ethanol and acetone make it suitable for controlled reactions. Recent trends highlight growing interest in "sustainable synthesis of nitroaromatics" and "green chemistry alternatives," prompting innovations in catalytic methods to produce 5-Chloro-4-methyl-2-nitroaniline with reduced environmental impact.

In the dye industry, 5-Chloro-4-methyl-2-nitroaniline serves as a precursor for azo dyes, which are pivotal in textile and pigment manufacturing. Searches for "azo dye intermediates" and "eco-friendly dye synthesis" correlate with its usage. Additionally, its role in agrochemicals—such as herbicides and fungicides—aligns with the rising demand for "crop protection chemicals" and "high-efficiency pesticides." Regulatory compliance, especially concerning "REACH certification" and "OECD guidelines," further underscores its safe handling protocols.

From a pharmacological perspective, this compound is explored for designing bioactive molecules, particularly in antimicrobial and anti-inflammatory research. Queries like "nitroaniline medicinal chemistry" and "drug discovery intermediates" reflect its potential. Analytical techniques such as HPLC, GC-MS, and NMR spectroscopy are essential for purity verification, addressing quality concerns like "CAS 7149-80-6 purity standards."

Storage and handling of 5-Chloro-4-methyl-2-nitroaniline require attention to stability under ambient conditions, with recommendations to avoid prolonged light exposure. Industry discussions often focus on "chemical storage best practices" and "handling hazardous intermediates," though this compound is classified as non-explosive. Its melting point (128–132°C) and thermal decomposition data are vital for process safety evaluations.

Market analyses reveal increasing procurement of CAS 7149-80-6 from Asia-Pacific regions, driven by expansions in specialty chemicals. Keywords like "global chemical distributors" and "bulk nitroaniline suppliers" highlight supply chain dynamics. Future applications may include advanced materials, such as organic semiconductors, aligning with trends in "electronic materials research."

In summary, 5-Chloro-4-methyl-2-nitroaniline (CAS No. 7149-80-6) bridges multiple industries through its versatile reactivity. Its optimization via catalytic hydrogenation or microwave-assisted synthesis responds to demands for "energy-efficient chemical processes." As research evolves, this compound will remain integral to innovations in functional materials and life sciences.

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