Cas no 71461-30-8 (1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)-)

The compound (2S)-1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester is a chiral pyrrolidine derivative with significant utility in organic synthesis and pharmaceutical applications. Its key structural features include a formyl group at the 2-position and a benzyl ester moiety, enhancing its reactivity as an intermediate in asymmetric synthesis. The (S)-configuration ensures stereoselectivity in reactions, making it valuable for constructing enantiomerically pure compounds. Its stability under standard conditions and compatibility with various coupling reagents further underscore its versatility. This compound is particularly useful in peptide modifications and the preparation of bioactive molecules, offering precise control over molecular architecture in medicinal chemistry and catalysis.
1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)- structure
71461-30-8 structure
Product Name:1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)-
CAS No:71461-30-8
MF:C13H15NO3
MW:233.263103723526
MDL:MFCD17214732
CID:545502
PubChem ID:11746545
Update Time:2025-11-02

1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)- Chemical and Physical Properties

Names and Identifiers

    • 1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)-
    • (S)-2-FORMYL-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER
    • N-Cbz-L-prolinal
    • (2S)-(-)-phenylmethyl 2-formylpyrrolidine-1-carboxylate
    • (2S)-N-Cbz-pyrrolidine-2-carboxaldehyde
    • (S)-N-carbobenzyloxyprolinal
    • (S)-N-Cbz-prolinal
    • 1-Pyrrolidinecarboxylic acid,2-formyl-,phenylmethyl ester,(2S)
    • Cbz-(S)-prolinal
    • N-benzyloxycarbonyl prolinal
    • Z-L-prolinal
    • (S)-Benzyl 2-formylpyrrolidine-1-carboxylate
    • Benzyl (2S)-2-formylpyrrolidine-1-carboxylate
    • Carbobenzyloxy-L-prolinal
    • N-(Benzyloxycarbonyl)-L-prolinal
    • N-(Carbobenzyloxy)-L-prolinal
    • AM101184
    • Benzyl (S)-2-formylpyrrolidine-1-carboxylate
    • MFCD17214732
    • SCHEMBL2198909
    • DTXSID90471765
    • CBZ-L-prolinal
    • ASNHSGGMNWXBEI-LBPRGKRZSA-N
    • AKOS017344706
    • 71461-30-8
    • A1-35797
    • CS-0319523
    • (2S)-1-Cbz-2-formylpyrrolidine
    • (S)-2-Formyl-pyrrolidine-1-carboxylicacidbenzylester
    • I11669
    • 2alpha-Formylpyrrolidine-1-carboxylic acid benzyl ester
    • MDL： MFCD17214732
    • Inchi： 1S/C13H15NO3/c15-9-12-7-4-8-14(12)13(16)17-10-11-5-2-1-3-6-11/h1-3,5-6,9,12H,4,7-8,10H2/t12-/m0/s1
    • InChI Key： ASNHSGGMNWXBEI-LBPRGKRZSA-N
    • SMILES： O(CC1C=CC=CC=1)C(N1CCC[C@H]1C=O)=O

Computed Properties

  • Exact Mass: 233.10500
  • Monoisotopic Mass: 233.10519334g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 5
  • Complexity: 274
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.7
  • Topological Polar Surface Area: 46.6?2

Experimental Properties

  • Density: 1.263
  • PSA: 46.61000
  • LogP: 1.92440

1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)- Customs Data

  • HS CODE：2933990090
  • Customs Data：

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)- Suppliers

Amadis Chemical Company Limited
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(CAS:71461-30-8)1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)-
Order Number:A1231585
Stock Status:in Stock
Quantity:250mg/1g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 19:02
Price ($):237/670

1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)- Related Literature

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Additional information on 1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)-

Comprehensive Overview of 1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)- (CAS No. 71461-30-8)

1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)- is a chiral organic compound with significant applications in pharmaceutical and chemical research. Its CAS number, 71461-30-8, serves as a unique identifier in chemical databases, ensuring precise tracking and regulatory compliance. This compound belongs to the class of pyrrolidine derivatives, which are widely studied for their role in drug development, particularly in the synthesis of bioactive molecules and enantioselective catalysis.

The structural features of 1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)- include a pyrrolidine ring, a formyl group, and a benzyl ester moiety. These functional groups contribute to its reactivity and versatility in organic synthesis. Researchers often explore its potential as a building block for peptide mimetics and chiral auxiliaries, addressing growing demand in asymmetric synthesis and medicinal chemistry. Recent trends highlight its relevance in green chemistry applications, where sustainable synthesis methods are prioritized.

In the context of user search trends, queries like "pyrrolidine derivatives in drug discovery" or "chiral ester applications" reflect widespread interest in this compound's utility. Analytical techniques such as HPLC and NMR spectroscopy are frequently mentioned alongside CAS 71461-30-8, indicating its importance in quality control and structural verification. The compound's (2S)-configuration also aligns with searches for enantiopure compounds, a hot topic in pharmaceutical manufacturing.

From an industrial perspective, 1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)- is often discussed in patent literature for its role in protease inhibitor development. Its benzyl-protected carboxylate group enables selective deprotection strategies, a feature valued in multistep syntheses. Environmental considerations have spurred research into its biodegradability, with keywords like "eco-friendly chiral synthons" gaining traction in academic publications.

The compound's stability under various pH conditions makes it suitable for catalysis research, particularly in organocatalysis applications. Database analytics reveal that searches for "CAS 71461-30-8 solubility" and "storage conditions for pyrrolidine esters" are common, underscoring practical handling concerns. Recent publications have explored its crystalline forms, addressing the polymorphism interests of formulation scientists.

Emerging applications in bioconjugation chemistry position 1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)- as a candidate for antibody-drug conjugate (ADC) linker development. This aligns with the surge in ADC-related searches, reflecting oncology research priorities. Regulatory databases show no restrictions on this compound, facilitating its global availability for research purposes.

In summary, 1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)- (CAS 71461-30-8) represents a multifaceted tool for synthetic chemists, combining chiral specificity with functional group diversity. Its alignment with trending topics like enantioselective synthesis and green pharmaceuticals ensures continued relevance in both academic and industrial settings.

71461-30-8 (1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)-) Related Products

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Amadis Chemical Company Limited
(CAS:71461-30-8)1-Pyrrolidinecarboxylic acid, 2-formyl-, phenylmethyl ester, (2S)-
A1231585
Purity:99%/99%
Quantity:250mg/1g
Price ($):237/670
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